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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of interferon-alpha production
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Accession:GO:0032647 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of interferon-alpha production.
Synonyms:narrow_synonym: regulation of interferon-alpha biosynthetic process;   regulation of interferon-alpha secretion
 alt_id: GO:0045354;   GO:1902739


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negative regulation of interferon-alpha production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 ISO (PMID:26492563) RGD PMID:26492563 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 ISO (MGI:5568884|PMID:24560620) RGD PMID:24560620 MGI:5568884 NCBI chr10:11,809,531...11,844,184
Ensembl chr10:11,810,926...11,842,482
JBrowse link
G Nmi N-myc (and STAT) interactor ISO (MGI:5546557|PMID:23956435) RGD PMID:23956435 MGI:5546557 NCBI chr 3:37,458,891...37,480,984
Ensembl chr 3:37,458,890...37,480,984
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S IEA
ISO
GO_REF:0000107
(PMID:26231120)
Ensembl
RGD
PMID:26231120 GO_REF:0000107 NCBI chr 9:10,585,360...10,646,205
Ensembl chr 9:10,603,813...10,645,939
JBrowse link
positive regulation of interferon-alpha production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07014739.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr14:29,232,295...29,232,537 JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO (PMID:24784232)
(MGI:5583923|PMID:24784232)
RGD PMID:24784232 MGI:5583923 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Ddx58 DEXD/H-box helicase 58 ISO (PMID:19576794), (PMID:19609254), (PMID:21957149) RGD PMID:19576794, PMID:19609254, PMID:21957149 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Dhx36 DEAH-box helicase 36 ISO (PMID:20696886) RGD PMID:20696886 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:21957149) RGD PMID:21957149 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ISO MGI:3628823 (MGI:4452060|PMID:20457904) RGD PMID:20457904 MGI:4452060 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570
JBrowse link
G Hmgb1 high mobility group box 1 ISO (MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:4367121 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO
IBA
(PMID:17164250)
(MGI:3708392|PMID:17164250)
PMID:21873635
RGD PMID:17164250, PMID:21873635 MGI:3708392, RGD:13792537 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 ISO (PMID:19656871), (PMID:21957149) RGD PMID:19656871, PMID:21957149 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:4365354|PMID:18562536) RGD PMID:18562536 MGI:4365354 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Irf7 interferon regulatory factor 7 ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISS
ISO
GO_REF:0000024
(PMID:16127453), (PMID:19609254), (PMID:21957149)
UniProt
RGD
PMID:16127453, PMID:19609254, PMID:21957149 GO_REF:0000024 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Mmp12 matrix metallopeptidase 12 IEA
ISO
GO_REF:0000107
(MGI:5583923|PMID:24784232)
Ensembl
RGD
PMID:24784232 GO_REF:0000107, MGI:5583923 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO (MGI:5562517|PMID:23871208) RGD PMID:23871208 MGI:5562517 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Tlr3 toll-like receptor 3 ISO (PMID:16286015) RGD PMID:16286015 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISO
GO_REF:0000107
(MGI:4456948|PMID:15356140)
Ensembl
RGD
PMID:15356140 GO_REF:0000107, MGI:4456948 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr7 toll-like receptor 7 ISO (PMID:16286015)
(MGI:3042320|PMID:14976261)
RGD PMID:14976261, PMID:16286015 MGI:3042320 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957
JBrowse link
G Tlr8 toll-like receptor 8 ISO (PMID:16286015) RGD PMID:16286015 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803
JBrowse link
G Tlr9 toll-like receptor 9 ISO (PMID:16286015) RGD PMID:16286015 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:66,012,111...66,062,160
Ensembl chr 4:66,011,915...66,062,089
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    multicellular organismal process 9047
      cytokine production 764
        type I interferon production 85
          regulation of type I interferon production 85
            regulation of interferon-alpha production 28
              negative regulation of interferon-alpha production 4
              positive regulation of interferon-alpha production 24
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        macromolecule metabolic process 10077
          gene expression 6300
            cytokine production 764
              regulation of cytokine production 753
                regulation of type I interferon production 85
                  regulation of interferon-alpha production 28
                    negative regulation of interferon-alpha production 4
                    positive regulation of interferon-alpha production 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.