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ONTOLOGY REPORT - ANNOTATIONS


Term:collagen metabolic process
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Accession:GO:0032963 term browser browse the term
Definition:The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
Synonyms:exact_synonym: collagen metabolism


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collagen metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a2 collagen type I alpha 2 chain JBrowse link 4 31,534,225 31,569,152 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Id1 inhibitor of DNA binding 1, HLH protein JBrowse link 3 148,214,623 148,216,715 RGD:1624291
RGD:1600115
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G P3h1 prolyl 3-hydroxylase 1 JBrowse link 5 138,279,597 138,294,280 RGD:13792537
RGD:1600115
G P3h2 prolyl 3-hydroxylase 2 JBrowse link 11 78,028,885 78,169,746 RGD:8553392
RGD:13792537
RGD:1600115
RGD:1624291
G P3h3 prolyl 3-hydroxylase 3 JBrowse link 4 157,359,331 157,375,186 RGD:13792537
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 JBrowse link 5 164,720,629 164,747,071 RGD:13792537
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 JBrowse link 8 99,977,334 100,059,736 RGD:13792537
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 JBrowse link 12 22,716,421 22,726,982 RGD:1624291
RGD:13792537
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1642520
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:1600115
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
G Tns2 tensin 2 JBrowse link 7 143,702,623 143,720,995 RGD:1624291
RGD:1600115
G Tnxb tenascin XB RGD:1624291
G Vipas39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog JBrowse link 6 111,271,283 111,296,013 RGD:1624291
RGD:1600115
G Vps33b VPS33B, late endosome and lysosome associated JBrowse link 1 142,060,955 142,083,955 RGD:1624291
RGD:1600115
collagen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 JBrowse link 14 19,866,278 20,072,896 RGD:1624291
RGD:1600115
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4143276
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:1624291
RGD:1600115
G Col5a1 collagen type V alpha 1 chain JBrowse link 3 6,430,180 6,581,010 RGD:1600115
RGD:1624291
G P3h3 prolyl 3-hydroxylase 3 JBrowse link 4 157,359,331 157,375,186 RGD:1624291
G P3h4 prolyl 3-hydroxylase family member 4 (non-enzymatic) JBrowse link 10 88,318,231 88,325,326 RGD:1624291
RGD:1600115
G Rcn3 reticulocalbin 3 JBrowse link 1 101,076,971 101,086,198 RGD:1600115
RGD:1624291
G Serpinh1 serpin family H member 1 JBrowse link 1 164,301,010 164,308,306 RGD:1624291
RGD:1600115
G Tram2 translocation associated membrane protein 2 JBrowse link 9 27,117,861 27,192,166 RGD:1624291
RGD:1600115
collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam15 ADAM metallopeptidase domain 15 JBrowse link 2 188,661,831 188,672,337 RGD:1600115
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:1624291
RGD:1600115
G Ctsk cathepsin K JBrowse link 2 196,655,469 196,666,447 RGD:1600115
RGD:1624291
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:1624291
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:1624291
RGD:1600115
G LOC103694864 matrix metalloproteinase-28-like RGD:13792537
G LOC103694874 stromelysin-3 RGD:13792537
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:1600115
RGD:13792537
G Mmp10 matrix metallopeptidase 10 JBrowse link 8 5,734,348 5,742,243 RGD:13792537
G Mmp11 matrix metallopeptidase 11 JBrowse link 20 13,670,051 13,678,834 RGD:1624291
RGD:13792537
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:13792537
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:1600115
RGD:13792537
RGD:1624291
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1624291
RGD:13792537
G Mmp15 matrix metallopeptidase 15 JBrowse link 19 10,079,881 10,101,380 RGD:13792537
G Mmp16 matrix metallopeptidase 16 JBrowse link 5 31,568,344 31,818,368 RGD:1624291
RGD:13792537
RGD:1600115
G Mmp17 matrix metallopeptidase 17 JBrowse link 12
12
30,353,874
30,701,900
30,356,526
30,728,683
RGD:13792537
G Mmp19 matrix metallopeptidase 19 JBrowse link 7 3,216,392 3,224,202 RGD:13792537
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) JBrowse link 8 5,622,657 5,688,762 RGD:13792537
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1624291
RGD:13792537
RGD:1600115
RGD:7207278
G Mmp20 matrix metallopeptidase 20 JBrowse link 8 5,823,147 5,875,555 RGD:13792537
G Mmp21 matrix metallopeptidase 21 JBrowse link 1 205,745,119 205,750,786 RGD:13792537
G Mmp23 matrix metallopeptidase 23 JBrowse link 5 173,078,811 173,082,834 RGD:13792537
G Mmp24 matrix metallopeptidase 24 JBrowse link 3 151,307,309 151,355,401 RGD:13792537
G Mmp27 matrix metallopeptidase 27 JBrowse link 8 5,790,019 5,799,938 RGD:13792537
G Mmp28 matrix metallopeptidase 28 JBrowse link 10 70,660,691 70,681,672 RGD:13792537
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:13792537
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:13792537
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:13792537
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:7207278
RGD:13792537
RGD:1600115
RGD:1624291
G Mrc2 mannose receptor, C type 2 JBrowse link 10 93,520,272 93,581,599 RGD:1600115
RGD:1624291
G Pepd peptidase D JBrowse link 1 90,820,670 91,285,128 RGD:1600115
G Prss2 protease, serine, 2 JBrowse link 4 70,689,737 70,694,816 RGD:1600115
negative regulation of collagen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:2316149
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7245949
G Cygb cytoglobin JBrowse link 10 105,618,325 105,628,091 RGD:9685174
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:12904676
G Emilin1 elastin microfibril interfacer 1 JBrowse link 6 26,821,249 26,829,013 RGD:1600115
RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685562
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:13504840
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1624291
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1580115
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:2324888
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:8553021
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:9850086
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:9850086
negative regulation of collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cst3 cystatin C JBrowse link 3 143,219,671 143,223,544 RGD:1624291
positive regulation of collagen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:13506828
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Cbx8 chromobox 8 JBrowse link 10 108,148,073 108,150,511 RGD:9586727
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549527
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:2314490
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:7257540
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:2312266
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:1624291
RGD:1600115
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
RGD:1600115
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889158
G Itga2 integrin subunit alpha 2 JBrowse link 2 46,996,904 47,097,011 RGD:2307406
G Larp6 La ribonucleoprotein domain family, member 6 JBrowse link 8 65,611,570 65,632,706 RGD:1624291
RGD:1600115
G Ltbp1 latent transforming growth factor beta binding protein 1 JBrowse link 6 21,203,502 21,600,441 RGD:10412058
G Mkx mohawk homeobox JBrowse link 17 60,537,615 60,553,284 RGD:1624291
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532676
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:10449487
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2292205
G Prdx5 peroxiredoxin 5 JBrowse link 1 222,164,462 222,167,447 RGD:1624291
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:1624291
RGD:1600115
G Scx scleraxis bHLH transcription factor JBrowse link 7 117,519,075 117,521,093 RGD:1624291
RGD:1600115
G Serpinb7 serpin family B member 7 JBrowse link 13 27,282,456 27,354,775 RGD:7207383
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:13208547
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:1624291
RGD:1600115
G Suco SUN domain containing ossification factor JBrowse link 13 79,736,485 79,801,133 RGD:1600115
RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
RGD:11073665
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
RGD:1600115
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:1642796
G Uts2 urotensin 2 JBrowse link 5 168,078,748 168,084,133 RGD:2306814
RGD:2306811
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:1600115
RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115
positive regulation of collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Idua iduronidase, alpha-L- JBrowse link 14 2,041,828 2,056,762 RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
positive regulation of collagen metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:7207234
regulation of collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fap fibroblast activation protein, alpha JBrowse link 3 48,467,781 48,536,242 RGD:1624291
RGD:1600115
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:1600115
RGD:1624291
regulation of collagen metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Mfap4 microfibril associated protein 4 JBrowse link 10 47,765,463 47,768,484 RGD:1624291

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  biological_process 17883
    metabolic process 10636
      collagen metabolic process 111
        collagen biosynthetic process + 55
        collagen catabolic process + 37
        negative regulation of collagen metabolic process + 15
        positive regulation of collagen metabolic process + 35
        regulation of collagen metabolic process + 54
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