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ONTOLOGY REPORT - ANNOTATIONS


Term:indoleamine 2,3-dioxygenase activity
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Accession:GO:0033754 term browser browse the term
Definition:Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.
Synonyms:narrow_synonym: D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity
 broad_synonym: tryptophan pyrrolase activity
 related_synonym: IDO
 xref: EC:1.13.11.52;   MetaCyc:RXN-8664;   MetaCyc:RXN-8665


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indoleamine 2,3-dioxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:2290190
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2290313
RGD:2290543
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:1600115
RGD:1624291
RGD:13792537

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  molecular_function 19619
    catalytic activity 6006
      oxidoreductase activity 844
        dioxygenase activity 79
          oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 27
            indoleamine 2,3-dioxygenase activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.