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ONTOLOGY REPORT - ANNOTATIONS


Term:collagen biosynthetic process
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Accession:GO:0032964 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
Synonyms:exact_synonym: collagen anabolism;   collagen biosynthesis;   collagen formation;   collagen synthesis


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collagen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 JBrowse link 14 19,866,278 20,072,896 RGD:1624291
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4143276
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:1624291
G Col5a1 collagen type V alpha 1 chain JBrowse link 3 6,430,180 6,581,010 RGD:1600115
RGD:1624291
G P3h3 prolyl 3-hydroxylase 3 JBrowse link 4 157,359,331 157,375,186 RGD:1624291
G P3h4 prolyl 3-hydroxylase family member 4 (non-enzymatic) JBrowse link 10 88,318,231 88,325,326 RGD:1624291
RGD:1600115
G Rcn3 reticulocalbin 3 JBrowse link 1 101,076,971 101,086,198 RGD:1600115
RGD:1624291
G Serpinh1 serpin family H member 1 JBrowse link 1 164,301,010 164,308,306 RGD:1624291
RGD:1600115
G Tram2 translocation associated membrane protein 2 JBrowse link 9 27,117,861 27,192,166 RGD:1624291
negative regulation of collagen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:2316149
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7245949
G Cygb cytoglobin JBrowse link 10 105,618,325 105,628,091 RGD:9685174
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:12904676
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:15045602
G Emilin1 elastin microfibril interfacer 1 JBrowse link 6 26,821,249 26,829,013 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685562
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:1625201
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:13504840
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1624291
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1580115
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1625201
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:2324888
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:8553021
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:9850086
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:9850086
positive regulation of collagen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:13506828
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Cbx8 chromobox 8 JBrowse link 10 108,148,073 108,150,511 RGD:9586727
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549527
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:2314490
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:7257540
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:2312266
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:1624291
RGD:1600115
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889158
G Itga2 integrin subunit alpha 2 JBrowse link 2 46,996,904 47,097,011 RGD:2307406
G Larp6 La ribonucleoprotein 6, translational regulator JBrowse link 8 65,611,570 65,632,706 RGD:1624291
G Ltbp1 latent transforming growth factor beta binding protein 1 JBrowse link 6 21,203,502 21,600,441 RGD:10412058
G Mkx mohawk homeobox JBrowse link 17 60,537,615 60,553,284 RGD:1624291
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532676
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:10449487
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2292205
G Prdx5 peroxiredoxin 5 JBrowse link 1 222,164,462 222,167,447 RGD:1624291
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:1624291
G Scx scleraxis bHLH transcription factor JBrowse link 7 117,519,075 117,521,093 RGD:1624291
G Serpinb7 serpin family B member 7 JBrowse link 13 27,282,456 27,354,775 RGD:7207383
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:13208547
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:1624291
G Suco SUN domain containing ossification factor JBrowse link 13 79,736,485 79,801,133 RGD:1600115
RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
RGD:11073665
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
RGD:1600115
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:1642796
G Uts2 urotensin 2 JBrowse link 5 168,078,748 168,084,133 RGD:2306814
RGD:2306811
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:1600115
RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115

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Term Annotations click to browse term
  biological_process 19676
    metabolic process 11952
      collagen metabolic process 113
        collagen biosynthetic process 58
          negative regulation of collagen biosynthetic process 17
          positive regulation of collagen biosynthetic process 32
          regulation of collagen biosynthetic process + 49
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.