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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of interleukin-1 production
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Accession:GO:0032692 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.
Synonyms:exact_synonym: down regulation of interleukin-1 production;   downregulation of interleukin-1 production;   negative regulation of IL-1 production
 narrow_synonym: inhibition of interleukin-1 production


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negative regulation of interleukin-1 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:9590127
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1600115
RGD:1624291
negative regulation of interleukin-1 alpha production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:13673772
negative regulation of interleukin-1 alpha secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:1624291
RGD:1600115
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10043380
negative regulation of interleukin-1 beta production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp5 acid phosphatase 5, tartrate resistant JBrowse link 8 23,142,733 23,149,067 RGD:1624291
RGD:1600115
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:8695996
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
RGD:1600115
G Cd33 CD33 molecule JBrowse link 1 98,388,811 98,403,539 RGD:1624291
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:1624291
RGD:1600115
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:9491804
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685562
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12905041
RGD:1600115
RGD:1624291
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1624291
RGD:1600115
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1600115
RGD:1624291
G Mefv MEFV innate immuity regulator, pyrin JBrowse link 10 12,045,813 12,056,229 RGD:1624291
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 10 11,809,531 11,844,184 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
negative regulation of interleukin-1 beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
RGD:1600115
G Cptp ceramide-1-phosphate transfer protein JBrowse link 5 173,314,219 173,318,384 RGD:1600115
RGD:1624291
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
RGD:1600115
G Serpinb1a serpin family B member 1A JBrowse link 17 32,903,089 32,911,498 RGD:1600115
RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1600115
RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
negative regulation of interleukin-1 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
RGD:1600115
G Nlrp12 NLR family, pyrin domain containing 12 JBrowse link 1 64,506,750 64,543,908 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    negative regulation of biological process 5498
      negative regulation of multicellular organismal process 1354
        negative regulation of cytokine production 270
          negative regulation of interleukin-1 production 30
            negative regulation of interleukin-1 alpha production + 3
            negative regulation of interleukin-1 beta production + 22
            negative regulation of interleukin-1 biosynthetic process + 0
            negative regulation of interleukin-1 secretion + 12
Path 2
Term Annotations click to browse term
  biological_process 19245
    biological regulation 13198
      regulation of biological process 12516
        negative regulation of biological process 5498
          negative regulation of multicellular organismal process 1354
            negative regulation of cytokine production 270
              negative regulation of interleukin-1 production 30
                negative regulation of interleukin-1 alpha production + 3
                negative regulation of interleukin-1 beta production + 22
                negative regulation of interleukin-1 biosynthetic process + 0
                negative regulation of interleukin-1 secretion + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.