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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerulus development
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Accession:GO:0032835 term browser browse the term
Definition:The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.
Synonyms:exact_synonym: glomerular development


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glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2 apoptosis regulator JBrowse link NW_004955402 46,911,125 47,084,214 RGD:9068941
G Enpep glutamyl aminopeptidase JBrowse link NW_004955457 15,863,881 15,943,074 RGD:9068941
G Heyl hes related family bHLH transcription factor with YRPW motif like JBrowse link NW_004955452 17,137,066 17,152,714 RGD:9068941
G Plce1 phospholipase C epsilon 1 JBrowse link NW_004955507 555,570 825,568 RGD:9068941
G Ptpro protein tyrosine phosphatase receptor type O JBrowse link NW_004955413 12,019,026 12,248,026 RGD:9068941
G Tcf21 transcription factor 21 JBrowse link NW_004955439 2,617,562 2,620,613 RGD:9068941
G Vangl2 VANGL planar cell polarity protein 2 JBrowse link NW_004955468 12,162,084 12,189,322 RGD:9068941
G Wt1 WT1 transcription factor JBrowse link NW_004955476 10,464,688 10,504,473 RGD:9068941
G Wwtr1 WW domain containing transcription regulator 1 JBrowse link NW_004955448 745,419 868,313 RGD:9068941
glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col4a3 collagen type IV alpha 3 chain JBrowse link NW_004955453 7,261,278 7,351,414 RGD:9068941
G Col4a4 collagen type IV alpha 4 chain JBrowse link NW_004955453 7,405,167 7,524,038 RGD:9068941
G Ext1 exostosin glycosyltransferase 1 JBrowse link NW_004955417 23,798,044 24,067,759 RGD:9068941
G Mpv17 mitochondrial inner membrane protein MPV17 JBrowse link NW_004955469 9,279,540 9,292,012 RGD:9068941
G Myo1e myosin IE JBrowse link NW_004955450 15,421,843 15,551,680 RGD:9068941
G Nid1 nidogen 1 JBrowse link NW_004955492 4,014,912 4,096,659 RGD:9068941
G Nphs1 NPHS1 adhesion molecule, nephrin JBrowse link NW_004955468 2,715,728 2,734,174 RGD:9068941
G Sulf1 sulfatase 1 JBrowse link NW_004955444 9,902,334 10,066,929 RGD:9068941
G Sulf2 sulfatase 2 JBrowse link NW_004955445 9,919,472 10,020,491 RGD:9068941
G Wt1 WT1 transcription factor JBrowse link NW_004955476 10,464,688 10,504,473 RGD:9068941
glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
G Notch2 notch receptor 2 JBrowse link NW_004955568 1,660,357 1,812,285 RGD:9068941
G Notch3 notch receptor 3 JBrowse link NW_004955495 8,012,370 8,048,616 RGD:9068941
glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 molecule JBrowse link NW_004955406 43,116,688 43,130,405 RGD:9068941
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link NW_004955478 7,448,584 7,531,860 RGD:9068941
glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link NW_004955425 4,023,001 4,039,980 RGD:9068941
G Gpr4 G protein-coupled receptor 4 JBrowse link NW_004955574 85,619 87,928 RGD:9068941
G Notch1 notch receptor 1 JBrowse link NW_004955513 4,225,939 4,264,875 RGD:9068941
glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link NW_004955418 2,001,509 2,005,269 RGD:9068941
glomerular parietal epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link NW_004955506 6,127,551 6,132,302 RGD:9068941
glomerular parietal epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link NW_004955411 32,270,881 32,275,236 RGD:9068941
G Prom1 prominin 1 JBrowse link NW_004955480 7,955,501 8,059,537 RGD:9068941
glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ampd2 adenosine monophosphate deaminase 2 JBrowse link NW_004955435 13,029,377 13,040,972 RGD:9068941
G Asxl1 ASXL transcriptional regulator 1 JBrowse link NW_004955422 28,662,392 28,721,896 RGD:9068941
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
G Jag1 jagged canonical Notch ligand 1 JBrowse link NW_004955415 20,490,414 20,526,068 RGD:9068941
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link NW_004955410 6,739,115 7,295,027 RGD:9068941
G Myo1e myosin IE JBrowse link NW_004955450 15,421,843 15,551,680 RGD:9068941
G Notch2 notch receptor 2 JBrowse link NW_004955568 1,660,357 1,812,285 RGD:9068941
G Nphs1 NPHS1 adhesion molecule, nephrin JBrowse link NW_004955468 2,715,728 2,734,174 RGD:9068941
G Podxl podocalyxin like JBrowse link NW_004955410 36,191,797 36,239,970 RGD:9068941
G Wt1 WT1 transcription factor JBrowse link NW_004955476 10,464,688 10,504,473 RGD:9068941
glomerular visceral epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Basp1 brain abundant membrane attached signal protein 1 JBrowse link NW_004955426 6,149,756 6,193,222 RGD:9068941
G Cd24 CD24 molecule JBrowse link NW_004955411 32,270,881 32,275,236 RGD:9068941
G Ext1 exostosin glycosyltransferase 1 JBrowse link NW_004955417 23,798,044 24,067,759 RGD:9068941
G Klf15 Kruppel like factor 15 JBrowse link NW_004955421 21,609,709 21,618,920 RGD:9068941
G Prom1 prominin 1 JBrowse link NW_004955480 7,955,501 8,059,537 RGD:9068941
G Ptpro protein tyrosine phosphatase receptor type O JBrowse link NW_004955413 12,019,026 12,248,026 RGD:9068941
G Wt1 WT1 transcription factor JBrowse link NW_004955476 10,464,688 10,504,473 RGD:9068941
glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link NW_004955410 20,428,531 20,459,482 RGD:9068941
G Ctnnd1 catenin delta 1 JBrowse link NW_004955511 2,658,879 2,705,992 RGD:9068941
G Kirrel3 kirre like nephrin family adhesion molecule 3 JBrowse link NW_004955412 27,428,360 27,994,458 RGD:9068941
G Mef2c myocyte enhancer factor 2C JBrowse link NW_004955418 22,537,388 22,701,434 RGD:9068941
G Mtss1 MTSS I-BAR domain containing 1 JBrowse link NW_004955540 3,204,357 3,346,026 RGD:9068941
glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angpt1 angiopoietin 1 JBrowse link NW_004955417 30,199,508 30,386,695 RGD:9068941
G Angpt2 angiopoietin 2 JBrowse link NW_004955403 54,139,823 54,193,740 RGD:9068941
G Hes1 hes family bHLH transcription factor 1 JBrowse link NW_004955420 14,565,921 14,568,447 RGD:9068941
G Tek TEK receptor tyrosine kinase JBrowse link NW_004955472 7,633,790 7,748,130 RGD:9068941
metanephric glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link NW_004955532 1,115,412 1,127,264 RGD:9068941
metanephric glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfra platelet derived growth factor receptor alpha JBrowse link NW_004955447 16,570,652 16,613,410 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:9068941
G Tcf21 transcription factor 21 JBrowse link NW_004955439 2,617,562 2,620,613 RGD:9068941
metanephric glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 molecule JBrowse link NW_004955406 43,116,688 43,130,405 RGD:9068941
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:9068941
metanephric glomerular mesangium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:9068941
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link NW_004955532 1,115,412 1,127,264 RGD:9068941
G Nphs2 NPHS2 stomatin family member, podocin JBrowse link NW_004955406 18,862,054 18,885,214 RGD:9068941
metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link NW_004955476 6,611,102 6,629,294 RGD:9068941
G Lhx1 LIM homeobox 1 JBrowse link NW_004955451 1,037,936 1,048,501 RGD:9068941
metanephric glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:9068941
metanephric glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp1 aquaporin 1 (Colton blood group) JBrowse link NW_004955410 32,066,196 32,078,661 RGD:9068941
G Osr1 odd-skipped related transcription factor 1 JBrowse link NW_004955469 1,954,470 1,961,344 RGD:9068941
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
G Bmp7 bone morphogenetic protein 7 JBrowse link NW_004955445 2,154,057 2,235,594 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
negative regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wt1 WT1 transcription factor JBrowse link NW_004955476 10,464,688 10,504,473 RGD:9068941
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3ar1 complement C3a receptor 1 JBrowse link NW_004955413 6,707,003 6,715,689 RGD:9068941
G Cflar CASP8 and FADD like apoptosis regulator JBrowse link NW_004955403 415,092 442,214 RGD:9068941
G Il6r interleukin 6 receptor JBrowse link NW_004955545 932,814 979,359 RGD:9068941
G Itgb3 integrin subunit beta 3 JBrowse link NW_004955478 9,788,192 9,830,254 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941
G Pdgfd platelet derived growth factor D JBrowse link NW_004955412 6,868,995 7,093,353 RGD:9068941
G Serpinb7 serpin family B member 7 JBrowse link NW_004955402 47,599,503 47,649,537 RGD:9068941
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link NW_004955418 2,001,509 2,005,269 RGD:9068941
positive regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nog noggin JBrowse link NW_004955451 6,192,368 6,193,766 RGD:9068941
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link NW_004955420 20,911,181 20,922,992 RGD:9068941
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor type 2 JBrowse link NW_004955534 3,653,112 3,654,248 RGD:9068941
G Pax2 paired box 2 JBrowse link NW_004955485 9,351,913 9,430,607 RGD:9068941
G Ret ret proto-oncogene JBrowse link NW_004955546 1,221,995 1,252,147 RGD:9068941
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfa platelet derived growth factor subunit A JBrowse link NW_004955460 8,328,400 8,346,755 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11825
    developmental process 5546
      anatomical structure development 5188
        glomerulus development 69
          glomerular basement membrane development + 11
          glomerular epithelium development + 23
          glomerulus morphogenesis + 11
          glomerulus vasculature development + 29
          mesonephric glomerulus development + 0
          metanephric glomerulus development + 17
          negative regulation of glomerulus development + 4
          positive regulation of glomerulus development + 13
          pronephric glomerulus development + 0
          regulation of glomerulus development + 18
Path 2
Term Annotations click to browse term
  biological_process 11825
    developmental process 5546
      anatomical structure development 5188
        multicellular organism development 4754
          system development 4497
            urogenital system development 400
              renal system development 353
                kidney development 339
                  nephron development 159
                    glomerulus development 69
                      glomerular basement membrane development + 11
                      glomerular epithelium development + 23
                      glomerulus morphogenesis + 11
                      glomerulus vasculature development + 29
                      mesonephric glomerulus development + 0
                      metanephric glomerulus development + 17
                      negative regulation of glomerulus development + 4
                      positive regulation of glomerulus development + 13
                      pronephric glomerulus development + 0
                      regulation of glomerulus development + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.