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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of interferon-alpha production
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Accession:GO:0032727 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.
Synonyms:exact_synonym: up regulation of interferon-alpha production;   upregulation of interferon-alpha production
 narrow_synonym: activation of interferon-alpha production;   positive regulation of interferon-alpha biosynthetic process;   positive regulation of interferon-alpha secretion;   stimulation of interferon-alpha production
 alt_id: GO:0045356;   GO:1902741


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positive regulation of interferon-alpha production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07014739.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr14:29,232,295...29,232,537 JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO
IEA
(MGI:MGI:5583923|PMID:24784232)
GO_REF:0000107
(PMID:24784232)
RGD
Ensembl
PMID:24784232 GO_REF:0000107, MGI:MGI:5583923 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Ddx58 DEXD/H-box helicase 58 ISO (PMID:19576794), (PMID:19609254), (PMID:21957149) RGD PMID:19576794, PMID:19609254, PMID:21957149 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Dhx36 DEAH-box helicase 36 ISO
IEA
(PMID:20696886)
GO_REF:0000107
RGD
Ensembl
PMID:20696886 GO_REF:0000107 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Dhx9 DExH-box helicase 9 ISO
IEA
(PMID:21957149)
GO_REF:0000107
RGD
Ensembl
PMID:21957149 GO_REF:0000107 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 ISO MGI:MGI:3628823 (MGI:MGI:4452060|PMID:20457904) RGD PMID:20457904 MGI:MGI:4452060 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570
JBrowse link
G Hmgb1 high mobility group box 1 ISO (MGI:MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:MGI:4367121 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO
IBA
(PMID:17164250)
PMID:21873635
(MGI:MGI:3708392|PMID:17164250)
RGD PMID:17164250, PMID:21873635 MGI:MGI:3708392, RGD:13792537 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 ISO (PMID:19656871), (PMID:21957149) RGD PMID:19656871, PMID:21957149 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Irf3 interferon regulatory factor 3 ISO (MGI:MGI:4365354|PMID:18562536) RGD PMID:18562536 MGI:MGI:4365354 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Irf7 interferon regulatory factor 7 ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Mavs mitochondrial antiviral signaling protein ISS
ISO
GO_REF:0000024
(PMID:16127453), (PMID:19609254), (PMID:21957149)
UniProt
RGD
PMID:16127453, PMID:19609254, PMID:21957149 GO_REF:0000024 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO
IEA
(MGI:MGI:5583923|PMID:24784232)
GO_REF:0000107
RGD
Ensembl
PMID:24784232 GO_REF:0000107, MGI:MGI:5583923 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO
IEA
(MGI:MGI:5562517|PMID:23871208)
GO_REF:0000107
RGD
Ensembl
PMID:23871208 GO_REF:0000107, MGI:MGI:5562517 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO (PMID:28753426) RGD PMID:28753426 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tbk1 TANK-binding kinase 1 ISO (PMID:16127453) RGD PMID:16127453 NCBI chr 7:63,655,247...63,687,978
Ensembl chr 7:63,655,247...63,687,978
JBrowse link
G Tlr3 toll-like receptor 3 ISO
IEA
(PMID:16286015)
GO_REF:0000107
RGD
Ensembl
PMID:16286015 GO_REF:0000107 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 ISO
IEA
(MGI:MGI:4456948|PMID:15356140)
GO_REF:0000107
RGD
Ensembl
PMID:15356140 GO_REF:0000107, MGI:MGI:4456948 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr7 toll-like receptor 7 ISO
IEA
(MGI:MGI:3042320|PMID:14976261)
GO_REF:0000107
(PMID:16286015)
RGD
Ensembl
PMID:14976261, PMID:16286015 GO_REF:0000107, MGI:MGI:3042320 NCBI chr  X:28,486,836...28,513,004
Ensembl chr  X:28,486,869...28,512,957
JBrowse link
G Tlr8 toll-like receptor 8 ISO
IEA
(PMID:16286015)
GO_REF:0000107
RGD
Ensembl
PMID:16286015 GO_REF:0000107 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803
JBrowse link
G Tlr9 toll-like receptor 9 ISO (PMID:16286015) RGD PMID:16286015 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:66,012,111...66,062,160
Ensembl chr 4:66,011,915...66,062,089
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    multicellular organismal process 9055
      cytokine production 846
        type I interferon production 91
          positive regulation of type I interferon production 54
            positive regulation of interferon-alpha production 24
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      organic substance metabolic process 11636
        macromolecule metabolic process 10081
          gene expression 6295
            cytokine production 846
              regulation of cytokine production 762
                positive regulation of cytokine production 503
                  positive regulation of type I interferon production 54
                    positive regulation of interferon-alpha production 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.