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ONTOLOGY REPORT - ANNOTATIONS


Term:calmodulin-dependent protein phosphatase activity
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Accession:GO:0033192 term browser browse the term
Definition:Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.
Synonyms:exact_synonym: calcium- and calmodulin-dependent protein phosphatase activity;   calcium/calmodulin-dependent protein phosphatase activity
 narrow_synonym: calcineurin activity
 related_synonym: Ca2+/CaM-dependent protein phosphatase activity
 xref: reactome:R-HSA-2730849 "Calcineurin binds and dephosphorylates NFAT";   reactome:R-HSA-4551451 "Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling"


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calmodulin-dependent protein phosphatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A JBrowse link 6 94,433,658 94,484,979 RGD:1600115
RGD:1624291
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F JBrowse link 11 88,313,709 88,343,726 RGD:1600115
RGD:1624291
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:1600115
RGD:13792537
RGD:1624291
RGD:13507300
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1600115
RGD:13792537
RGD:1624291
G Ppp3cc protein phosphatase 3 catalytic subunit gamma JBrowse link 15 51,896,427 51,968,075 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19528
    catalytic activity 6039
      catalytic activity, acting on a protein 2282
        phosphoprotein phosphatase activity 172
          protein serine/threonine phosphatase activity 59
            calcium-dependent protein serine/threonine phosphatase activity 6
              calmodulin-dependent protein phosphatase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 19528
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 781
          phosphoric ester hydrolase activity 369
            phosphatase activity 274
              phosphoprotein phosphatase activity 172
                protein serine/threonine phosphatase activity 59
                  calcium-dependent protein serine/threonine phosphatase activity 6
                    calmodulin-dependent protein phosphatase activity 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.