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ONTOLOGY REPORT - ANNOTATIONS


Term:Slx1-Slx4 complex
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Accession:GO:0033557 term browser browse the term
Definition:A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.


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Slx1-Slx4 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
RGD:13792537
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
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  cellular_component 19843
    protein-containing complex 5779
      Slx1-Slx4 complex 2
Path 2
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  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        intracellular organelle 12030
          intracellular membrane-bounded organelle 9976
            nucleus 6783
              nuclear lumen 3992
                nuclear chromosome 656
                  Slx1-Slx4 complex 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.