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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of interferon-beta production
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Accession:GO:0032648 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of interferon-beta production.
Synonyms:exact_synonym: regulation of IFN-beta production
 narrow_synonym: regulation of interferon-beta biosynthetic process;   regulation of interferon-beta secretion
 alt_id: GO:0035547;   GO:0045357


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regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF216 ring finger protein 216 IDA (PMID:19893624) UniProtKB PMID:19893624 NCBI chr 7:5,620,047...5,781,721
Ensembl chr 7:5,620,047...5,781,696
Ensembl chr 7:5,620,047...5,781,696
JBrowse link
G TIRAP TIR domain containing adaptor protein ISS BHF-UCL GO_REF:0000024 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,283,065...126,298,845
JBrowse link
G TRAF3 TNF receptor associated factor 3 ISS UniProtKB GO_REF:0000024 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500
JBrowse link
G TRIM38 tripartite motif containing 38 IEA Ensembl GO_REF:0000107 NCBI chr 6:25,962,723...25,991,231
Ensembl chr 6:25,962,802...25,991,231
JBrowse link
negative regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG9A autophagy related 9A ISO (MGI:5569198|PMID:24670807) MGI PMID:24670807 MGI:5569198 NCBI chr 2:219,219,380...219,229,636
Ensembl chr 2:219,219,380...219,229,717
JBrowse link
G CACTIN cactin, spliceosome C complex subunit IMP (PMID:20829348) UniProtKB PMID:20829348 NCBI chr19:3,610,645...3,626,810
Ensembl chr19:3,610,645...3,626,815
JBrowse link
G CREBBP CREB binding protein ISO (MGI:2151262|PMID:11583620) CAFA PMID:11583620 MGI:2151262 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G IRF3 interferon regulatory factor 3 ISO (MGI:3828224|PMID:18851954) MGI PMID:18851954 MGI:3828224 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 IDA (PMID:21213105) UniProt PMID:21213105 NCBI chr19:54,616,939...54,637,925
Ensembl chr19:54,617,158...54,637,528
JBrowse link
G NLRC3 NLR family CARD domain containing 3 ISS UniProtKB GO_REF:0000024 NCBI chr16:3,539,033...3,577,782
Ensembl chr16:3,539,033...3,577,403
JBrowse link
G NLRX1 NLR family member X1 IEA Ensembl GO_REF:0000107 NCBI chr11:119,168,334...119,184,016
Ensembl chr11:119,166,568...119,184,016
JBrowse link
G NMI N-myc and STAT interactor IEA Ensembl GO_REF:0000107 NCBI chr 2:151,270,465...151,289,668
Ensembl chr 2:151,270,470...151,289,894
JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B IMP (PMID:22750291) UniProtKB PMID:22750291 NCBI chr 2:44,168,853...44,247,330
Ensembl chr 2:44,167,969...44,244,384
JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S IMP (PMID:26231120) UniProtKB PMID:26231120 NCBI chr19:5,205,503...5,340,812
Ensembl chr19:5,158,495...5,340,803
JBrowse link
G PYCARD PYD and CARD domain containing IMP (PMID:19158675) UniProtKB PMID:19158675 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
JBrowse link
G REL REL proto-oncogene, NF-kB subunit IDA (PMID:22065573) CACAO PMID:22065573 NCBI chr 2:60,881,521...60,931,612
Ensembl chr 2:60,881,521...60,931,610
Ensembl chr 2:60,881,521...60,931,610
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit IMP (PMID:22065573) CACAO PMID:22065573 NCBI chr19:45,001,449...45,038,194
Ensembl chr19:45,001,449...45,038,198
JBrowse link
G SIRPA signal regulatory protein alpha ISS ARUK-UCL GO_REF:0000024 NCBI chr20:1,894,167...1,940,592
Ensembl chr20:1,894,167...1,940,592
JBrowse link
G TRAF3IP1 TRAF3 interacting protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:238,320,489...238,400,900
Ensembl chr 2:238,320,441...238,400,897
JBrowse link
G TRAIP TRAF interacting protein IEA Ensembl GO_REF:0000107 NCBI chr 3:49,828,595...49,856,584
Ensembl chr 3:49,828,601...49,856,574
JBrowse link
G YY1 YY1 transcription factor IDA (PMID:16260628) UniProtKB PMID:16260628 NCBI chr14:100,239,144...100,282,788
Ensembl chr14:100,238,298...100,282,788
JBrowse link
positive regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked TAS
IDA
(PMID:18583960), (PMID:18636090)
(PMID:27980081), (PMID:31575075)
UniProtKB
UniProt
PMID:18583960, PMID:18636090, PMID:27980081, PMID:31575075 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472
Ensembl chr  X:41,333,348...41,364,472
JBrowse link
G DDX58 DExD/H-box helicase 58 IDA
IBA
IMP
(PMID:17079289)
(PMID:21873635)
(PMID:19211564), (PMID:19609254), (PMID:19631370), (PMID:21957149)
BHF-UCL
GO_Central
UniProt
PMID:17079289, PMID:19211564, PMID:19609254, PMID:19631370, PMID:21873635, PMID:21957149 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
JBrowse link
G DHX58 DExH-box helicase 58 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:42,101,404...42,112,721
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G DHX9 DExH-box helicase 9 IMP (PMID:21957149) UniProt PMID:21957149 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982
JBrowse link
G FLOT1 flotillin 1 IMP (PMID:25204797) UniProtKB PMID:25204797 NCBI chr 6:30,727,709...30,742,847
Ensembl chr 6:30,727,709...30,742,732
JBrowse link
G HMGB1 high mobility group box 1 IEA Ensembl GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGB2 high mobility group box 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 TAS
IBA
IMP
IDA
(PMID:17079289)
(PMID:21873635)
(PMID:19211564), (PMID:19656871), (PMID:21957149)
(PMID:17600090)
BHF-UCL
GO_Central
UniProt
UniProtKB
PMID:17079289, PMID:17600090, PMID:19211564, PMID:19656871, PMID:21873635, PMID:21957149 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 ISO (MGI:5619426|PMID:24598055) CACAO PMID:24598055 MGI:5619426 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,429...33,359,864
JBrowse link
G IRF1 interferon regulatory factor 1 IMP (PMID:21389130) UniProtKB PMID:21389130 NCBI chr 5:132,481,609...132,490,789
Ensembl chr 5:132,481,609...132,490,777
JBrowse link
G IRF3 interferon regulatory factor 3 TAS
ISS
(PMID:16979567) UniProtKB PMID:16979567 GO_REF:0000024 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF5 interferon regulatory factor 5 IC (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
JBrowse link
G IRF7 interferon regulatory factor 7 IMP
TAS
(PMID:22065573)
(PMID:16979567)
CACAO
UniProtKB
PMID:16979567, PMID:22065573 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G MAVS mitochondrial antiviral signaling protein IDA
IMP
(PMID:16127453)
(PMID:19609254), (PMID:19631370), (PMID:21957149)
BHF-UCL
UniProt
PMID:16127453, PMID:19609254, PMID:19631370, PMID:21957149 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G POLR3A RNA polymerase III subunit A IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr10:77,975,149...78,029,515
Ensembl chr10:77,969,251...78,029,515
JBrowse link
G POLR3B RNA polymerase III subunit B IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr12:106,357,712...106,510,198
Ensembl chr12:106,357,748...106,510,198
JBrowse link
G POLR3C RNA polymerase III subunit C IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr 1:145,823,183...145,844,402
Ensembl chr 1:145,824,088...145,844,402
JBrowse link
G POLR3D RNA polymerase III subunit D IDA (PMID:19631370) UniProtKB PMID:19631370 NCBI chr 8:22,245,104...22,254,601
Ensembl chr 8:22,245,133...22,254,601
JBrowse link
G POLR3F RNA polymerase III subunit F IMP (PMID:19631370) UniProtKB PMID:19631370 NCBI chr20:18,467,390...18,484,646
Ensembl chr20:18,467,389...18,484,646
JBrowse link
G POLR3G RNA polymerase III subunit G IMP (PMID:19609254), (PMID:19631370) UniProtKB PMID:19609254, PMID:19631370 NCBI chr 5:90,473,929...90,514,557
Ensembl chr 5:90,471,748...90,514,557
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISS ARUK-UCL GO_REF:0000024 NCBI chr12:112,418,915...112,509,918
Ensembl chr12:112,418,351...112,509,913
Ensembl chr12:112,418,351...112,509,913
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G RIOK3 RIO kinase 3 IMP (PMID:24807708) UniProtKB PMID:24807708 NCBI chr18:23,452,823...23,483,140
Ensembl chr18:23,453,287...23,486,603
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 NAS (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G RNF135 ring finger protein 135 IMP (PMID:19017631) UniProtKB PMID:19017631 NCBI chr17:30,968,642...30,999,911
Ensembl chr17:30,970,984...30,999,911
JBrowse link
G TBK1 TANK binding kinase 1 IDA (PMID:16127453) BHF-UCL PMID:16127453 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 IEA Ensembl GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
JBrowse link
G TLR2 toll like receptor 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 4:153,684,080...153,710,643
Ensembl chr 4:153,684,070...153,706,260
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR3 toll like receptor 3 ISS
IDA
IMP
(PMID:16286015)
(PMID:12054664)
BHF-UCL
UniProt
PMID:12054664, PMID:16286015 GO_REF:0000024 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,069,152...186,088,069
Ensembl chr 4:186,069,152...186,088,069
JBrowse link
G TLR4 toll like receptor 4 ISS BHF-UCL GO_REF:0000024 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR7 toll like receptor 7 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361
JBrowse link
G TLR8 toll like receptor 8 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169
JBrowse link
G TLR9 toll like receptor 9 ISS
IDA
(PMID:16286015) BHF-UCL
UniProt
PMID:16286015 GO_REF:0000024 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,226,163
JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 ISO (MGI:5619432|PMID:23776228) CACAO PMID:23776228 MGI:5619432 NCBI chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,288
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 IDA (PMID:21102435) UniProtKB PMID:21102435 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,109,720
JBrowse link
G ZFP64 ZFP64 zinc finger protein ISO (MGI:5619431|PMID:23857586) CACAO PMID:23857586 MGI:5619431 NCBI chr20:52,084,011...52,191,789
Ensembl chr20:52,051,663...52,204,308
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    multicellular organismal process 8779
      cytokine production 831
        type I interferon production 133
          regulation of type I interferon production 133
            regulation of interferon-beta production 56
              negative regulation of interferon-beta production 17
              positive regulation of interferon-beta production 36
Path 2
Term Annotations click to browse term
  biological_process 18672
    metabolic process 12302
      organic substance metabolic process 11734
        macromolecule metabolic process 10184
          gene expression 6362
            cytokine production 831
              regulation of cytokine production 813
                regulation of type I interferon production 133
                  regulation of interferon-beta production 56
                    negative regulation of interferon-beta production 17
                    positive regulation of interferon-beta production 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.