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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerulus development
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Accession:GO:0032835 term browser browse the term
Definition:The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.
Synonyms:exact_synonym: glomerular development


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glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2 BCL2 apoptosis regulator JBrowse link 18 56,481,212 56,679,012 RGD:9068941
G C5 complement C5 JBrowse link 9 92,069,574 92,202,513 RGD:9068941
G CFH complement factor H JBrowse link 1 172,155,882 172,251,632 RGD:9068941
G ENPEP glutamyl aminopeptidase JBrowse link 4 102,969,397 103,056,978 RGD:9068941
G HEYL hes related family bHLH transcription factor with YRPW motif like JBrowse link 1 38,913,549 38,929,798 RGD:9068941
G PLCE1 phospholipase C epsilon 1 JBrowse link 10 90,731,695 91,065,846 RGD:9068941
G PTPRO protein tyrosine phosphatase receptor type O JBrowse link 12 15,329,314 15,594,787 RGD:9068941
G TCF21 transcription factor 21 JBrowse link 6 131,656,582 131,662,983 RGD:9068941
G VANGL2 VANGL planar cell polarity protein 2 JBrowse link 1 135,754,897 135,783,031 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 11 32,349,807 32,398,494 RGD:9068941
G WWTR1 WW domain containing transcription regulator 1 JBrowse link 3 146,536,564 146,678,847 RGD:9068941
glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G COL4A3 collagen type IV alpha 3 chain JBrowse link 2B 114,410,703 114,559,336 RGD:9068941
G COL4A4 collagen type IV alpha 4 chain JBrowse link 2B 114,227,135 114,410,564 RGD:9068941
G EXT1 exostosin glycosyltransferase 1 JBrowse link 8 114,489,325 114,803,763 RGD:9068941
G MPV17 mitochondrial inner membrane protein MPV17 JBrowse link 2A 27,311,551 27,325,249 RGD:9068941
G MYO1E myosin IE JBrowse link 15 38,106,599 38,343,040 RGD:9068941
G NID1 nidogen 1 JBrowse link 1 211,543,294 211,631,769 RGD:9068941
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 19 32,742,802 32,770,600 RGD:9068941
G SULF1 sulfatase 1 JBrowse link 8 65,992,961 66,194,112 RGD:9068941
G SULF2 sulfatase 2 JBrowse link 20 43,992,927 44,122,598 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 11 32,349,807 32,398,494 RGD:9068941
glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 14 34,542,132 34,549,286 RGD:9068941
G NOTCH2 notch receptor 2 JBrowse link 1 82,457,829 82,615,142 RGD:9068941
G NOTCH3 notch receptor 3 JBrowse link 19 14,692,571 14,733,758 RGD:9068941
glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD34 CD34 molecule JBrowse link 1 183,459,028 183,489,583 RGD:9068941
G FOXC2 forkhead box C2 JBrowse link 16 67,237,476 67,239,545 RGD:9068941
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 17 58,417,134 58,526,409 RGD:9068941
glomerular epithelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXC1 forkhead box C1 JBrowse link 6 1,429,051 1,433,180 RGD:9068941
glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTA2 actin alpha 2, smooth muscle JBrowse link 10 85,660,983 85,678,729 RGD:9068941
G FOXC2 forkhead box C2 JBrowse link 16 67,237,476 67,239,545 RGD:9068941
G LOC100987218 G-protein coupled receptor 4 JBrowse link 19 42,594,996 42,608,032 RGD:9068941
G NOTCH1 notch receptor 1 JBrowse link 9 107,568,670 107,621,032 RGD:9068941
glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGR1 early growth response 1 JBrowse link 5 133,845,305 133,849,291 RGD:9068941
glomerular parietal epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXJ1 forkhead box J1 JBrowse link 17 70,084,920 70,089,865 RGD:9068941
glomerular parietal epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD24 CD24 molecule JBrowse link 6 104,783,720 104,789,509 RGD:9068941
G PROM1 prominin 1 JBrowse link 4 10,405,299 10,519,518 RGD:9068941
glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AMPD2 adenosine monophosphate deaminase 2 JBrowse link 1 111,997,440 112,009,662 RGD:9068941
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 20 28,647,004 28,727,865 RGD:9068941
G BMP4 bone morphogenetic protein 4 JBrowse link 14 34,542,132 34,549,286 RGD:9068941
G JAG1 jagged canonical Notch ligand 1 JBrowse link 20 10,582,234 10,618,507 RGD:9068941
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 7 69,943,704 71,395,176 RGD:9068941
G MYO1E myosin IE JBrowse link 15 38,106,599 38,343,040 RGD:9068941
G NOTCH2 notch receptor 2 JBrowse link 1 82,457,829 82,615,142 RGD:9068941
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 19 32,742,802 32,770,600 RGD:9068941
G PODXL podocalyxin like JBrowse link 7 123,467,140 123,523,503 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 11 32,349,807 32,398,494 RGD:9068941
glomerular visceral epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BASP1 brain abundant membrane attached signal protein 1 JBrowse link 5 17,521,054 17,580,999 RGD:9068941
G CD24 CD24 molecule JBrowse link 6 104,783,720 104,789,509 RGD:9068941
G EXT1 exostosin glycosyltransferase 1 JBrowse link 8 114,489,325 114,803,763 RGD:9068941
G FOXC2 forkhead box C2 JBrowse link 16 67,237,476 67,239,545 RGD:9068941
G KLF15 Kruppel like factor 15 JBrowse link 3 123,395,678 123,410,514 RGD:9068941
G PROM1 prominin 1 JBrowse link 4 10,405,299 10,519,518 RGD:9068941
G PTPRO protein tyrosine phosphatase receptor type O JBrowse link 12 15,329,314 15,594,787 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 11 32,349,807 32,398,494 RGD:9068941
glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 7 17,949,254 17,998,737 RGD:9068941
G CTNND1 catenin delta 1 JBrowse link 11 53,000,582 53,058,054 RGD:9068941
G KIRREL3 kirre like nephrin family adhesion molecule 3 JBrowse link 11 121,236,962 121,821,806 RGD:9068941
G MEF2C myocyte enhancer factor 2C JBrowse link 5 26,480,489 26,650,813 RGD:9068941
G MTSS1 MTSS I-BAR domain containing 1 JBrowse link 8 121,235,545 121,413,037 RGD:9068941
glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANGPT1 angiopoietin 1 JBrowse link 8 103,893,234 104,137,661 RGD:9068941
G ANGPT2 angiopoietin 2 JBrowse link 8 718,367 782,534 RGD:9068941
G HES1 hes family bHLH transcription factor 1 JBrowse link 3 191,432,513 191,435,387 RGD:9068941
G TEK TEK receptor tyrosine kinase JBrowse link 9 26,955,339 27,077,809 RGD:9068941
metanephric glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LAMB2 laminin subunit beta 2 JBrowse link 3 49,045,419 49,057,340 RGD:9068941
metanephric glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRA platelet derived growth factor receptor alpha JBrowse link 4 69,639,081 69,709,870 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 145,538,330 145,580,312 RGD:9068941
G TCF21 transcription factor 21 JBrowse link 6 131,656,582 131,662,983 RGD:9068941
metanephric glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B JBrowse link 22 20,127,223 20,148,407 RGD:9068941
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B JBrowse link 22 20,127,223 20,148,407 RGD:9068941
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD34 CD34 molecule JBrowse link 1 183,459,028 183,489,583 RGD:9068941
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B JBrowse link 22 20,127,223 20,148,407 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 145,538,330 145,580,312 RGD:9068941
metanephric glomerular mesangium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 145,538,330 145,580,312 RGD:9068941
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LAMB2 laminin subunit beta 2 JBrowse link 3 49,045,419 49,057,340 RGD:9068941
G NPHS2 NPHS2 stomatin family member, podocin JBrowse link 1 155,038,753 155,064,332 RGD:9068941
metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link 11 27,330,279 27,437,201 RGD:9068941
G LHX1 LIM homeobox 1 JBrowse link 17 20,134,308 20,140,652 RGD:9068941
metanephric glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 145,538,330 145,580,312 RGD:9068941
metanephric glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AQP1 aquaporin 1 (Colton blood group) JBrowse link 7 31,524,933 31,538,602 RGD:9068941
G OSR1 odd-skipped related transcription factor 1 JBrowse link 2A 19,333,101 19,340,267 RGD:9068941
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 14 34,542,132 34,549,286 RGD:9068941
G BMP7 bone morphogenetic protein 7 JBrowse link 20 53,509,484 53,606,889 RGD:9068941
G IFNG interferon gamma JBrowse link 12 65,663,764 65,668,732 RGD:9068941
negative regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 14 34,542,132 34,549,286 RGD:9068941
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WT1 WT1 transcription factor JBrowse link 11 32,349,807 32,398,494 RGD:9068941
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3AR1 complement C3a receptor 1 JBrowse link 12 8,178,064 8,186,206 RGD:9068941
G CFLAR CASP8 and FADD like apoptosis regulator JBrowse link 2B 88,373,057 88,429,959 RGD:9068941
G IL6R interleukin 6 receptor JBrowse link 1 129,761,914 129,824,386 RGD:9068941
G ITGB3 integrin subunit beta 3 JBrowse link 17 10,134,450 10,194,596 RGD:9068941
G PDGFB platelet derived growth factor subunit B JBrowse link 22 20,127,223 20,148,407 RGD:9068941
G PDGFD platelet derived growth factor D JBrowse link 11 98,852,652 99,110,147 RGD:9068941
G SERPINB7 serpin family B member 7 JBrowse link 18 57,112,242 57,164,213 RGD:9068941
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGR1 early growth response 1 JBrowse link 5 133,845,305 133,849,291 RGD:9068941
positive regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NOG noggin JBrowse link 17 50,669,186 50,671,081 RGD:9068941
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 183,876,051 183,889,723 RGD:9068941
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTR2 angiotensin II receptor type 2 JBrowse link X 105,252,903 105,257,171 RGD:9068941
G PAX2 paired box 2 JBrowse link 10 97,344,978 97,429,086 RGD:9068941
G RET ret proto-oncogene JBrowse link 10 40,050,396 40,103,629 RGD:9068941
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFA platelet derived growth factor subunit A JBrowse link 7 648,722 672,023 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12490
    developmental process 5767
      anatomical structure development 5384
        glomerulus development 73
          glomerular basement membrane development + 11
          glomerular epithelium development + 25
          glomerulus morphogenesis + 11
          glomerulus vasculature development + 30
          mesonephric glomerulus development + 0
          metanephric glomerulus development + 17
          negative regulation of glomerulus development + 4
          positive regulation of glomerulus development + 13
          pronephric glomerulus development + 0
          regulation of glomerulus development + 18
Path 2
Term Annotations click to browse term
  biological_process 12490
    developmental process 5767
      anatomical structure development 5384
        multicellular organism development 4925
          system development 4653
            urogenital system development 414
              renal system development 368
                kidney development 354
                  nephron development 165
                    glomerulus development 73
                      glomerular basement membrane development + 11
                      glomerular epithelium development + 25
                      glomerulus morphogenesis + 11
                      glomerulus vasculature development + 30
                      mesonephric glomerulus development + 0
                      metanephric glomerulus development + 17
                      negative regulation of glomerulus development + 4
                      positive regulation of glomerulus development + 13
                      pronephric glomerulus development + 0
                      regulation of glomerulus development + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.