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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of interferon-beta production
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Accession:GO:0032648 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of interferon-beta production.
Synonyms:exact_synonym: regulation of IFN-beta production
 narrow_synonym: regulation of interferon-beta biosynthetic process;   regulation of interferon-beta secretion
 alt_id: GO:0035547;   GO:0045357


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regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf216 ring finger protein 216 ISO (PMID:19893624) UniProtKB PMID:19893624 NCBI chrNW_004936765:452,755...592,358 JBrowse link
G Tirap TIR domain containing adaptor protein ISO (MGI:4942245|PMID:14630816) BHF-UCL PMID:14630816 MGI:4942245 NCBI chrNW_004936572:5,926,193...5,938,621 JBrowse link
G Traf3 TNF receptor associated factor 3 ISO (MGI:4839450|PMID:16306937) UniProt PMID:16306937 MGI:4839450 NCBI chrNW_004936835:844,747...955,900 JBrowse link
G Trim38 tripartite motif containing 38 ISO (MGI:5441682|PMID:22539786) MGI PMID:22539786 MGI:5441682 NCBI chrNW_004936671:1,841,722...1,853,804 JBrowse link
negative regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg9a autophagy related 9A ISO (MGI:5569198|PMID:24670807) MGI PMID:24670807 MGI:5569198 NCBI chrNW_004936569:1,635,958...1,645,600 JBrowse link
G Cactin cactin, spliceosome C complex subunit ISO (PMID:20829348) UniProtKB PMID:20829348 NCBI chrNW_004936588:2,051,636...2,061,651 JBrowse link
G Crebbp CREB binding protein ISO (MGI:2151262|PMID:11583620) CAFA PMID:11583620 MGI:2151262 NCBI chrNW_004936694:552,447...663,237 JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:3828224|PMID:18851954) MGI PMID:18851954 MGI:3828224 NCBI chrNW_004936664:3,477,750...3,482,489 JBrowse link
G Nlrc3 NLR family CARD domain containing 3 ISO (MGI:5568884|PMID:24560620) UniProt PMID:24560620 MGI:5568884 NCBI chrNW_004936694:757,121...773,924 JBrowse link
G Nlrx1 NLR family member X1 ISO (MGI:5050761|PMID:21703540) MGI PMID:21703540 MGI:5050761 NCBI chrNW_004936542:4,105,980...4,121,176 JBrowse link
G Nmi N-myc and STAT interactor ISO (MGI:5546557|PMID:23956435) MGI PMID:23956435 MGI:5546557 NCBI chrNW_004936469:26,194,237...26,215,244 JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent 1B ISO (PMID:22750291) UniProtKB PMID:22750291 NCBI chrNW_004936508:7,732,724...7,804,964 JBrowse link
G Ptprs protein tyrosine phosphatase receptor type S ISO (PMID:26231120) UniProtKB PMID:26231120 NCBI chrNW_004936588:3,021,418...3,073,080 JBrowse link
G Pycard PYD and CARD domain containing ISO (PMID:19158675) UniProtKB PMID:19158675 NCBI chrNW_004936501:13,550,702...13,552,774 JBrowse link
G Rel REL proto-oncogene, NF-kB subunit ISO (PMID:22065573) CACAO PMID:22065573 NCBI chrNW_004936491:6,405,493...6,435,096 JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit ISO (PMID:22065573) CACAO PMID:22065573 NCBI chrNW_004936706:1,569,603...1,596,831 JBrowse link
G Sirpa signal regulatory protein alpha ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chrNW_004936485:16,608,317...16,654,552 JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 ISO (MGI:5306204|PMID:22079989) MGI PMID:22079989 MGI:5306204 NCBI chrNW_004936525:115,614...174,641 JBrowse link
G Traip TRAF interacting protein ISO (MGI:5619447|PMID:22945920) CACAO PMID:22945920 MGI:5619447 NCBI chrNW_004936529:1,434,629...1,466,382 JBrowse link
G Yy1 YY1 transcription factor ISO (PMID:16260628) UniProtKB PMID:16260628 NCBI chrNW_004936604:3,911,407...3,945,405 JBrowse link
positive regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3 X-linked ISO (PMID:27980081), (PMID:31575075) UniProt PMID:27980081, PMID:31575075 NCBI chrNW_004936502:7,770,896...7,820,555 JBrowse link
G Ddx58 DExD/H-box helicase 58 ISO (PMID:17079289)
(MGI:5318026|PMID:17942531)
(PMID:19211564), (PMID:19609254), (PMID:19631370), (PMID:21957149)
BHF-UCL
UniProt
PMID:17079289, PMID:17942531, PMID:19211564, PMID:19609254, PMID:19631370, PMID:21957149 MGI:5318026 NCBI chrNW_004936524:1,141,840...1,200,638 JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:21957149) UniProt PMID:21957149 NCBI chrNW_004936481:6,896,487...6,934,938 JBrowse link
G Flot1 flotillin 1 ISO (PMID:25204797) UniProtKB PMID:25204797 NCBI chrNW_004936837:387,012...401,076 JBrowse link
G Hmgb1 high mobility group box 1 ISO (MGI:4367121|PMID:19890330) UniProt PMID:19890330 MGI:4367121 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Hmgb2 high mobility group box 2 ISO (MGI:4367121|PMID:19890330) UniProt PMID:19890330 MGI:4367121 NCBI chrNW_004936516:4,536,664...4,539,331 JBrowse link
G Ifih1 interferon induced with helicase C domain 1 ISO (PMID:17600090)
(PMID:19211564), (PMID:19656871), (PMID:21957149)
UniProtKB
UniProt
PMID:17600090, PMID:19211564, PMID:19656871, PMID:21957149 NCBI chrNW_004936469:16,721,306...16,778,249 JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 ISO (MGI:5619426|PMID:24598055) CACAO PMID:24598055 MGI:5619426 NCBI chrNW_004936500:8,953,809...8,975,261 JBrowse link
G Irf1 interferon regulatory factor 1 ISO (PMID:21389130) UniProtKB PMID:21389130 NCBI chrNW_004936647:2,686,247...2,693,633 JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:4365354|PMID:18562536) UniProt PMID:18562536 MGI:4365354 NCBI chrNW_004936664:3,477,750...3,482,489 JBrowse link
G Irf7 interferon regulatory factor 7 ISO (PMID:22065573) CACAO PMID:22065573 NCBI chrNW_004936888:445,340...448,801 JBrowse link
G Mavs mitochondrial antiviral signaling protein ISO (PMID:16127453)
(PMID:19609254), (PMID:19631370), (PMID:21957149)
BHF-UCL
UniProt
PMID:16127453, PMID:19609254, PMID:19631370, PMID:21957149 NCBI chrNW_004936485:14,842,778...14,859,163 JBrowse link
G Polr3a RNA polymerase III subunit A ISO (PMID:19609254) UniProtKB PMID:19609254 NCBI chrNW_004936521:1,570,863...1,613,410 JBrowse link
G Polr3b RNA polymerase III subunit B ISO (PMID:19609254) UniProtKB PMID:19609254 NCBI chrNW_004936492:8,415,997...8,544,149 JBrowse link
G Polr3c RNA polymerase III subunit C ISO (PMID:19609254) UniProtKB PMID:19609254 NCBI chrNW_004936867:586,798...599,069 JBrowse link
G Polr3d RNA polymerase III subunit D ISO (PMID:19631370) UniProtKB PMID:19631370 NCBI chrNW_004936555:6,051,528...6,057,165 JBrowse link
G Polr3f RNA polymerase III subunit F ISO (PMID:19631370) UniProtKB PMID:19631370 NCBI chrNW_004936485:1,796,857...1,814,186 JBrowse link
G Polr3g RNA polymerase III subunit G ISO (PMID:19609254), (PMID:19631370) UniProtKB PMID:19609254, PMID:19631370 NCBI chrNW_004936469:8,574,120...8,611,643 JBrowse link
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chrNW_004936668:2,602,261...2,687,903 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO (MGI:5562517|PMID:23871208) UniProt PMID:23871208 MGI:5562517 NCBI chrNW_004936690:2,180,804...2,232,869 JBrowse link
G Riok3 RIO kinase 3 ISO (PMID:24807708) UniProtKB PMID:24807708 NCBI chrNW_004936550:2,921,272...2,949,288 JBrowse link
G Rnf135 ring finger protein 135 ISO (PMID:19017631) UniProtKB PMID:19017631 NCBI chrNW_004936538:2,741,308...2,757,042 JBrowse link
G Tbk1 TANK binding kinase 1 ISO (PMID:16127453)
(MGI:3530402|PMID:15661922)
BHF-UCL
MGI
PMID:15661922, PMID:16127453 MGI:3530402 NCBI chrNW_004936545:2,763,755...2,809,229 JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 ISO (MGI:2670551|PMID:12872135)
(MGI:2669022|PMID:12855817)
MGI PMID:12855817, PMID:12872135 MGI:2669022, MGI:2670551 NCBI chrNW_004936588:2,818,909...2,827,797 JBrowse link
G Tlr2 toll like receptor 2 ISO (MGI:4456948|PMID:15356140) BHF-UCL PMID:15356140 MGI:4456948 NCBI chrNW_004936576:522,234...531,660 JBrowse link
G Tlr3 toll like receptor 3 ISO (PMID:16286015)
(MGI:4456948|PMID:15356140)
(PMID:12054664)
UniProt
BHF-UCL
PMID:12054664, PMID:15356140, PMID:16286015 MGI:4456948 NCBI chrNW_004936554:3,370,766...3,388,125 JBrowse link
G Tlr4 toll like receptor 4 ISO (MGI:4456948|PMID:15356140)
(MGI:3530402|PMID:15661922)
BHF-UCL
MGI
PMID:15356140, PMID:15661922 MGI:3530402, MGI:4456948 NCBI chrNW_004936487:6,519,140...6,532,018 JBrowse link
G Tlr7 toll like receptor 7 ISO (PMID:16286015) UniProt PMID:16286015 NCBI chrNW_004936470:2,593,544...2,610,972 JBrowse link
G Tlr8 toll like receptor 8 ISO (PMID:16286015) UniProt PMID:16286015 NCBI chrNW_004936470:2,638,020...2,642,201 JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 ISO (MGI:5619432|PMID:23776228) CACAO PMID:23776228 MGI:5619432 NCBI chrNW_004936536:1,776,065...2,546,286 JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 ISO (PMID:21102435) UniProtKB PMID:21102435 NCBI chrNW_004936592:3,321,564...3,379,015 JBrowse link
G Zfp64 ZFP64 zinc finger protein ISO (MGI:5619431|PMID:23857586) CACAO PMID:23857586 MGI:5619431 NCBI chrNW_004936514:3,028,526...3,100,294 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    multicellular organismal process 6221
      cytokine production 644
        type I interferon production 83
          regulation of type I interferon production 83
            regulation of interferon-beta production 51
              negative regulation of interferon-beta production 16
              positive regulation of interferon-beta production 32
Path 2
Term Annotations click to browse term
  biological_process 12002
    metabolic process 7668
      organic substance metabolic process 7372
        macromolecule metabolic process 6388
          gene expression 3952
            cytokine production 644
              regulation of cytokine production 637
                regulation of type I interferon production 83
                  regulation of interferon-beta production 51
                    negative regulation of interferon-beta production 16
                    positive regulation of interferon-beta production 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.