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Term:SMN complex
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Accession:GO:0032797 term browser browse the term
Definition:A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.
Comment:Note that a larger complex containing Sm proteins and other subunits is also sometimes referred to as the 'SMN complex'. The larger complex is represented by 'SMN-Sm protein complex ; GO:0034719'.
Synonyms:exact_synonym: SMN core complex;   survival motor neuron complex

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SMN complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx20 DEAD-box helicase 20 JBrowse link 2 208,144,142 208,154,764 RGD:1624291
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1600115
G Gemin2 gem (nuclear organelle) associated protein 2 JBrowse link 6 80,108,751 80,122,382 RGD:1624291
G Gemin4 gem (nuclear organelle) associated protein 4 JBrowse link 10 64,364,808 64,375,885 RGD:1624291
G Gemin5 gem (nuclear organelle) associated protein 5 JBrowse link 10 43,552,260 43,599,241 RGD:1624291
G Gemin6 gem (nuclear organelle) associated protein 6 JBrowse link 6 2,907,040 2,911,577 RGD:1624291
G Gemin7 gem (nuclear organelle) associated protein 7 JBrowse link 1 80,473,966 80,487,976 RGD:1624291
G Gemin7l1 gem (nuclear organelle) associated protein 7-like 1 JBrowse link 4 78,954,274 78,955,038 RGD:13792537
G Gemin8 gem (nuclear organelle) associated protein 8 JBrowse link X 29,806,605 29,825,439 RGD:1624291
G Smn1 survival of motor neuron 1, telomeric JBrowse link 2 30,360,101 30,371,147 RGD:1600115
G Strap serine/threonine kinase receptor associated protein JBrowse link 4 171,730,629 171,744,877 RGD:1624291

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  cellular_component 19951
    protein-containing complex 5828
      SMN complex 11
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.