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Term:Elongator holoenzyme complex
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Accession:GO:0033588 term browser browse the term
Definition:A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes.
Comment:Despite its name, this complex is no longer thought to be directly involved in transcriptional elongation (PMID:23165209).
Synonyms:related_synonym: Elongator core complex
 alt_id: GO:0033589

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Elongator holoenzyme complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07053185.1 RGD:13792537
G Elp1 elongator complex protein 1 JBrowse link 5 73,503,406 73,552,798 RGD:1600115
G Elp2 elongator acetyltransferase complex subunit 2 JBrowse link 18 16,544,515 16,581,086 RGD:1624291
G Elp3 elongator acetyltransferase complex subunit 3 JBrowse link 15 48,942,866 49,005,074 RGD:1624291
G Elp4 elongator acetyltransferase complex subunit 4 JBrowse link 3 95,733,810 95,954,987 RGD:1624291
G Elp5 elongator acetyltransferase complex subunit 5 JBrowse link 10 56,578,980 56,590,706 RGD:1600115
G Elp6 elongator acetyltransferase complex subunit 6 JBrowse link 8 118,525,770 118,541,074 RGD:1624291
G Kti12 KTI12 chromatin associated homolog JBrowse link 5 128,464,035 128,465,557 RGD:13792537
G LOC365839 similar to elongation protein 4 homolog JBrowse link 2 186,630,203 186,631,703 RGD:1600115

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  cellular_component 19951
    protein-containing complex 5828
      Elongator holoenzyme complex 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.