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ONTOLOGY REPORT - ANNOTATIONS


Term:Leydig cell differentiation
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Accession:GO:0033327 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.


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Leydig cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2289137
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:4781870
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:4781870
G Dhh desert hedgehog signaling molecule JBrowse link 7 140,575,288 140,580,783 RGD:1624291
RGD:1600115
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 21,696,796 21,699,241 RGD:2302236
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 JBrowse link 17 1,579,319 1,610,745 RGD:4781870
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4781870
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:4781870
G Map7 microtubule-associated protein 7 JBrowse link 1 15,620,665 15,748,203 RGD:1624291
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:2302287
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 54,734,385 54,738,513 RGD:1624291
RGD:1600115
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:1624291
RGD:1600115
G Plekha1 pleckstrin homology domain containing A1 JBrowse link 1 201,429,716 201,481,411 RGD:1624291
RGD:1600115
G Sf1 splicing factor 1 JBrowse link 1 221,735,512 221,749,216 RGD:1624291
RGD:1600115
G Sgpl1 sphingosine-1-phosphate lyase 1 JBrowse link 20 30,699,936 30,769,178 RGD:1624291
RGD:1600115
G Tmf1 TATA element modulatory factor 1 JBrowse link 4 129,521,986 129,546,024 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    developmental process 6505
      developmental process involved in reproduction 1117
        Leydig cell differentiation 18
Path 2
Term Annotations click to browse term
  biological_process 18008
    developmental process 6505
      anatomical structure development 5993
        multicellular organism development 5478
          system development 5028
            reproductive system development 572
              reproductive structure development 567
                gonad development 313
                  male gonad development 192
                    Leydig cell differentiation 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.