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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerulus development
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Accession:GO:0032835 term browser browse the term
Definition:The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.
Synonyms:exact_synonym: glomerular development


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glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2 BCL2 apoptosis regulator JBrowse link 1 13,733,849 13,900,653 RGD:13508589
G C5 complement C5 JBrowse link 11 73,953,727 74,029,919 RGD:9068941
G CFH complement factor H JBrowse link 38 2,878,677 2,956,226 RGD:9068941
G ENPEP glutamyl aminopeptidase JBrowse link 32 30,553,055 30,639,790 RGD:13508589
G PLCE1 phospholipase C epsilon 1 JBrowse link 28 8,209,707 8,484,427 RGD:13508589
G PTPRO protein tyrosine phosphatase receptor type O JBrowse link 27 31,082,334 31,322,024 RGD:13508589
G TCF21 transcription factor 21 JBrowse link 1 26,856,281 26,859,654 RGD:13508589
G WT1 WT1 transcription factor JBrowse link 18 35,099,660 35,148,767 RGD:9068941
G WWTR1 WW domain containing transcription regulator 1 JBrowse link 23 44,277,707 44,409,911 RGD:13508589
glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G COL4A3 collagen type IV alpha 3 chain JBrowse link 25 39,975,547 40,106,833 RGD:13508589
G COL4A4 collagen type IV alpha 4 chain JBrowse link 25 39,849,680 39,976,035 RGD:13508589
G EXT1 exostosin glycosyltransferase 1 JBrowse link 13 17,172,497 17,457,084 RGD:9068941
G MPV17 mitochondrial inner membrane protein MPV17 JBrowse link 17 21,280,523 21,290,967 RGD:9068941
G MYO1E myosin IE JBrowse link 30 24,067,622 24,265,567 RGD:13508589
G NID1 nidogen 1 JBrowse link 4 3,935,218 4,018,133 RGD:9068941
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 1 116,794,891 116,814,418 RGD:13508589
G SULF1 sulfatase 1 JBrowse link 29 18,709,406 18,885,248 RGD:13508589
G SULF2 sulfatase 2 JBrowse link 24 34,732,000 34,850,347 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 18 35,099,660 35,148,767 RGD:9068941
glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 8 29,997,563 30,254,307 RGD:13508589
G NOTCH2 notch receptor 2 JBrowse link 17 56,854,825 57,020,157 RGD:13508589
G NOTCH3 notch receptor 3 JBrowse link 20 46,946,654 46,978,821 RGD:13508589
glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD34 CD34 molecule JBrowse link 7 6,734,363 6,747,991 RGD:13508589
G FOXC2 forkhead box C2 JBrowse link 5 66,234,336 66,296,007 RGD:13508589
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 9 12,166,124 12,219,553 RGD:13508589
glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTA2 actin alpha 2, smooth muscle JBrowse link 26 38,700,434 38,714,915 RGD:13508589
G FOXC2 forkhead box C2 JBrowse link 5 66,234,336 66,296,007 RGD:13508589
G GPR4 G protein-coupled receptor 4 JBrowse link 1 109,963,001 109,974,798 RGD:9068941
G NOTCH1 notch receptor 1 JBrowse link 9 48,975,972 49,018,985 RGD:13508589
glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGR1 early growth response 1 JBrowse link 11 26,046,195 26,049,806 RGD:9068941
glomerular parietal epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXJ1 forkhead box J1 JBrowse link 9 4,512,898 4,517,764 RGD:13508589
glomerular parietal epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PROM1 prominin 1 JBrowse link 3 64,229,487 64,362,346 RGD:9068941
glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AMPD2 adenosine monophosphate deaminase 2 JBrowse link 6 42,239,809 42,251,704 RGD:9068941
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 24 21,725,126 21,804,745 RGD:9068941
G BMP4 bone morphogenetic protein 4 JBrowse link 8 29,997,563 30,254,307 RGD:13508589
G IQGAP1 IQ motif containing GTPase activating protein 1 JBrowse link 3 53,683,869 53,791,136 RGD:13508589
G JAG1 jagged canonical Notch ligand 1 JBrowse link 24 11,656,926 11,693,146 RGD:13508589
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 18 17,973,058 19,098,785 RGD:9068941
G MYO1E myosin IE JBrowse link 30 24,067,622 24,265,567 RGD:13508589
G NOTCH2 notch receptor 2 JBrowse link 17 56,854,825 57,020,157 RGD:13508589
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 1 116,794,891 116,814,418 RGD:13508589
G PODXL podocalyxin like JBrowse link 14 5,614,006 5,625,360 RGD:13508589
G WT1 WT1 transcription factor JBrowse link 18 35,099,660 35,148,767 RGD:9068941
glomerular visceral epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BASP1 brain abundant membrane attached signal protein 1 JBrowse link 4 86,360,641 86,417,408 RGD:13508589
G EXT1 exostosin glycosyltransferase 1 JBrowse link 13 17,172,497 17,457,084 RGD:9068941
G FOXC2 forkhead box C2 JBrowse link 5 66,234,336 66,296,007 RGD:13508589
G KLF15 Kruppel like factor 15 JBrowse link 20 513,649 524,873 RGD:13508589
G PROM1 prominin 1 JBrowse link 3 64,229,487 64,362,346 RGD:9068941
G PTPRO protein tyrosine phosphatase receptor type O JBrowse link 27 31,082,334 31,322,024 RGD:13508589
G WT1 WT1 transcription factor JBrowse link 18 35,099,660 35,148,767 RGD:9068941
glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 14 31,743,704 31,793,484 RGD:9068941
G KIRREL3 kirre like nephrin family adhesion molecule 3 JBrowse link 5 7,583,530 8,124,045 RGD:9068941
G MEF2C myocyte enhancer factor 2C JBrowse link 3 19,778,997 19,948,203 RGD:13508589
G MTSS1 MTSS I-BAR domain containing 1 JBrowse link 13 22,633,001 22,794,960 RGD:13508589
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 JBrowse link 18 38,497,649 38,522,728 RGD:9068941
glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANGPT1 angiopoietin 1 JBrowse link 13 8,068,920 8,312,090 RGD:9068941
G ANGPT2 angiopoietin 2 JBrowse link 16 58,404,049 58,458,344 RGD:9068941
G TEK TEK receptor tyrosine kinase JBrowse link 11 45,278,375 45,377,300 RGD:9068941
metanephric glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LAMB2 laminin subunit beta 2 JBrowse link 20 40,036,967 40,062,628 RGD:13508589
metanephric glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRA platelet derived growth factor receptor alpha JBrowse link 13 46,729,722 46,775,828 RGD:13508589
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:13508589
G TCF21 transcription factor 21 JBrowse link 1 26,856,281 26,859,654 RGD:13508589
metanephric glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B JBrowse link 10 25,798,877 25,819,422 RGD:9068941
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B JBrowse link 10 25,798,877 25,819,422 RGD:13508589
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD34 CD34 molecule JBrowse link 7 6,734,363 6,747,991 RGD:13508589
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B JBrowse link 10 25,798,877 25,819,422 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:13508589
metanephric glomerular mesangium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:9068941
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LAMB2 laminin subunit beta 2 JBrowse link 20 40,036,967 40,062,628 RGD:13508589
G NPHS2 NPHS2 stomatin family member, podocin JBrowse link 7 20,347,526 20,375,975 RGD:13508589
metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link 21 47,952,019 47,995,530 RGD:9068941
G LHX1 LIM homeobox 1 JBrowse link 9 36,760,890 36,768,345 RGD:9068941
metanephric glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:9068941
metanephric glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AQP1 aquaporin 1 (Colton blood group) JBrowse link 14 43,592,266 43,603,903 RGD:9068941
G OSR1 odd-skipped related transcription factor 1 JBrowse link 17 14,508,543 14,515,657 RGD:13508589
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 8 29,997,563 30,254,307 RGD:13508589
G BMP7 bone morphogenetic protein 7 JBrowse link 24 42,203,183 42,294,105 RGD:13508589
G IFNG interferon gamma JBrowse link 10 10,406,866 10,411,698 RGD:9068941
negative regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 8 29,997,563 30,254,307 RGD:9068941
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WT1 WT1 transcription factor JBrowse link 18 35,099,660 35,148,767 RGD:9068941
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3AR1 complement C3a receptor 1 JBrowse link 27 37,431,745 37,439,858 RGD:9068941
G CFLAR CASP8 and FADD like apoptosis regulator JBrowse link 37 10,268,407 10,307,803 RGD:9068941
G IL6R interleukin 6 receptor JBrowse link 7 42,877,731 42,920,149 RGD:13508589
G ITGB3 integrin subunit beta 3 JBrowse link 9 9,179,667 9,231,061 RGD:9068941
G PDGFB platelet derived growth factor subunit B JBrowse link 10 25,798,877 25,819,422 RGD:13508589
G PDGFD platelet derived growth factor D JBrowse link 5 27,863,739 28,092,376 RGD:9068941
G SERPINB7 serpin family B member 7 JBrowse link 1 13,336,067 13,392,674 RGD:9068941
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGR1 early growth response 1 JBrowse link 11 26,046,195 26,049,806 RGD:9068941
positive regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NOG noggin JBrowse link 9 31,453,604 31,456,060 RGD:9068941
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:9068941
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTR2 angiotensin II receptor type 2 JBrowse link X 88,703,551 88,708,451 RGD:13508589
G PAX2 paired box 2 JBrowse link 28 13,442,894 13,519,853 RGD:9068941
G RET ret proto-oncogene JBrowse link 28 3,946,132 3,995,505 RGD:9068941
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFA platelet derived growth factor subunit A JBrowse link 6 16,271,082 16,293,246 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16042
    developmental process 6212
      anatomical structure development 5762
        glomerulus development 69
          glomerular basement membrane development + 11
          glomerular epithelium development + 24
          glomerulus morphogenesis + 11
          glomerulus vasculature development + 29
          mesonephric glomerulus development + 0
          metanephric glomerulus development + 17
          negative regulation of glomerulus development + 4
          positive regulation of glomerulus development + 13
          pronephric glomerulus development + 0
          regulation of glomerulus development + 18
Path 2
Term Annotations click to browse term
  biological_process 16042
    developmental process 6212
      anatomical structure development 5762
        multicellular organism development 5250
          system development 4915
            urogenital system development 414
              renal system development 366
                kidney development 353
                  nephron development 161
                    glomerulus development 69
                      glomerular basement membrane development + 11
                      glomerular epithelium development + 24
                      glomerulus morphogenesis + 11
                      glomerulus vasculature development + 29
                      mesonephric glomerulus development + 0
                      metanephric glomerulus development + 17
                      negative regulation of glomerulus development + 4
                      positive regulation of glomerulus development + 13
                      pronephric glomerulus development + 0
                      regulation of glomerulus development + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.