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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta1 production
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Accession:GO:0032905 term browser browse the term
Definition:The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: TGF-B1 production;   TGFB1 production


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negative regulation of transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1a FKBP prolyl isomerase 1A ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
negative regulation of transforming growth factor beta1 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd2ap CD2-associated protein ISO MGI:MGI:98725 (MGI:MGI:5297732|PMID:21911934) RGD PMID:21911934 MGI:MGI:5297732 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) ISO
IEA
(PMID:15899807)
GO_REF:0000107
RGD
Ensembl
PMID:15899807 GO_REF:0000107 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Gata6 GATA binding protein 6 IEA
ISO
GO_REF:0000107
(PMID:21127043)
Ensembl
RGD
PMID:21127043 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta ISO
ISS
(PMID:26126825)
GO_REF:0000024
RGD
UniProt
PMID:26126825 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp ISO
IBA
(MGI:MGI:5638298|PMID:25690660)
PMID:21873635
RGD PMID:25690660, PMID:21873635 MGI:MGI:5638298, RGD:13792537 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link
positive regulation of transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:7737999)
UniProt
Ensembl
RGD
PMID:7737999 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
positive regulation of transforming growth factor beta1 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 ISO (PMID:16374430) RGD PMID:16374430 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO
IEA
MGI:MGI:3608773 (MGI:MGI:3772530|PMID:18097059)
GO_REF:0000107
RGD
Ensembl
PMID:18097059 GO_REF:0000107, MGI:MGI:3772530 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Foxp3 forkhead box P3 ISO (MGI:MGI:3697020|PMID:17028180) RGD PMID:17028180 MGI:MGI:3697020 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Lum lumican ISO (MGI:MGI:5295830|PMID:21931815) RGD PMID:21931815 MGI:MGI:5295830 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Serpinb7 serpin family B member 7 IMP RGD PMID:21945418 RGD:7207383 NCBI chr13:27,282,456...27,354,775
Ensembl chr13:27,312,498...27,354,052
JBrowse link
transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrros negative regulator of reactive oxygen species ISS
ISO
GO_REF:0000024
(MGI:MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024, MGI:MGI:6192878 NCBI chr11:71,872,728...71,889,897
Ensembl chr11:71,872,830...71,889,887
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      cytokine production 838
        transforming growth factor beta production 44
          transforming growth factor beta1 production 12
            negative regulation of transforming growth factor beta1 production + 6
            positive regulation of transforming growth factor beta1 production + 6
            regulation of transforming growth factor beta1 production + 11
            transforming growth factor beta1 activation + 3
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            cytokine production 838
              transforming growth factor beta production 44
                transforming growth factor beta1 production 12
                  negative regulation of transforming growth factor beta1 production + 6
                  positive regulation of transforming growth factor beta1 production + 6
                  regulation of transforming growth factor beta1 production + 11
                  transforming growth factor beta1 activation + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.