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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of interleukin-6 production
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Accession:GO:0032755 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
Synonyms:exact_synonym: positive regulation of IL-6 production;   up regulation of interleukin-6 production;   upregulation of interleukin-6 production
 narrow_synonym: activation of interleukin-6 production;   stimulation of interleukin-6 production


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positive regulation of interleukin-6 production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07009373.1 RGD:13792537
G AABR07019870.1 RGD:13792537
G AABR07025074.1 RGD:13792537
G AABR07030543.1 RGD:13792537
G AABR07040430.1 RGD:13792537
G AABR07040480.1 RGD:13792537
G AABR07041586.2 RGD:13792537
G AABR07060165.1 RGD:13792537
G AABR07060287.1 RGD:13792537
G AABR07067274.1 RGD:13792537
G AC094217.2 RGD:13792537
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325294
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1624291
RGD:1600115
G Akirin2 akirin 2 JBrowse link 5 50,001,945 50,016,544 RGD:1624291
RGD:1600115
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
RGD:1600115
G Bsg basigin (Ok blood group) JBrowse link 7 12,875,536 12,882,753 RGD:1624291
G C1qtnf4 C1q and TNF related 4 JBrowse link 3 79,713,580 79,718,018 RGD:1624291
G Card9 caspase recruitment domain family, member 9 JBrowse link 3 3,798,346 3,806,841 RGD:1624291
RGD:1600115
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:1598562
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5130956
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:1624291
RGD:1600115
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:1600115
G Hmg1l1 high-mobility group (nonhistone chromosomal) protein 1-like 1 JBrowse link 19 59,984,234 59,985,494 RGD:13792537
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10054071
RGD:1624291
RGD:13792537
RGD:10402175
G Hmgb4 high-mobility group box 4 JBrowse link 5 146,445,545 146,446,227 RGD:13792537
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
G Il17d interleukin 17D JBrowse link 15 37,790,211 37,807,653 RGD:1624291
RGD:1600115
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:2311093
RGD:13792537
RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1358666
RGD:1624291
RGD:13792537
G Il1f10 interleukin 1 family member 10 JBrowse link 3 1,408,560 1,416,601 RGD:13792537
G Il1rl2 interleukin 1 receptor-like 2 JBrowse link 9 47,044,870 47,093,679 RGD:1624291
RGD:1600115
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:13792537
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Il36a interleukin 36, alpha JBrowse link 3 1,330,790 1,335,811 RGD:1624291
RGD:13792537
G Il36b interleukin 36, beta JBrowse link 3 1,366,123 1,464,851 RGD:1624291
RGD:13792537
G Il36g interleukin 36, gamma JBrowse link 3 1,285,658 1,291,836 RGD:1624291
RGD:13792537
G Il36rn interleukin 36 receptor antagonist JBrowse link 3 1,385,256 1,392,275 RGD:13792537
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1624291
G Inava innate immunity activator JBrowse link 13 53,088,438 53,108,713 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:1624291
RGD:1600115
G LOC108349258 high mobility group protein B4-like JBrowse link X 142,344,626 142,345,439 RGD:13792537
G LOC108350839 high mobility group protein B1-like JBrowse link 4 92,431,517 92,432,354 RGD:13792537
G LOC681067 similar to RIKEN cDNA 1700001F22 JBrowse link X 132,424,185 132,424,955 RGD:13792537
G LOC691030 similar to RIKEN cDNA 1700001F22 JBrowse link X 130,794,079 130,794,824 RGD:13792537
G Mapk13 mitogen activated protein kinase 13 JBrowse link 20 6,018,374 6,027,467 RGD:1624291
RGD:1600115
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1600115
RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
RGD:1600115
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:1624291
RGD:1600115
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
RGD:1600115
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:1600115
RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
G Rab7b Rab7b, member RAS oncogene family JBrowse link 13 48,456,143 48,483,714 RGD:1624291
RGD:1600115
G RGD1560585 similar to RIKEN cDNA 1700001F22 JBrowse link X 144,001,166 144,001,891 RGD:13792537
G RGD1561558 similar to RIKEN cDNA 1700001F22 JBrowse link X 158,261,123 158,261,953 RGD:13792537
G RGD1566225 similar to RIKEN cDNA 1700001F22 JBrowse link X 137,197,195 137,197,990 RGD:13792537
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
RGD:1600115
G Scimp SLP adaptor and CSK interacting membrane protein JBrowse link 10 57,415,429 57,436,412 RGD:1600115
RGD:1624291
G Spon2 spondin 2 JBrowse link 14 82,815,158 82,824,529 RGD:1624291
G Tbc1d23 TBC1 domain family, member 23 JBrowse link 11 45,401,396 45,459,841 RGD:1624291
RGD:1600115
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Ticam2 toll-like receptor adaptor molecule 2 JBrowse link 18 40,555,106 40,572,569 RGD:1624291
RGD:1600115
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:13792537
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:13792537
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
RGD:13792537
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
RGD:1600115
G Tnfsf9 TNF superfamily member 9 JBrowse link 9 9,909,942 9,912,276 RGD:2317345
G Tslp thymic stromal lymphopoietin JBrowse link 18 25,613,601 25,618,066 RGD:1624291
G Tut4 terminal uridylyl transferase 4 JBrowse link 5 128,063,880 128,168,726 RGD:1624291
RGD:1600115
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:1642791
G Vegfd vascular endothelial growth factor D JBrowse link X 31,816,480 31,852,239 RGD:2314331
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
G Zbtb20 zinc finger and BTB domain containing 20 JBrowse link 11 62,014,925 62,561,113 RGD:1624291
RGD:1600115
G Zfp64 zinc finger protein 64 JBrowse link 3 165,713,070 165,741,932 RGD:1624291
positive regulation of interleukin-6 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1600115
RGD:1624291
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1600115
RGD:1624291
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
RGD:1600115
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13513988
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
RGD:1600115
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G LOC103694380 tumor necrosis factor-like JBrowse link 20 4,855,792 4,858,447 RGD:13800534
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10043184
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:13800534
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
RGD:1600115
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:13800534
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
RGD:1600115
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
RGD:1600115
positive regulation of interleukin-6 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:11533328
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:1600115
RGD:1624291
G Arid5a AT-rich interaction domain 5A JBrowse link 9 42,871,907 42,886,725 RGD:1624291
G C1qtnf4 C1q and TNF related 4 JBrowse link 3 79,713,580 79,718,018 RGD:1624291
RGD:1600115
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Defb25 defensin beta 25 JBrowse link 3 148,103,643 148,104,483 RGD:1624291
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
RGD:1600115
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1600115
RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:10402845
G Hyal2 hyaluronidase 2 JBrowse link 8 116,324,062 116,328,978 RGD:1600115
RGD:1624291
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 3 48,557,696 48,604,097 RGD:1624291
RGD:1600115
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:1600115
RGD:1624291
G Il17f interleukin 17F JBrowse link 9 26,885,702 26,897,219 RGD:1600115
RGD:1624291
G Il17rc interleukin 17 receptor C JBrowse link 4 145,426,647 145,439,845 RGD:1624291
RGD:1600115
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:15023467
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Il1rap interleukin 1 receptor accessory protein JBrowse link 11 77,456,648 77,593,208 RGD:1600115
RGD:1624291
G Lcn11 lipocalin 11 JBrowse link 3 2,935,396 2,938,883 RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
RGD:13792537
G Lilra5 leukocyte immunoglobulin like receptor A5 JBrowse link 1 73,655,767 73,682,232 RGD:1624291
G LOC103694380 tumor necrosis factor-like JBrowse link 20 4,855,792 4,858,447 RGD:13800534
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:1600115
RGD:1624291
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1624291
RGD:1600115
G Mbp myelin basic protein JBrowse link 18 79,326,738 79,437,310 RGD:1600115
RGD:1624291
G Ncl nucleolin JBrowse link 9 93,369,119 93,377,643 RGD:9686449
G Nlrp10 NLR family, pyrin domain containing 10 JBrowse link 1 173,521,412 173,528,969 RGD:1624291
RGD:1600115
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Selenok selenoprotein K JBrowse link 16 6,035,926 6,044,240 RGD:1600115
RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1600115
RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:13800534
RGD:14985258
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
RGD:1600115
G Unc93b1 unc-93 homolog B1, TLR signaling regulator JBrowse link 1 219,172,987 219,183,941 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    positive regulation of biological process 6441
      positive regulation of multicellular organismal process 2026
        positive regulation of cytokine production 490
          positive regulation of interleukin-6 production 122
            positive regulation of interleukin-6 biosynthetic process 17
            positive regulation of interleukin-6 secretion 38
Path 2
Term Annotations click to browse term
  biological_process 19317
    biological regulation 13340
      regulation of biological process 12656
        positive regulation of biological process 6441
          positive regulation of multicellular organismal process 2026
            positive regulation of cytokine production 490
              positive regulation of interleukin-6 production 122
                positive regulation of interleukin-6 biosynthetic process 17
                positive regulation of interleukin-6 secretion 38
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.