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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of toll-like receptor signaling pathway
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Accession:GO:0034122 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
Synonyms:exact_synonym: negative regulation of TLR signaling pathway;   negative regulation of toll-like receptor signalling pathway


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negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
G Cactin cactin, spliceosome C complex subunit JBrowse link 7 11,258,526 11,266,509 RGD:1624291
G Gps2 G protein pathway suppressor 2 JBrowse link 10 56,524,327 56,527,447 RGD:1624291
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 7 64,922,830 64,982,224 RGD:1624291
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:1624291
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 JBrowse link 3 101,051,960 101,152,119 RGD:1624291
RGD:1600115
G Lrrc14 leucine rich repeat containing 14 JBrowse link 7 117,773,219 117,779,555 RGD:1600115
RGD:1624291
G Nfkbil1 NFKB inhibitor like 1 JBrowse link 20 4,823,590 4,839,202 RGD:1624291
RGD:13792537
RGD:1600115
G Nlrp6 NLR family, pyrin domain containing 6 JBrowse link 1 213,676,954 213,683,114 RGD:1624291
G Otud4 OTU deubiquitinase 4 JBrowse link 19 31,895,753 31,942,509 RGD:1624291
RGD:13792537
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:1624291
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 1 260,527,344 260,679,132 RGD:1624291
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B JBrowse link 5 150,925,150 150,946,994 RGD:1624291
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Tyro3 TYRO3 protein tyrosine kinase JBrowse link 3 111,597,102 111,616,142 RGD:1600115
RGD:1624291
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Cd300lf Cd300 molecule-like family member F JBrowse link 10 103,669,781 103,690,584 RGD:1624291
RGD:1600115
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sarm1 sterile alpha and TIR motif containing 1 JBrowse link 10 65,742,343 65,766,050 RGD:1600115
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acod1 aconitate decarboxylase 1 JBrowse link 15 93,612,968 93,622,322 RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:1600115
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 JBrowse link 16 60,120,457 60,208,550 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1624291
RGD:1600115
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acod1 aconitate decarboxylase 1 JBrowse link 15 93,612,968 93,622,322 RGD:1624291
G Bpifb1 BPI fold containing family B, member 1 JBrowse link 3 149,668,099 149,702,399 RGD:1624291
RGD:13792537
RGD:1600115
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:1600115
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 JBrowse link 16 60,120,457 60,208,550 RGD:1624291
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:1624291
RGD:1600115
G Rab7b Rab7b, member RAS oncogene family JBrowse link 13 48,456,143 48,483,714 RGD:1624291
G Ticam2 toll-like receptor adaptor molecule 2 JBrowse link 18 40,555,106 40,572,569 RGD:1624291
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gramd4 GRAM domain containing 4 JBrowse link 7 126,939,819 127,013,455 RGD:1624291
RGD:13792537
G Ptprs protein tyrosine phosphatase, receptor type, S JBrowse link 9 10,585,360 10,646,205 RGD:1600115
RGD:1624291
G Rab7b Rab7b, member RAS oncogene family JBrowse link 13 48,456,143 48,483,714 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      negative regulation of signaling 1396
        negative regulation of signal transduction 1232
          negative regulation of toll-like receptor signaling pathway 33
            negative regulation of MyD88-dependent toll-like receptor signaling pathway 2
            negative regulation of MyD88-independent toll-like receptor signaling pathway 1
            negative regulation of toll-like receptor 1 signaling pathway 0
            negative regulation of toll-like receptor 10 signaling pathway 0
            negative regulation of toll-like receptor 11 signaling pathway 0
            negative regulation of toll-like receptor 12 signaling pathway 0
            negative regulation of toll-like receptor 13 signaling pathway 0
            negative regulation of toll-like receptor 15 signaling pathway 0
            negative regulation of toll-like receptor 2 signaling pathway 5
            negative regulation of toll-like receptor 21 signaling pathway 0
            negative regulation of toll-like receptor 3 signaling pathway 3
            negative regulation of toll-like receptor 4 signaling pathway 8
            negative regulation of toll-like receptor 5 signaling pathway 1
            negative regulation of toll-like receptor 6 signaling pathway 0
            negative regulation of toll-like receptor 7 signaling pathway 0
            negative regulation of toll-like receptor 8 signaling pathway 0
            negative regulation of toll-like receptor 9 signaling pathway 3
            suppression by virus of host toll-like receptor signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            regulation of signal transduction 2973
              regulation of pattern recognition receptor signaling pathway 90
                regulation of toll-like receptor signaling pathway 62
                  negative regulation of toll-like receptor signaling pathway 33
                    negative regulation of MyD88-dependent toll-like receptor signaling pathway 2
                    negative regulation of MyD88-independent toll-like receptor signaling pathway 1
                    negative regulation of toll-like receptor 1 signaling pathway 0
                    negative regulation of toll-like receptor 10 signaling pathway 0
                    negative regulation of toll-like receptor 11 signaling pathway 0
                    negative regulation of toll-like receptor 12 signaling pathway 0
                    negative regulation of toll-like receptor 13 signaling pathway 0
                    negative regulation of toll-like receptor 15 signaling pathway 0
                    negative regulation of toll-like receptor 2 signaling pathway 5
                    negative regulation of toll-like receptor 21 signaling pathway 0
                    negative regulation of toll-like receptor 3 signaling pathway 3
                    negative regulation of toll-like receptor 4 signaling pathway 8
                    negative regulation of toll-like receptor 5 signaling pathway 1
                    negative regulation of toll-like receptor 6 signaling pathway 0
                    negative regulation of toll-like receptor 7 signaling pathway 0
                    negative regulation of toll-like receptor 8 signaling pathway 0
                    negative regulation of toll-like receptor 9 signaling pathway 3
                    suppression by virus of host toll-like receptor signaling pathway 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.