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ONTOLOGY REPORT - ANNOTATIONS


Term:maintenance of mitotic sister chromatid cohesion
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Accession:GO:0034088 term browser browse the term
Definition:The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
Synonyms:related_synonym: mitotic cohesion stability


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maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dscc1 DNA replication and sister chromatid cohesion 1 ISO
IBA
(PMID:16682347), (PMID:19907496)
PMID:21873635
RGD PMID:16682347, PMID:19907496, PMID:21873635 RGD:13792537 NCBI chr 7:94,759,076...94,774,787
Ensembl chr 7:94,758,800...94,774,569
JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor ISO
IBA
(PMID:16682347), (PMID:16802858)
PMID:21873635
RGD PMID:16682347, PMID:16802858, PMID:21873635 RGD:13792537 NCBI chr16:21,132,115...21,163,257
Ensembl chr16:21,132,147...21,163,257
JBrowse link
G Nipbl NIPBL, cohesin loading factor ISO (PMID:16682347) RGD PMID:16682347 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO
IEA
(PMID:20551165)
GO_REF:0000107
RGD
Ensembl
PMID:20551165 GO_REF:0000107 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit ISO (PMID:27422821) RGD PMID:27422821 NCBI chr  X:156,863,655...156,868,950
Ensembl chr  X:156,863,754...156,868,950
JBrowse link
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler ISO
IEA
(PMID:26373281)
GO_REF:0000107
RGD
Ensembl
PMID:26373281 GO_REF:0000107 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Tnks tankyrase ISO (PMID:26373281) RGD PMID:26373281 NCBI chr16:60,925,093...61,067,192
Ensembl chr16:60,925,093...61,067,192
JBrowse link
positive regulation of maintenance of mitotic sister chromatid cohesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone ISO (PMID:26373281) RGD PMID:26373281 NCBI chr17:9,282,109...9,344,698
Ensembl chr17:9,282,675...9,344,678
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase ISO
ISS
(PMID:19502785)
GO_REF:0000024
RGD
UniProt
PMID:19502785 GO_REF:0000024 NCBI chr 7:99,677,295...99,900,765
Ensembl chr 7:99,677,290...99,900,764
JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 2:4,095,126...4,195,819
Ensembl chr 2:4,095,129...4,195,810
JBrowse link
G Slf2 SMC5-SMC6 complex localization factor 2 ISO (PMID:25931565) RGD PMID:25931565 NCBI chr 1:264,670,836...264,733,465
Ensembl chr 1:264,670,841...264,733,306
JBrowse link
G Smc5 structural maintenance of chromosomes 5 ISO (PMID:19502785) RGD PMID:19502785 NCBI chr 1:240,977,898...241,046,273
Ensembl chr 1:240,977,898...241,046,256
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell cycle process 1210
        maintenance of sister chromatid cohesion 13
          maintenance of mitotic sister chromatid cohesion 12
            maintenance of mitotic sister chromatid cohesion, arms + 0
            maintenance of mitotic sister chromatid cohesion, centromeric + 1
            maintenance of mitotic sister chromatid cohesion, telomeric + 2
            negative regulation of maintenance of mitotic sister chromatid cohesion + 3
            positive regulation of maintenance of mitotic sister chromatid cohesion + 5
            regulation of maintenance of mitotic sister chromatid cohesion + 8
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          organelle organization 4101
            organelle fission 500
              nuclear division 445
                mitotic nuclear division 283
                  mitotic sister chromatid segregation 158
                    mitotic sister chromatid cohesion 29
                      maintenance of mitotic sister chromatid cohesion 12
                        maintenance of mitotic sister chromatid cohesion, arms + 0
                        maintenance of mitotic sister chromatid cohesion, centromeric + 1
                        maintenance of mitotic sister chromatid cohesion, telomeric + 2
                        negative regulation of maintenance of mitotic sister chromatid cohesion + 3
                        positive regulation of maintenance of mitotic sister chromatid cohesion + 5
                        regulation of maintenance of mitotic sister chromatid cohesion + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.