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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell receptor V(D)J recombination
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Accession:GO:0033153 term browser browse the term
Definition:The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
Synonyms:exact_synonym: TCR V(D)J recombination
 narrow_synonym: T cell receptor V-D-J joining;   T cell receptor V-J joining;   T cell receptor V-J recombination


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T cell receptor V(D)J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:1624291
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:1600115
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Tcf7 transcription factor 7 JBrowse link 10 37,616,033 37,646,027 RGD:1624291
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1600115

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  biological_process 19576
    immune system process 2692
      somatic diversification of immune receptors 81
        somatic diversification of immune receptors via germline recombination within a single locus 74
          V(D)J recombination 19
            T cell receptor V(D)J recombination 6
Path 2
Term Annotations click to browse term
  biological_process 19576
    developmental process 6694
      anatomical structure development 6153
        multicellular organism development 5621
          system development 5156
            animal organ development 3939
              hematopoietic or lymphoid organ development 982
                hemopoiesis 930
                  leukocyte differentiation 575
                    lymphocyte differentiation 392
                      T cell differentiation 279
                        somatic diversification of T cell receptor genes 6
                          somatic recombination of T cell receptor gene segments 6
                            T cell receptor V(D)J recombination 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.