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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerulus development
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Accession:GO:0032835 term browser browse the term
Definition:The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.
Synonyms:exact_synonym: glomerular development


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glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:2290270
G Cfh complement component factor h JBrowse link 1 140,085,855 140,183,411 RGD:2290270
G Enpep glutamyl aminopeptidase JBrowse link 3 129,269,177 129,332,749 RGD:2290270
G Hc hemolytic complement JBrowse link 2 34,983,329 35,068,506 RGD:2290270
G Heyl hairy/enhancer-of-split related with YRPW motif-like JBrowse link 4 123,233,556 123,249,870 RGD:2290270
G Plce1 phospholipase C, epsilon 1 JBrowse link 19 38,481,034 38,785,105 RGD:2290270
G Ptpro protein tyrosine phosphatase, receptor type, O JBrowse link 6 137,252,299 137,464,634 RGD:2290270
G Tcf21 transcription factor 21 JBrowse link 10 22,817,263 22,820,143 RGD:2290270
G Vangl2 VANGL planar cell polarity 2 JBrowse link 1 172,000,960 172,027,318 RGD:2290270
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:2290270
G Wwtr1 WW domain containing transcription regulator 1 JBrowse link 3 57,455,644 57,575,910 RGD:2290270
glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col4a3 collagen, type IV, alpha 3 JBrowse link 1 82,586,921 82,722,059 RGD:2290270
G Col4a4 collagen, type IV, alpha 4 JBrowse link 1 82,448,419 82,587,034 RGD:2290270
G Ext1 exostosin glycosyltransferase 1 JBrowse link 15 53,068,261 53,346,183 RGD:2290270
G Mpv17 MpV17 mitochondrial inner membrane protein JBrowse link 5 31,140,663 31,154,251 RGD:2290270
G Myo1e myosin IE JBrowse link 9 70,207,350 70,400,067 RGD:2290270
G Nid1 nidogen 1 JBrowse link 13 13,437,602 13,512,275 RGD:2290270
G Nphs1 nephrosis 1, nephrin JBrowse link 7 30,458,207 30,488,623 RGD:9068941
G Sulf1 sulfatase 1 JBrowse link 1 12,692,197 12,861,192 RGD:2290270
G Sulf2 sulfatase 2 JBrowse link 2 166,073,899 166,155,683 RGD:2290270
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:2290270
glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Notch2 notch 2 JBrowse link 3 98,013,538 98,150,367 RGD:2290270
G Notch3 notch 3 JBrowse link 17 32,120,820 32,166,896 RGD:2290270
glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 antigen JBrowse link 1 194,938,821 194,961,292 RGD:9068941
G Foxc2 forkhead box C2 JBrowse link 8 121,116,171 121,118,895 RGD:2290270
G Pecam1 platelet/endothelial cell adhesion molecule 1 JBrowse link 11 106,654,213 106,715,281 RGD:9068941
glomerular epithelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxc1 forkhead box C1 JBrowse link 13 31,806,646 31,810,635 RGD:2290270
glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin, alpha 2, smooth muscle, aorta JBrowse link 19 34,240,336 34,255,585 RGD:9068941
G Foxc2 forkhead box C2 JBrowse link 8 121,116,171 121,118,895 RGD:2290270
G Gpr4 G protein-coupled receptor 4 JBrowse link 7 19,212,538 19,224,176 RGD:2290270
G Notch1 notch 1 JBrowse link 2 26,457,902 26,503,822 RGD:2290270
glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link 18 34,861,207 34,864,956 RGD:2290270
glomerular parietal epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 11 116,330,704 116,335,499 RGD:9068941
glomerular parietal epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24a CD24a antigen JBrowse link 10 43,579,169 43,584,265 RGD:9068941
G Prom1 prominin 1 JBrowse link 5 43,993,621 44,102,047 RGD:2290270
glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ampd2 adenosine monophosphate deaminase 2 JBrowse link 3 108,074,059 108,086,687 RGD:2290270
G Asxl1 additional sex combs like 1 JBrowse link 2 153,345,830 153,404,007 RGD:2290270
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Jag1 jagged 1 JBrowse link 2 137,081,451 137,116,520 RGD:2290270
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 5 19,219,387 20,704,792 RGD:9068941
G Myo1e myosin IE JBrowse link 9 70,207,350 70,400,067 RGD:2290270
G Notch2 notch 2 JBrowse link 3 98,013,538 98,150,367 RGD:2290270
G Nphs1 nephrosis 1, nephrin JBrowse link 7 30,458,207 30,488,623 RGD:9068941
G Podxl podocalyxin-like JBrowse link 6 31,519,493 31,563,937 RGD:9068941
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:2290270
glomerular visceral epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Basp1 brain abundant, membrane attached signal protein 1 JBrowse link 15 25,363,277 25,413,764 RGD:2290270
G Cd24a CD24a antigen JBrowse link 10 43,579,169 43,584,265 RGD:9068941
G Ext1 exostosin glycosyltransferase 1 JBrowse link 15 53,068,261 53,346,183 RGD:2290270
G Foxc2 forkhead box C2 JBrowse link 8 121,116,171 121,118,895 RGD:2290270
G Klf15 Kruppel-like factor 15 JBrowse link 6 90,461,043 90,491,803 RGD:2290270
G Prom1 prominin 1 JBrowse link 5 43,993,621 44,102,047 RGD:2290270
G Ptpro protein tyrosine phosphatase, receptor type, O JBrowse link 6 137,252,299 137,464,634 RGD:2290270
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:2290270
glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:2290270
G Ctnnd1 catenin (cadherin associated protein), delta 1 JBrowse link 2 84,587,096 84,658,977 RGD:2290270
G Kirrel3 kirre like nephrin family adhesion molecule 3 JBrowse link 9 34,485,853 35,040,807 RGD:2290270
G Mef2c myocyte enhancer factor 2C JBrowse link 13 83,504,017 83,667,079 RGD:2290270
G Mtss1 MTSS I-BAR domain containing 1 JBrowse link 15 58,941,234 59,083,956 RGD:2290270
glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angpt1 angiopoietin 1 JBrowse link 15 42,424,667 42,676,977 RGD:2290270
G Angpt2 angiopoietin 2 JBrowse link 8 18,690,263 18,741,562 RGD:2290270
G Hes1 hes family bHLH transcription factor 1 JBrowse link 16 30,065,357 30,067,796 RGD:2290270
G Tek TEK receptor tyrosine kinase JBrowse link 4 94,739,086 94,874,976 RGD:2290270
metanephric glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin, beta 2 JBrowse link 9 108,479,847 108,490,530 RGD:2290270
metanephric glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfra platelet derived growth factor receptor, alpha polypeptide JBrowse link 5 75,151,322 75,198,206 RGD:2290270
G Pdgfrb platelet derived growth factor receptor, beta polypeptide JBrowse link 18 61,045,127 61,085,067 RGD:2290270
G Tcf21 transcription factor 21 JBrowse link 10 22,817,263 22,820,143 RGD:2290270
metanephric glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor, B polypeptide JBrowse link 15 79,995,865 80,024,614 RGD:2290270
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor, B polypeptide JBrowse link 15 79,995,865 80,024,614 RGD:2290270
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 antigen JBrowse link 1 194,938,821 194,961,292 RGD:9068941
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor, B polypeptide JBrowse link 15 79,995,865 80,024,614 RGD:2290270
G Pdgfrb platelet derived growth factor receptor, beta polypeptide JBrowse link 18 61,045,127 61,085,067 RGD:2290270
metanephric glomerular mesangium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor, beta polypeptide JBrowse link 18 61,045,127 61,085,067 RGD:2290270
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin, beta 2 JBrowse link 9 108,479,847 108,490,530 RGD:2290270
G Nphs2 nephrosis 2, podocin JBrowse link 1 156,310,535 156,328,035 RGD:9068941
metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 JBrowse link 2 109,917,647 110,014,257 RGD:2290270
G Lhx1 LIM homeobox protein 1 JBrowse link 11 84,517,975 84,525,534 RGD:9068941
metanephric glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor, beta polypeptide JBrowse link 18 61,045,127 61,085,067 RGD:9068941
metanephric glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp1 aquaporin 1 JBrowse link 6 55,336,299 55,348,555 RGD:2290270
G Osr1 odd-skipped related transcription factor 1 JBrowse link 12 9,574,442 9,581,500 RGD:2290270
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Bmp7 bone morphogenetic protein 7 JBrowse link 2 172,868,012 172,940,321 RGD:2290270
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:2290270
negative regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:2290270
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3ar1 complement component 3a receptor 1 JBrowse link 6 122,847,140 122,856,157 RGD:2290270
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 1 58,711,311 58,758,884 RGD:2290270
G Il6ra interleukin 6 receptor, alpha JBrowse link 3 89,869,324 89,913,196 RGD:2290270
G Itgb3 integrin beta 3 JBrowse link 11 104,608,000 104,670,476 RGD:2290270
G Pdgfb platelet derived growth factor, B polypeptide JBrowse link 15 79,995,865 80,024,614 RGD:2290270
G Pdgfd platelet-derived growth factor, D polypeptide JBrowse link 9 6,168,363 6,534,284 RGD:2290270
G Serpinb7 serine (or cysteine) peptidase inhibitor, clade B, member 7 JBrowse link 1 107,422,689 107,452,689 RGD:2290270
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link 18 34,861,207 34,864,956 RGD:2290270
positive regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nog noggin JBrowse link 11 89,300,638 89,302,559 RGD:2290270
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 16 23,146,536 23,157,968 RGD:2290270
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 21,484,624 21,488,833 RGD:2290270
G Pax2 paired box 2 JBrowse link 19 44,746,601 44,838,269 RGD:2290270
G Ret ret proto-oncogene JBrowse link 6 118,151,748 118,197,744 RGD:2290270
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfa platelet derived growth factor, alpha JBrowse link 5 138,976,014 139,000,792 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23163
    developmental process 6947
      anatomical structure development 6420
        glomerulus development 73
          glomerular basement membrane development + 11
          glomerular epithelium development + 25
          glomerulus morphogenesis + 11
          glomerulus vasculature development + 30
          mesonephric glomerulus development + 0
          metanephric glomerulus development + 17
          negative regulation of glomerulus development + 4
          positive regulation of glomerulus development + 13
          pronephric glomerulus development + 0
          regulation of glomerulus development + 18
Path 2
Term Annotations click to browse term
  biological_process 23163
    developmental process 6947
      anatomical structure development 6420
        multicellular organism development 5888
          system development 5326
            urogenital system development 435
              renal system development 386
                kidney development 372
                  nephron development 166
                    glomerulus development 73
                      glomerular basement membrane development + 11
                      glomerular epithelium development + 25
                      glomerulus morphogenesis + 11
                      glomerulus vasculature development + 30
                      mesonephric glomerulus development + 0
                      metanephric glomerulus development + 17
                      negative regulation of glomerulus development + 4
                      positive regulation of glomerulus development + 13
                      pronephric glomerulus development + 0
                      regulation of glomerulus development + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.