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ONTOLOGY REPORT - ANNOTATIONS


Term:CORVET complex
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Accession:GO:0033263 term browser browse the term
Definition:A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.


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CORVET complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfbrap1 transforming growth factor, beta receptor associated protein 1 JBrowse link 9 49,852,560 49,902,943 RGD:1624291
G Vps11 VPS11 core subunit of CORVET and HOPS complexes JBrowse link 8 48,677,492 48,692,295 RGD:1624291
G Vps16 VPS16 core subunit of CORVET and HOPS complexes JBrowse link 3 122,947,887 122,969,543 RGD:1624291
G Vps18 VPS18 core subunit of CORVET and HOPS complexes JBrowse link 3 111,097,352 111,108,206 RGD:1624291
G Vps33a VPS33A core subunit of CORVET and HOPS complexes JBrowse link 12 38,459,816 38,482,903 RGD:1600115
RGD:13792537
RGD:1624291
G Vps33b VPS33B, late endosome and lysosome associated JBrowse link 1 142,060,955 142,083,955 RGD:13792537
G Vps8 VPS8 subunit of CORVET complex JBrowse link 11 83,104,912 83,323,606 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19951
    protein-containing complex 5828
      vesicle tethering complex 75
        CORVET complex 7
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        membrane-bounded organelle 10978
          vesicle 1996
            intracellular vesicle 1839
              cytoplasmic vesicle 1834
                endosome 835
                  CORVET complex 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.