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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta3 production
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Accession:GO:0032907 term browser browse the term
Definition:The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: TGF-B3 production;   TGFB3 production


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negative regulation of transforming growth factor beta3 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule ISO
ISS
(PMID:16930538)
GO_REF:0000024
RGD
UniProt
PMID:16930538, PMID:16930538 GO_REF:0000024, RGD:8553566 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
positive regulation of transforming growth factor beta3 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16891311, PMID:21308733 RGD:1625706, RGD:10059386 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Smad3 SMAD family member 3 IMP RGD PMID:16891311 RGD:1625706 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
regulation of transforming growth factor beta3 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrc32 leucine rich repeat containing 32 ISO (MGI:MGI:5920420|PMID:28912269) RGD PMID:28912269 MGI:MGI:5920420 NCBI chr 1:163,443,972...163,457,426
Ensembl chr 1:163,445,527...163,457,424
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      cytokine production 838
        transforming growth factor beta production 44
          transforming growth factor beta3 production 4
            negative regulation of transforming growth factor beta3 production + 1
            positive regulation of transforming growth factor beta3 production + 2
            regulation of transforming growth factor beta3 production + 4
            transforming growth factor beta3 activation + 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            cytokine production 838
              transforming growth factor beta production 44
                transforming growth factor beta3 production 4
                  negative regulation of transforming growth factor beta3 production + 1
                  positive regulation of transforming growth factor beta3 production + 2
                  regulation of transforming growth factor beta3 production + 4
                  transforming growth factor beta3 activation + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.