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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of T cell differentiation in thymus
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Accession:GO:0033085 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: negative regulation of thymic T cell differentiation;   negative regulation of thymocyte cell differentiation;   negative regulation of thymocyte differentiation
 related_synonym: negative regulation of T cell development in thymus


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negative regulation of T cell differentiation in thymus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
G Nfkbid NFKB inhibitor delta JBrowse link 1 88,883,816 88,892,543 RGD:1624291
G Zc3h8 zinc finger CCCH type containing 8 JBrowse link 3 121,471,836 121,488,528 RGD:1624291
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1624291
RGD:1600115
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
G Tmem131l transmembrane 131 like JBrowse link 2 182,897,332 183,031,273 RGD:1624291
negative regulation of positive thymic T cell selection term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    immune system process 2693
      leukocyte activation 1009
        lymphocyte activation 829
          lymphocyte differentiation 392
            T cell differentiation 279
              T cell differentiation in thymus 93
                negative regulation of T cell differentiation in thymus 9
                  negative regulation of immature T cell proliferation in thymus 5
                  negative regulation of positive thymic T cell selection 1
Path 2
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure development 6155
        multicellular organism development 5623
          system development 5157
            immune system development 1046
              hematopoietic or lymphoid organ development 982
                hemopoiesis 930
                  leukocyte differentiation 575
                    lymphocyte differentiation 392
                      T cell differentiation 279
                        T cell differentiation in thymus 93
                          regulation of T cell differentiation in thymus 30
                            negative regulation of T cell differentiation in thymus 9
                              negative regulation of immature T cell proliferation in thymus 5
                              negative regulation of positive thymic T cell selection 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.