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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of interferon-beta production
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Accession:GO:0032728 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
Synonyms:exact_synonym: positive regulation of IFN-beta production;   up regulation of interferon-beta production;   upregulation of interferon-beta production
 narrow_synonym: activation of interferon-beta production;   positive regulation of interferon-beta biosynthetic process;   positive regulation of interferon-beta secretion;   stimulation of interferon-beta production
 alt_id: GO:0035549;   GO:0045359


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positive regulation of interferon-beta production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked TAS
IDA
(PMID:18583960), (PMID:18636090)
(PMID:27980081), (PMID:31575075)
UniProtKB
UniProt
PMID:18583960, PMID:18636090, PMID:27980081, PMID:31575075 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472
Ensembl chr  X:41,333,348...41,364,472
JBrowse link
G DDX58 DExD/H-box helicase 58 IDA
IMP
IBA
(PMID:17079289)
(PMID:19211564), (PMID:19609254), (PMID:19631370), (PMID:21957149)
(PMID:21873635)
BHF-UCL
UniProt
GO_Central
PMID:17079289, PMID:19211564, PMID:19609254, PMID:19631370, PMID:21873635, PMID:21957149 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
JBrowse link
G DHX58 DExH-box helicase 58 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:42,101,404...42,112,721
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G DHX9 DExH-box helicase 9 IMP (PMID:21957149) UniProt PMID:21957149 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982
JBrowse link
G FLOT1 flotillin 1 IMP (PMID:25204797) UniProtKB PMID:25204797 NCBI chr 6:30,727,709...30,742,847
Ensembl chr 6:30,727,709...30,742,732
JBrowse link
G HMGB1 high mobility group box 1 IEA Ensembl GO_REF:0000107 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGB2 high mobility group box 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 TAS
IMP
IBA
IDA
(PMID:17079289)
(PMID:19211564), (PMID:19656871), (PMID:21957149)
(PMID:21873635)
(PMID:17600090)
BHF-UCL
UniProt
GO_Central
UniProtKB
PMID:17079289, PMID:17600090, PMID:19211564, PMID:19656871, PMID:21873635, PMID:21957149 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 ISO (MGI:MGI:5619426|PMID:24598055) CACAO PMID:24598055 MGI:MGI:5619426 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,429...33,359,864
JBrowse link
G IRF1 interferon regulatory factor 1 IMP (PMID:21389130) UniProtKB PMID:21389130 NCBI chr 5:132,481,609...132,490,789
Ensembl chr 5:132,481,609...132,490,777
JBrowse link
G IRF3 interferon regulatory factor 3 TAS
ISS
(PMID:16979567) UniProtKB PMID:16979567 GO_REF:0000024 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF5 interferon regulatory factor 5 IC (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
JBrowse link
G IRF7 interferon regulatory factor 7 IMP
TAS
(PMID:22065573)
(PMID:16979567)
CACAO
UniProtKB
PMID:16979567, PMID:22065573 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G MAVS mitochondrial antiviral signaling protein IDA
IMP
(PMID:16127453)
(PMID:19609254), (PMID:19631370), (PMID:21957149)
BHF-UCL
UniProt
PMID:16127453, PMID:19609254, PMID:19631370, PMID:21957149 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G POLR3A RNA polymerase III subunit A IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr10:77,975,149...78,029,515
Ensembl chr10:77,969,251...78,029,515
JBrowse link
G POLR3B RNA polymerase III subunit B IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr12:106,357,712...106,510,198
Ensembl chr12:106,357,748...106,510,198
JBrowse link
G POLR3C RNA polymerase III subunit C IMP (PMID:19609254) UniProtKB PMID:19609254 NCBI chr 1:145,823,183...145,844,402
Ensembl chr 1:145,824,088...145,844,402
JBrowse link
G POLR3D RNA polymerase III subunit D IDA (PMID:19631370) UniProtKB PMID:19631370 NCBI chr 8:22,245,104...22,254,601
Ensembl chr 8:22,245,133...22,254,601
JBrowse link
G POLR3F RNA polymerase III subunit F IMP (PMID:19631370) UniProtKB PMID:19631370 NCBI chr20:18,467,390...18,484,646
Ensembl chr20:18,467,389...18,484,646
JBrowse link
G POLR3G RNA polymerase III subunit G IMP (PMID:19609254), (PMID:19631370) UniProtKB PMID:19609254, PMID:19631370 NCBI chr 5:90,473,929...90,514,557
Ensembl chr 5:90,471,748...90,514,557
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISS ARUK-UCL GO_REF:0000024 NCBI chr12:112,418,915...112,509,918
Ensembl chr12:112,418,351...112,509,913
Ensembl chr12:112,418,351...112,509,913
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G RIOK3 RIO kinase 3 IMP (PMID:24807708) UniProtKB PMID:24807708 NCBI chr18:23,452,823...23,483,140
Ensembl chr18:23,453,287...23,486,603
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 NAS (PMID:22412986) BHF-UCL PMID:22412986 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G RNF135 ring finger protein 135 IMP (PMID:19017631) UniProtKB PMID:19017631 NCBI chr17:30,968,642...30,999,911
Ensembl chr17:30,970,984...30,999,911
JBrowse link
G TBK1 TANK binding kinase 1 IDA (PMID:16127453) BHF-UCL PMID:16127453 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TICAM1 toll like receptor adaptor molecule 1 IEA Ensembl GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
JBrowse link
G TLR2 toll like receptor 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 4:153,684,080...153,710,643
Ensembl chr 4:153,684,070...153,706,260
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR3 toll like receptor 3 ISS
IDA
IMP
(PMID:16286015)
(PMID:12054664)
BHF-UCL
UniProt
PMID:12054664, PMID:16286015 GO_REF:0000024 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,069,152...186,088,069
Ensembl chr 4:186,069,152...186,088,069
JBrowse link
G TLR4 toll like receptor 4 ISS BHF-UCL GO_REF:0000024 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR7 toll like receptor 7 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361
JBrowse link
G TLR8 toll like receptor 8 IDA (PMID:16286015) UniProt PMID:16286015 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169
JBrowse link
G TLR9 toll like receptor 9 ISS
IDA
(PMID:16286015) BHF-UCL
UniProt
PMID:16286015 GO_REF:0000024 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,226,163
JBrowse link
G ZBTB20 zinc finger and BTB domain containing 20 ISO (MGI:MGI:5619432|PMID:23776228) CACAO PMID:23776228 MGI:MGI:5619432 NCBI chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,288
Ensembl chr 3:114,314,500...115,147,288
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 IDA (PMID:21102435) UniProtKB PMID:21102435 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,109,720
JBrowse link
G ZFP64 ZFP64 zinc finger protein ISO (MGI:MGI:5619431|PMID:23857586) CACAO PMID:23857586 MGI:MGI:5619431 NCBI chr20:52,084,011...52,191,789
Ensembl chr20:52,051,663...52,204,308
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    multicellular organismal process 8775
      cytokine production 831
        type I interferon production 133
          positive regulation of type I interferon production 81
            positive regulation of interferon-beta production 36
Path 2
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      organic substance metabolic process 11733
        macromolecule metabolic process 10186
          gene expression 6364
            cytokine production 831
              regulation of cytokine production 813
                positive regulation of cytokine production 508
                  positive regulation of type I interferon production 81
                    positive regulation of interferon-beta production 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.