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ONTOLOGY REPORT - ANNOTATIONS


Term:toll-like receptor 2 signaling pathway
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Accession:GO:0034134 term browser browse the term
Definition:Any series of molecular signals generated as a consequence of binding to toll-like receptor 2.
Synonyms:exact_synonym: TLR2 signaling pathway;   toll-like receptor 2 signalling pathway


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toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO
IBA
(PMID:10383454)
PMID:21873635
(MGI:2178646|PMID:10549626)
RGD PMID:10383454 PMID:10549626, PMID:21873635 MGI:2178646, RGD:13792537 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Lgals9 galectin 9 NOT ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO (MGI:5305503|PMID:22187460) RGD PMID:22187460 MGI:5305503 NCBI chr 1:260,527,344...260,679,132
Ensembl chr 1:260,527,781...260,638,915
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 ISO (PMID:11894098) RGD PMID:11894098 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G Tlr2 toll-like receptor 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 ISO
IBA
(MGI:3656197|PMID:16633345)
PMID:21873635
RGD PMID:16633345, PMID:21873635 MGI:3656197, RGD:13792537 NCBI chr14:81,487,934...81,505,889
Ensembl chr14:81,488,008...81,504,686
JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:93,612,968...93,622,322
Ensembl chr15:93,612,971...93,622,358
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISS
ISO
GO_REF:0000024
(MGI:4456928|PMID:20385881)
UniProt
RGD
PMID:20385881 GO_REF:0000024 MGI:4456928 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 ISO (PMID:26599367)
(MGI:6162316|PMID:26599367)
RGD PMID:26599367 MGI:6162316 NCBI chr16:60,120,457...60,208,550
Ensembl chr16:60,128,201...60,208,462
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO MGI:2680581 (MGI:3050756|PMID:15220916) RGD PMID:15220916 MGI:3050756 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Tlr6 toll-like receptor 6 ISO ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949) RGD PMID:22198949 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446
JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain ISO (PMID:22423966) RGD PMID:22423966 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO (PMID:19865078) RGD PMID:19865078 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Hmgb1 high mobility group box 1 ISO (MGI:5788395|PMID:16267105) RGD PMID:16267105 MGI:5788395 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 ISO (PMID:26599367), (PMID:28471450)
(MGI:6162316|PMID:26599367)
RGD PMID:26599367 PMID:28471450 MGI:6162316 NCBI chr16:60,120,457...60,208,550
Ensembl chr16:60,128,201...60,208,462
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 ISS
ISO
GO_REF:0000024
(PMID:28471450)
UniProt
RGD
PMID:28471450 GO_REF:0000024 NCBI chr 9:111,998,204...112,048,847
Ensembl chr 9:111,998,203...112,027,240
JBrowse link
G Tirap TIR domain containing adaptor protein ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tlr1 toll-like receptor 1 ISO ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949) RGD PMID:22198949 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    signaling 7581
      signal transduction 7012
        pattern recognition receptor signaling pathway 160
          toll-like receptor signaling pathway 110
            toll-like receptor 2 signaling pathway 17
              MyD88-dependent toll-like receptor 2 signaling pathway 0
              negative regulation of toll-like receptor 2 signaling pathway 5
              positive regulation of toll-like receptor 2 signaling pathway 7
              regulation of toll-like receptor 2 signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 20030
    biological regulation 13774
      regulation of biological process 13076
        regulation of cellular process 12564
          signal transduction 7012
            pattern recognition receptor signaling pathway 160
              toll-like receptor signaling pathway 110
                toll-like receptor 2 signaling pathway 17
                  MyD88-dependent toll-like receptor 2 signaling pathway 0
                  negative regulation of toll-like receptor 2 signaling pathway 5
                  positive regulation of toll-like receptor 2 signaling pathway 7
                  regulation of toll-like receptor 2 signaling pathway + 11
paths to the root