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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of activin receptor signaling pathway
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Accession:GO:0032926 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
Synonyms:exact_synonym: down regulation of activin receptor signaling pathway;   downregulation of activin receptor signaling pathway;   negative regulation of activin receptor signalling pathway
 narrow_synonym: inhibition of activin receptor signaling pathway
 related_synonym: negative regulation of activin signaling pathway;   negative regulation of activin signalling pathway


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negative regulation of activin receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 ISO
IEA
(PMID:9884026)
GO_REF:0000107
RGD
Ensembl
PMID:9884026 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist ISO (PMID:9660951)
(MGI:1858315|PMID:10748465)
RGD PMID:9660951, PMID:10748465 MGI:1858315 NCBI chr 5:101,003,019...101,006,375
Ensembl chr 5:101,003,023...101,006,375
JBrowse link
G Fst follistatin ISO
IBA
(PMID:11948405), (PMID:12697670), (PMID:12702211)
PMID:21873635
RGD PMID:11948405, PMID:12697670, PMID:12702211, PMID:21873635 RGD:13792537 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Fstl3 follistatin like 3 ISO
IBA
(PMID:11948405), (PMID:12697670)
PMID:21873635
RGD PMID:11948405, PMID:12697670, PMID:21873635 RGD:13792537 NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
JBrowse link
G Igsf1 immunoglobulin superfamily, member 1 ISO (PMID:11266516) RGD PMID:11266516 NCBI chr  X:136,792,637...136,808,107
Ensembl chr  X:136,792,643...136,807,885
JBrowse link
G Lemd3 LEM domain containing 3 ISO (PMID:15647271) RGD PMID:15647271 NCBI chr 7:62,976,671...63,045,860
Ensembl chr 7:62,996,336...63,045,728
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:1353670|PMID:10681527)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:10681527 GO_REF:0000024, GO_REF:0000107, MGI:1353670 NCBI chr 4:10,995,241...12,472,423
Ensembl chr 4:10,995,234...11,610,518
JBrowse link
G Mir210 microRNA 210 ISO (MGI:3851892|PMID:19520079) RGD PMID:19520079 MGI:3851892 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Ski SKI proto-oncogene ISO (PMID:14699069) RGD PMID:14699069 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Synj2bp synaptojanin 2 binding protein ISO (MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:3623710 NCBI chr 6:105,224,166...105,261,549
Ensembl chr 6:105,224,166...105,261,549
JBrowse link
negative regulation of nodal signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dact2 dishevelled-binding antagonist of beta-catenin 2 IBA
ISO
PMID:21873635
(MGI:3809364|PMID:18716284), (MGI:5437437|PMID:17197390)
RGD PMID:17197390, PMID:18716284, PMID:21873635 MGI:3809364, MGI:5437437, RGD:13792537 NCBI chr 1:56,159,435...56,169,443
Ensembl chr 1:56,159,426...56,168,351
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
G Lefty1 left right determination factor 1 ISO (MGI:3042530|PMID:15062104) RGD PMID:15062104 MGI:3042530 NCBI chr13:99,212,778...99,217,786
Ensembl chr13:99,214,389...99,217,786
JBrowse link
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:101,003,019...101,006,375
Ensembl chr 5:101,003,023...101,006,375
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain BMP antagonist family member 5 ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    negative regulation of biological process 5689
      negative regulation of signaling 1374
        negative regulation of signal transduction 1236
          negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 129
            negative regulation of activin receptor signaling pathway 13
              negative regulation of nodal signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          signal transduction 7010
            cell surface receptor signaling pathway 2761
              enzyme linked receptor protein signaling pathway 969
                transmembrane receptor protein serine/threonine kinase signaling pathway 387
                  regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 257
                    negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 129
                      negative regulation of activin receptor signaling pathway 13
                        negative regulation of nodal signaling pathway + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.