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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to insulin stimulus
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Accession:GO:0032869 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.


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cellular response to insulin stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl5 acyl-CoA synthetase long-chain family member 5 JBrowse link 1 276,240,703 276,290,012 RGD:2312808
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:1599808
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686346
RGD:1600115
RGD:1624291
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:1626076
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
RGD:8553574
RGD:8553650
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:1624291
RGD:8553574
G Akt3 AKT serine/threonine kinase 3 JBrowse link 13 95,076,308 95,348,913 RGD:8553574
G Alas1 5'-aminolevulinate synthase 1 JBrowse link 8 114,927,704 114,941,038 RGD:4144187
G Aldob aldolase, fructose-bisphosphate B JBrowse link 5 64,805,772 64,818,813 RGD:1599069
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 JBrowse link 4 155,386,367 155,414,034 RGD:1626288
G Aprt adenine phosphoribosyl transferase JBrowse link 19 55,387,288 55,389,256 RGD:2316798
G C2cd5 C2 calcium-dependent domain containing 5 JBrowse link 4 177,245,868 177,331,910 RGD:1624291
G Capn10 calpain 10 JBrowse link 9 100,104,000 100,112,833 RGD:1624291
RGD:1600115
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549642
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:1582339
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:2307221
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:2293572
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:1624291
RGD:1600115
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:11059572
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:11341712
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 JBrowse link 1 143,171,457 143,278,485 RGD:1624291
RGD:1600115
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 JBrowse link 14 72,327,929 72,382,519 RGD:1624291
RGD:1600115
G Cyfip1 cytoplasmic FMR1 interacting protein 1 JBrowse link 1 114,258,773 114,347,138 RGD:11557987
G Dennd4c DENN domain containing 4C JBrowse link 5 105,100,081 105,195,634 RGD:1624291
RGD:1600115
G Dlc1 DLC1 Rho GTPase activating protein JBrowse link 16 58,776,489 59,247,752 RGD:2304073
G Dpep1 dipeptidase 1 JBrowse link 19 55,973,447 55,998,830 RGD:1624291
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:2302121
G Eef2k eukaryotic elongation factor-2 kinase JBrowse link 1 190,780,211 190,839,926 RGD:10401230
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:1601014
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:1624291
RGD:1600115
G Eprs glutamyl-prolyl-tRNA synthetase JBrowse link 13 103,300,911 103,371,651 RGD:1600115
RGD:1624291
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:2289971
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685544
G Fbp1 fructose-bisphosphatase 1 JBrowse link 17 396,175 417,480 RGD:1298915
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:1624291
RGD:1600115
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:1624291
RGD:1600115
G G6pc glucose-6-phosphatase, catalytic subunit JBrowse link 10 89,286,009 89,296,213 RGD:14695551
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:8554539
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:10402381
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 JBrowse link 4 118,852,046 118,901,583 RGD:1625427
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1624291
RGD:1600115
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:2307371
G Ghrhr growth hormone releasing hormone receptor JBrowse link 4 85,587,321 85,602,389 RGD:1624291
RGD:1600115
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1624291
RGD:1600115
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:1624291
RGD:1600115
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:2313661
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
RGD:1600115
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:11342811
G Gpt2 glutamic--pyruvic transaminase 2 JBrowse link 19 22,599,003 22,633,529 RGD:11342811
G Grb14 growth factor receptor bound protein 14 JBrowse link 3 50,937,403 51,054,447 RGD:12793049
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:2317845
G H2az1 H2A.Z variant histone 1 JBrowse link 2 243,105,224 243,107,333 RGD:9588479
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1626318
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:1599891
G Hnrnpk heterogeneous nuclear ribonucleoprotein K JBrowse link 17 6,664,730 6,676,753 RGD:10002778
RGD:10058978
RGD:10002795
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:2316798
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4889586
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:10046039
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10046039
RGD:1624291
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:1600115
RGD:1624291
G Inpp5k inositol polyphosphate-5-phosphatase K JBrowse link 10 63,775,639 63,796,879 RGD:1624291
RGD:1600115
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:2308854
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1624291
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:1624291
G Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:1624291
RGD:7257698
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
G Lpin1 lipin 1 JBrowse link 6 41,796,214 41,905,149 RGD:1641823
RGD:13792537
RGD:1624291
G Lpin2 lipin 2 JBrowse link 9 119,517,101 119,591,533 RGD:13792537
G Lpin3 lipin 3 JBrowse link 3 156,874,805 156,899,601 RGD:13792537
G Mars1 methionyl-tRNA synthetase 1 JBrowse link 7 70,585,011 70,602,425 RGD:1624291
RGD:1600115
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:2303745
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:10059628
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:13450916
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:9590198
G Otop1 otopetrin 1 JBrowse link 14 77,236,278 77,263,729 RGD:1600115
RGD:1624291
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:2299859
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:8552378
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:10428394
RGD:13792537
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:8553473
RGD:1624291
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:1624291
RGD:1600115
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:1624291
RGD:1600115
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:4108484
RGD:1624291
RGD:1600115
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 16 20,415,109 20,424,982 RGD:1624291
RGD:1600115
G Pklr pyruvate kinase L/R JBrowse link 2 188,449,158 188,458,034 RGD:1625596
RGD:13792537
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:13792537
G Pkm_v1 pyruvate kinase M1/2, variant 1 RGD:13792537
G Pkm_v2 pyruvate kinase M1/2, variant 2 RGD:13792537
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:8553780
RGD:1624291
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:14985223
G Pou4f2 POU class 4 homeobox 2 JBrowse link 19 33,160,180 33,163,821 RGD:1600115
RGD:1624291
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1624291
RGD:13792537
RGD:1600115
G Ppat phosphoribosyl pyrophosphate amidotransferase JBrowse link 14 33,580,541 33,614,919 RGD:2316798
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link 10 37,534,449 37,554,861 RGD:729591
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1642545
G Prkci protein kinase C, iota JBrowse link 2 115,941,998 116,002,550 RGD:2314946
RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1642671
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
RGD:1600115
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:12801493
G Rab10 RAB10, member RAS oncogene family JBrowse link 6 27,668,387 27,721,120 RGD:1600115
RGD:13792537
RGD:1624291
G Rab12 RAB12, member RAS oncogene family JBrowse link 9 114,683,985 114,709,613 RGD:13792537
G Rab13 RAB13, member RAS oncogene family JBrowse link 2 189,581,209 189,586,358 RGD:8554419
RGD:13792537
G Rab31 RAB31, member RAS oncogene family JBrowse link 9 113,370,072 113,504,606 RGD:1600115
RGD:1624291
G Rab8a RAB8A, member RAS oncogene family JBrowse link 16 19,355,047 19,376,776 RGD:8554419
RGD:13792537
G Rab8b RAB8B, member RAS oncogene family JBrowse link 8 72,641,680 72,714,646 RGD:13792537
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:10003129
G Rhoq ras homolog family member Q JBrowse link 6 10,533,151 10,568,582 RGD:1624291
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:1624291
RGD:13792537
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1643120
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547811
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:8553574
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:729591
G Slc22a12 solute carrier family 22 member 12 JBrowse link 1 221,910,787 221,919,277 RGD:13439745
G Slc25a33 solute carrier family 25 member 33 JBrowse link 5 166,701,463 166,726,794 RGD:1624291
RGD:1600115
G Slc29a2 solute carrier family 29 member 2 JBrowse link 1 220,306,622 220,314,631 RGD:2316934
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:7349316
RGD:13792537
RGD:1624291
RGD:1600115
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:7349316
G Sorbs1 sorbin and SH3 domain containing 1 JBrowse link 1 259,373,921 259,502,108 RGD:1624291
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:11059577
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:2325147
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:4891501
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:2308803
RGD:2308847
G Srebf1_v2 sterol regulatory element binding factor 1, variant 2 RGD:2308803
RGD:2308847
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:729792
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1600072
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:1600096
G Syap1 synapse associated protein 1 JBrowse link X 33,528,071 33,562,584 RGD:1600115
RGD:1624291
G Tbc1d4 TBC1 domain family, member 4 JBrowse link 15 85,927,978 86,105,829 RGD:7247577
RGD:1624291
G Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1 JBrowse link 10 63,471,330 63,491,713 RGD:1600115
RGD:1624291
G Trib3 tribbles pseudokinase 3 JBrowse link 3 147,814,056 147,819,650 RGD:1624291
RGD:1600115
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1624291
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1299378
G Uchl3 ubiquitin C-terminal hydrolase L3 JBrowse link 15 86,153,624 86,198,127 RGD:1624291
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:2313533
G Usf1 upstream transcription factor 1 JBrowse link 13 89,797,750 89,805,561 RGD:1624291
RGD:1600115
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
RGD:1600115
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:1625575
G Wdtc1 WD and tetratricopeptide repeats 1 JBrowse link 5 151,487,572 151,536,829 RGD:1624291
RGD:1600115
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma JBrowse link 12 23,789,547 23,817,884 RGD:7247577
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1624291
RGD:1600115
glucose import in response to insulin stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:1600115
RGD:14402447
RGD:729967
RGD:2303167
RGD:1624291
G Trarg1 trafficking regulator of GLUT4 (SLC2A4) 1 JBrowse link 10 63,471,330 63,491,713 RGD:1600115
RGD:1624291
insulin receptor recycling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:1624291
insulin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:8554450
RGD:1624291
RGD:1600115
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:1624291
RGD:1600115
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
RGD:1600115
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 JBrowse link 16 2,560,103 2,602,035 RGD:1624291
RGD:13792537
G Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link 19 43,932,543 43,967,452 RGD:8553632
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:1624291
RGD:13792537
RGD:1600115
RGD:10047313
G Csrp3 cysteine and glycine rich protein 3 JBrowse link 1 104,147,205 104,166,389 RGD:1624291
RGD:1600115
G Dnai1 dynein, axonemal, intermediate chain 1 JBrowse link 5 57,947,796 58,017,985 RGD:1624291
RGD:1600115
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:1624291
RGD:1600115
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 JBrowse link 20 31,055,292 31,072,469 RGD:1624291
RGD:1600115
G Foxc2 forkhead box C2 JBrowse link 19 53,044,379 53,047,081 RGD:1624291
RGD:1600115
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:1624291
RGD:13792537
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:13792537
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:1624291
RGD:13792537
G Foxo6 forkhead box O6 JBrowse link 5 139,208,153 139,227,288 RGD:13792537
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1600115
RGD:1624291
G Grb10 growth factor receptor bound protein 10 JBrowse link 14 92,021,851 92,122,249 RGD:8553640
RGD:13792537
G Grb14 growth factor receptor bound protein 14 JBrowse link 3 50,937,403 51,054,447 RGD:61620
RGD:13792537
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:1624291
RGD:1600115
G Grb7 growth factor receptor bound protein 7 JBrowse link 10 86,393,186 86,408,893 RGD:13792537
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
RGD:13792537
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:1624291
RGD:13792537
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:13210538
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:729306
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
RGD:1600115
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1580595
RGD:2306052
RGD:14700925
RGD:1624291
RGD:13210538
RGD:1600115
RGD:1299201
G Insrr insulin receptor-related receptor JBrowse link 2 187,161,817 187,181,400 RGD:1600115
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:8553954
RGD:13792537
RGD:1624291
RGD:1600115
G Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:1299201
RGD:13792537
RGD:1624291
G Irs3 insulin receptor substrate 3 JBrowse link 12 22,120,305 22,125,103 RGD:13792537
G Irs4 insulin receptor substrate 4 JBrowse link X 113,003,824 113,018,088 RGD:2301084
G Kl Klotho JBrowse link 12 942,974 987,206 RGD:1600115
G LOC259246 alpha-2u globulin PGCL1 RGD:1600115
G Nampt nicotinamide phosphoribosyltransferase JBrowse link 6 52,122,085 52,156,473 RGD:1624291
G Ndel1 nudE neurodevelopment protein 1-like 1 JBrowse link 10 55,398,919 55,456,654 RGD:1624291
RGD:1600115
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:625467
G Pdk2 pyruvate dehydrogenase kinase 2 JBrowse link 10 82,838,270 82,852,758 RGD:1600115
RGD:1624291
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:1600115
RGD:1624291
G Phip pleckstrin homology domain interacting protein JBrowse link 8 90,387,339 90,483,964 RGD:1624291
RGD:1600115
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1625251
RGD:13792537
RGD:1624291
RGD:1600115
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 16 20,415,109 20,424,982 RGD:1600115
RGD:13792537
RGD:1624291
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 5 135,069,972 135,145,633 RGD:1624291
RGD:13792537
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Ptpra protein tyrosine phosphatase, receptor type, A JBrowse link 3 122,976,066 123,084,585 RGD:1624291
RGD:1600115
G Rarres2 retinoic acid receptor responder 2 JBrowse link 4 78,205,809 78,208,956 RGD:1600115
RGD:1624291
G Rhoq ras homolog family member Q JBrowse link 6 10,533,151 10,568,582 RGD:1624291
RGD:1600115
G Rpe65 retinoid isomerohydrolase RPE65 JBrowse link 2 266,141,581 266,169,197 RGD:1624291
RGD:1600115
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1624291
RGD:1600115
G Shc1 SHC adaptor protein 1 JBrowse link 2 188,745,503 188,757,066 RGD:8553954
RGD:13792537
RGD:8553924
G Sik2 salt-inducible kinase 2 JBrowse link 8 55,309,005 55,408,608 RGD:1624291
G Slc2a8 solute carrier family 2 member 8 JBrowse link 3 12,020,227 12,029,920 RGD:1624291
RGD:1600115
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 JBrowse link 8 118,206,678 118,326,264 RGD:1624291
RGD:1600115
G Socs7 suppressor of cytokine signaling 7 JBrowse link 10 85,301,797 85,337,971 RGD:1624291
RGD:1600115
G Soga1 suppressor of glucose, autophagy associated 1 JBrowse link 3 153,130,268 153,188,909 RGD:1624291
RGD:13792537
G Sorbs1 sorbin and SH3 domain containing 1 JBrowse link 1 259,373,921 259,502,108 RGD:1624291
RGD:1600115
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291
RGD:1600115
G Stxbp4 syntaxin binding protein 4 JBrowse link 10 78,005,745 78,168,641 RGD:1624291
G Wdr6 WD repeat domain 6 JBrowse link 8 117,358,345 117,364,761 RGD:2301084
G Zfp106 zinc finger protein 106 JBrowse link 3 112,279,782 112,330,288 RGD:1624291
RGD:13792537
insulin receptor signaling pathway via phosphatidylinositol 3-kinase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2cd5 C2 calcium-dependent domain containing 5 JBrowse link 4 177,245,868 177,331,910 RGD:1624291
RGD:1600115
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:1600115
RGD:1624291
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1624291
RGD:1600115
negative regulation of cellular response to insulin stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 JBrowse link 7 26,256,179 26,306,128 RGD:1600115
RGD:1624291
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13792716
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:13794384
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1624291
negative regulation of insulin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:632173
G Ankrd26 ankyrin repeat domain 26 JBrowse link 4 150,548,656 150,616,928 RGD:1624291
G Enho energy homeostasis associated JBrowse link 5 58,018,039 58,019,836 RGD:1624291
RGD:1600115
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:1624291
RGD:1600115
G Gpr21 G protein-coupled receptor 21 JBrowse link 3 21,764,377 21,767,300 RGD:1624291
RGD:1600115
G Grb10 growth factor receptor bound protein 10 JBrowse link 14 92,021,851 92,122,249 RGD:1624291
RGD:13792537
RGD:1600115
G Grb14 growth factor receptor bound protein 14 JBrowse link 3 50,937,403 51,054,447 RGD:61620
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2307023
G Grb7 growth factor receptor bound protein 7 JBrowse link 10 86,393,186 86,408,893 RGD:13792537
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
RGD:1600115
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Inpp5f inositol polyphosphate-5-phosphatase F JBrowse link 1 200,037,749 200,116,524 RGD:11059577
G Inpp5k inositol polyphosphate-5-phosphatase K JBrowse link 10 63,775,639 63,796,879 RGD:1624291
RGD:13792537
G Inppl1 inositol polyphosphate phosphatase-like 1 JBrowse link 1 166,898,177 166,912,524 RGD:2312443
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:8554248
G Kank1 KN motif and ankyrin repeat domains 1 JBrowse link 1 243,201,073 243,398,531 RGD:1624291
RGD:1600115
G Lmbrd1 LMBR1 domain containing 1 JBrowse link 9 30,939,555 31,038,381 RGD:1624291
G Mir143 microRNA 143 JBrowse link 18 56,971,273 56,971,377 RGD:1624291
G Mstn myostatin JBrowse link 9 53,310,977 53,315,804 RGD:1624291
RGD:1600115
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
RGD:1600115
G Ncoa5 nuclear receptor coactivator 5 JBrowse link 3 161,465,733 161,498,951 RGD:1624291
RGD:1600115
G Nucb2 nucleobindin 2 JBrowse link 1 185,106,773 185,143,278 RGD:9831186
G Pid1 phosphotyrosine interaction domain containing 1 JBrowse link 9 91,667,748 91,683,468 RGD:1624291
RGD:1600115
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:6484547
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1624291
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:8553365
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1600115
RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1600115
RGD:1624291
G Ptpre protein tyrosine phosphatase, receptor type, E JBrowse link 1 207,820,719 207,987,123 RGD:8553759
RGD:1624291
G Ptprf protein tyrosine phosphatase, receptor type, F JBrowse link 5 137,036,936 137,112,930 RGD:1642757
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298860
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:8554230
RGD:1624291
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1624291
RGD:1600115
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:1624291
RGD:1600115
G Trim72 tripartite motif containing 72 JBrowse link 1 199,450,042 199,457,902 RGD:1624291
RGD:1600115
G Tsc1 TSC complex subunit 1 JBrowse link 3 7,219,955 7,269,063 RGD:13792537
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:13792537
G Tsc2_v1 TSC complex subunit 2, variant 1 RGD:13792537
G Tsc2_v2 TSC complex subunit 2, variant 2 RGD:13792537
G Ybx1 Y box binding protein 1 JBrowse link 5 138,319,754 138,336,721 RGD:727501
positive regulation of cellular response to insulin stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1qtnf9 C1q and TNF related 9 JBrowse link 15 41,069,579 41,080,961 RGD:1624291
RGD:1600115
G Esrra estrogen related receptor, alpha JBrowse link 1 222,168,729 222,178,842 RGD:10401858
G Myo1c myosin 1C JBrowse link 10 63,803,311 63,819,614 RGD:11073622
RGD:1624291
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:11532776
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:13208948
positive regulation of insulin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipor1 adiponectin receptor 1 JBrowse link 13 51,240,470 51,260,233 RGD:2317907
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:11039409
G C1qtnf12 C1q and TNF related 12 JBrowse link 5 173,390,901 173,395,276 RGD:1624291
RGD:13792537
G Erfe erythroferrone JBrowse link 9 98,505,136 98,513,005 RGD:13792537
G Gkap1 G kinase anchoring protein 1 JBrowse link 17 6,785,428 6,825,145 RGD:1600115
RGD:1624291
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13508599
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1624291
RGD:1600115
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:8553881
RGD:1624291
RGD:1600115
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:5128575
G Marcks myristoylated alanine rich protein kinase C substrate JBrowse link 20 42,966,140 42,971,838 RGD:9685323
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:13204821
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1600115
RGD:1624291
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 JBrowse link 13 48,679,726 48,709,663 RGD:1624291
RGD:1600115
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:13208948
G Osbpl8 oxysterol binding protein-like 8 JBrowse link 7 53,878,906 54,030,110 RGD:1600115
RGD:1624291
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:11533947
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:8553908
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:1600115
RGD:1624291
G Serpina12 serpin family A member 12 JBrowse link 6 127,696,501 127,711,238 RGD:1624291
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Sorbs1 sorbin and SH3 domain containing 1 JBrowse link 1 259,373,921 259,502,108 RGD:1600115
RGD:1624291
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1581139
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1600115
RGD:1624291
regulation of cellular response to insulin stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 JBrowse link 7 41,114,606 41,223,138 RGD:1600115
RGD:1624291
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:1600115
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1600115
RGD:1624291
G Uso1 USO1 vesicle transport factor JBrowse link 14 17,371,451 17,436,948 RGD:1600115
RGD:1624291
regulation of insulin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baiap2l1 BAI1-associated protein 2-like 1 JBrowse link 12 12,226,967 12,321,172 RGD:1600115
G Ccnd3 cyclin D3 JBrowse link 9 15,404,816 15,410,905 RGD:1624291
RGD:1600115
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:1624291
RGD:1600115
G Ffar3 free fatty acid receptor 3 JBrowse link 1 89,302,035 89,304,064 RGD:1600115
RGD:1624291
G Mir494 microRNA 494 JBrowse link 6 133,864,370 133,864,452 RGD:1624291
G Mzb1 marginal zone B and B1 cell-specific protein JBrowse link 18 28,436,546 28,438,607 RGD:1600115
RGD:1624291
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 JBrowse link 13 48,679,726 48,709,663 RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1624291
RGD:1600115
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1625241
G Rarres2 retinoic acid receptor responder 2 JBrowse link 4 78,205,809 78,208,956 RGD:1624291
G Rbm4 RNA binding motif protein 4 JBrowse link 1 220,038,403 220,049,756 RGD:1624291
G Sesn3 sestrin 3 JBrowse link 8 12,823,060 12,878,749 RGD:1624291
RGD:1600115
G Sik2 salt-inducible kinase 2 JBrowse link 8 55,309,005 55,408,608 RGD:1624291
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1624291
G Vwa2 von Willebrand factor A domain containing 2 JBrowse link 1 277,689,478 277,730,407 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    response to stimulus 9928
      response to endogenous stimulus 2083
        response to hormone 1326
          response to peptide hormone 575
            cellular response to peptide hormone stimulus 371
              cellular response to insulin stimulus 252
                glucose import in response to insulin stimulus 2
                insulin receptor signaling pathway + 128
                negative regulation of cellular response to insulin stimulus + 45
                positive regulation of cellular response to insulin stimulus + 29
                regulation of cellular response to insulin stimulus + 90
Path 2
Term Annotations click to browse term
  biological_process 18166
    cellular process 16266
      cellular response to stimulus 8400
        cellular response to chemical stimulus 3387
          cellular response to nitrogen compound 901
            cellular response to organonitrogen compound 832
              cellular response to peptide 446
                cellular response to peptide hormone stimulus 371
                  cellular response to insulin stimulus 252
                    glucose import in response to insulin stimulus 2
                    insulin receptor signaling pathway + 128
                    negative regulation of cellular response to insulin stimulus + 45
                    positive regulation of cellular response to insulin stimulus + 29
                    regulation of cellular response to insulin stimulus + 90
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.