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ONTOLOGY REPORT - ANNOTATIONS


Term:glomerulus development
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Accession:GO:0032835 term browser browse the term
Definition:The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.
Synonyms:exact_synonym: glomerular development


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glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2 BCL2 apoptosis regulator JBrowse link 1 158,337,403 158,518,214 RGD:9068941
G C5 complement C5 JBrowse link 1 260,995,662 261,088,868 RGD:9068941
G CFH complement factor H RGD:9068941
G ENPEP glutamyl aminopeptidase JBrowse link 8 111,765,839 111,858,349 RGD:9068941
G HEYL hes related family bHLH transcription factor with YRPW motif like JBrowse link 6 95,442,655 95,459,597 RGD:14298760
G PLCE1 phospholipase C epsilon 1 JBrowse link 14 105,422,628 105,764,736 RGD:14298760
G PTPRO protein tyrosine phosphatase receptor type O JBrowse link 5 57,021,819 57,263,395 RGD:9068941
G TCF21 transcription factor 21 JBrowse link 1 29,975,280 29,978,273 RGD:14298760
G VANGL2 VANGL planar cell polarity protein 2 JBrowse link 4 90,051,994 90,080,701 RGD:14298760
G WT1 WT1 transcription factor JBrowse link 2 28,411,467 28,456,007 RGD:14298760
G WWTR1 WW domain containing transcription regulator 1 JBrowse link 13 89,742,980 89,889,547 RGD:14298760
glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G COL4A3 collagen type IV alpha 3 chain JBrowse link 15 128,611,640 128,763,331 RGD:14298760
G COL4A4 collagen type IV alpha 4 chain JBrowse link 15 128,472,228 128,612,302 RGD:14298760
G EXT1 exostosin glycosyltransferase 1 JBrowse link 4 20,645,002 20,935,769 RGD:9068941
G MPV17 mitochondrial inner membrane protein MPV17 JBrowse link 3 111,823,075 111,833,929 RGD:9068941
G MYO1E myosin IE JBrowse link 1 112,677,545 112,902,005 RGD:14298760
G NID1 nidogen 1 JBrowse link 14 55,239,327 55,346,948 RGD:14298760
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 6 45,248,325 45,271,892 RGD:14298760
G SULF1 sulfatase 1 JBrowse link 4 65,595,947 65,778,889 RGD:14298760
G SULF2 sulfatase 2 JBrowse link 17 49,663,721 49,805,118 RGD:14298760
G WT1 WT1 transcription factor JBrowse link 2 28,411,467 28,456,007 RGD:14298760
glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 1 183,415,989 183,422,888 RGD:14298760
G NOTCH2 notch receptor 2 JBrowse link 4 100,951,522 101,152,348 RGD:14298760
G NOTCH3 notch receptor 3 JBrowse link 2 62,364,507 62,402,348 RGD:14298760
glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD34 CD34 molecule JBrowse link 9 134,912,793 134,937,763 RGD:14298760
G FOXC2 forkhead box C2 JBrowse link 6 2,552,141 2,555,041 RGD:14298760
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 12 14,667,643 14,723,296 RGD:14298760
glomerular epithelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXC1 forkhead box C1 JBrowse link 7 837,088 840,593 RGD:14298760
glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTA2 actin alpha 2, smooth muscle JBrowse link 14 100,868,145 100,886,732 RGD:14298760
G FOXC2 forkhead box C2 JBrowse link 6 2,552,141 2,555,041 RGD:14298760
G GPR4 G protein-coupled receptor 4 JBrowse link 6 51,968,310 51,979,931 RGD:9068941
G NOTCH1 notch receptor 1 RGD:14298760
glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGR1 early growth response 1 JBrowse link 2 140,440,829 140,445,302 RGD:9068941
glomerular parietal epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXJ1 forkhead box J1 JBrowse link 12 5,307,370 5,312,117 RGD:14298760
glomerular parietal epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100519934 uncharacterized LOC100519934 JBrowse link 1 73,119,758 73,124,368 RGD:9068941
G PROM1 prominin 1 JBrowse link 8 11,215,659 11,331,442 RGD:14298760
glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AMPD2 adenosine monophosphate deaminase 2 JBrowse link 4 110,493,490 110,505,123 RGD:9068941
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 17 35,985,978 36,067,122 RGD:14298760
G BMP4 bone morphogenetic protein 4 JBrowse link 1 183,415,989 183,422,888 RGD:14298760
G JAG1 jagged canonical Notch ligand 1 JBrowse link 17 19,591,248 19,629,659 RGD:14298760
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 9 100,846,693 102,171,199 RGD:9068941
G MYO1E myosin IE JBrowse link 1 112,677,545 112,902,005 RGD:14298760
G NOTCH2 notch receptor 2 JBrowse link 4 100,951,522 101,152,348 RGD:14298760
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 6 45,248,325 45,271,892 RGD:14298760
G PODXL podocalyxin like JBrowse link 18 17,444,339 17,494,507 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 2 28,411,467 28,456,007 RGD:9068941
glomerular visceral epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BASP1 brain abundant membrane attached signal protein 1 JBrowse link 16 6,384,322 6,440,507 RGD:14298760
G EXT1 exostosin glycosyltransferase 1 JBrowse link 4 20,645,002 20,935,769 RGD:9068941
G FOXC2 forkhead box C2 JBrowse link 6 2,552,141 2,555,041 RGD:14298760
G KLF15 Kruppel like factor 15 JBrowse link 7 53,877,813 53,890,558 RGD:14298760
G LOC100519934 uncharacterized LOC100519934 JBrowse link 1 73,119,758 73,124,368 RGD:9068941
G PROM1 prominin 1 JBrowse link 8 11,215,659 11,331,442 RGD:14298760
G PTPRO protein tyrosine phosphatase receptor type O JBrowse link 5 57,021,819 57,263,395 RGD:14298760
G WT1 WT1 transcription factor JBrowse link 2 28,411,467 28,456,007 RGD:14298760
glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 9 86,511,866 86,555,950 RGD:9068941
G CTNND1 catenin delta 1 JBrowse link 2 13,143,604 13,209,251 RGD:9068941
G KIRREL3 kirre like nephrin family adhesion molecule 3 JBrowse link 9 53,493,735 54,066,490 RGD:14298760
G MEF2C myocyte enhancer factor 2C JBrowse link 2 96,122,407 96,296,927 RGD:14298760
G MTSS1 MTSS I-BAR domain containing 1 JBrowse link 4 14,933,290 15,103,256 RGD:9068941
glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANGPT1 angiopoietin 1 JBrowse link 4 29,925,203 30,233,434 RGD:14298760
G ANGPT2 angiopoietin 2 JBrowse link 15 37,544,177 37,600,925 RGD:9068941
G HES1 hes family bHLH transcription factor 1 JBrowse link 13 131,135,970 131,137,865 RGD:14298760
G TEK TEK receptor tyrosine kinase JBrowse link 1 195,938,177 196,052,294 RGD:9068941
metanephric glomerular basement membrane development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LAMB2 laminin subunit beta 2 JBrowse link 13 31,738,282 31,750,623 RGD:14298760
metanephric glomerular capillary formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRA platelet derived growth factor receptor alpha JBrowse link 8 40,966,568 41,021,440 RGD:14298760
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:14298760
G TCF21 transcription factor 21 JBrowse link 1 29,975,280 29,978,273 RGD:14298760
metanephric glomerular endothelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B RGD:9068941
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B RGD:9068941
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD34 CD34 molecule JBrowse link 9 134,912,793 134,937,763 RGD:14298760
metanephric glomerular mesangial cell proliferation involved in metanephros development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFB platelet derived growth factor subunit B RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:14298760
metanephric glomerular mesangium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:9068941
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LAMB2 laminin subunit beta 2 JBrowse link 13 31,738,282 31,750,623 RGD:14298760
G NPHS2 NPHS2 stomatin family member, podocin JBrowse link 9 121,217,734 121,236,214 RGD:14298760
metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link 2 32,871,837 32,979,150 RGD:14298760
G LHX1 LIM homeobox 1 JBrowse link 12 38,450,708 38,457,583 RGD:9068941
metanephric glomerulus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:9068941
metanephric glomerulus vasculature development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AQP1 aquaporin 1 (Colton blood group) JBrowse link 18 42,063,482 42,076,741 RGD:9068941
G OSR1 odd-skipped related transcription factor 1 JBrowse link 3 118,368,471 118,765,107 RGD:14298760
negative regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 1 183,415,989 183,422,888 RGD:14298760
G BMP7 bone morphogenetic protein 7 JBrowse link 17 57,567,770 57,676,516 RGD:9068941
G IFNG interferon gamma JBrowse link 5 32,477,906 32,482,670 RGD:9068941
negative regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 1 183,415,989 183,422,888 RGD:9068941
negative regulation of metanephric glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WT1 WT1 transcription factor JBrowse link 2 28,411,467 28,456,007 RGD:14298760
positive regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3AR1 complement C3a receptor 1 JBrowse link 5 63,088,778 63,098,750 RGD:9068941
G CFLAR CASP8 and FADD like apoptosis regulator JBrowse link 15 104,780,744 104,835,631 RGD:9068941
G IL6R interleukin 6 receptor JBrowse link 4 95,322,426 95,381,393 RGD:9068941
G ITGB3 integrin subunit beta 3 JBrowse link 12 16,694,466 16,752,228 RGD:9068941
G PDGFB platelet derived growth factor subunit B RGD:14298760
G PDGFD platelet derived growth factor D JBrowse link 9 34,388,636 34,621,227 RGD:9068941
G SERPINB7 serpin family B member 7 JBrowse link 1 157,953,872 157,999,242 RGD:9068941
positive regulation of glomerular metanephric mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGR1 early growth response 1 JBrowse link 2 140,440,829 140,445,302 RGD:9068941
positive regulation of glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NOG noggin JBrowse link 12 32,891,321 32,892,206 RGD:14298760
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 13 124,633,906 124,646,237 RGD:14298760
positive regulation of metanephric glomerulus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTR2 angiotensin II receptor type 2 JBrowse link X 95,267,709 95,272,237 RGD:14298760
G PAX2 paired box 2 JBrowse link 14 111,822,334 111,914,950 RGD:9068941
G RET ret proto-oncogene JBrowse link 14 61,305,818 61,361,416 RGD:14298760
regulation of glomerular mesangial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFA platelet derived growth factor subunit A JBrowse link 3 296,399 322,967 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16411
    developmental process 6234
      anatomical structure development 5775
        glomerulus development 73
          glomerular basement membrane development + 11
          glomerular epithelium development + 25
          glomerulus morphogenesis + 11
          glomerulus vasculature development + 30
          mesonephric glomerulus development + 0
          metanephric glomerulus development + 17
          negative regulation of glomerulus development + 4
          positive regulation of glomerulus development + 13
          pronephric glomerulus development + 0
          regulation of glomerulus development + 18
Path 2
Term Annotations click to browse term
  biological_process 16411
    developmental process 6234
      anatomical structure development 5775
        multicellular organism development 5262
          system development 4908
            urogenital system development 421
              renal system development 371
                kidney development 358
                  nephron development 165
                    glomerulus development 73
                      glomerular basement membrane development + 11
                      glomerular epithelium development + 25
                      glomerulus morphogenesis + 11
                      glomerulus vasculature development + 30
                      mesonephric glomerulus development + 0
                      metanephric glomerulus development + 17
                      negative regulation of glomerulus development + 4
                      positive regulation of glomerulus development + 13
                      pronephric glomerulus development + 0
                      regulation of glomerulus development + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.