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ONTOLOGY REPORT - ANNOTATIONS


Term:macrophage fusion
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Accession:GO:0034238 term browser browse the term
Definition:The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.


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macrophage fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) IMP RGD PMID:16195325 RGD:2289375 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd81 Cd81 molecule ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:2663571|PMID:12796480)
(PMID:12796480)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12796480 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2663571 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
negative regulation of macrophage fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stat1 signal transducer and activator of transcription 1 ISO MGI:MGI:1861949 (MGI:MGI:5462143|PMID:22865856) RGD PMID:22865856 MGI:MGI:5462143 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
positive regulation of macrophage fusion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 ISO (PMID:11831872) RGD PMID:11831872 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein ISO MGI:MGI:1921864 (MGI:MGI:3588832|PMID:16061724), (MGI:MGI:5426135|PMID:16937266), (MGI:MGI:5462143|PMID:22865856) RGD PMID:16061724, PMID:16937266, PMID:22865856 MGI:MGI:3588832, MGI:MGI:5426135, MGI:MGI:5462143 NCBI chr 7:78,642,016...78,651,763
Ensembl chr 7:78,649,875...78,650,906
JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein ISO MGI:MGI:1923016 (MGI:MGI:5462143|PMID:22865856) RGD PMID:22865856 MGI:MGI:5462143 NCBI chr 3:162,073,573...162,080,487
Ensembl chr 3:162,075,340...162,080,192
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 ISO (MGI:MGI:6142486|PMID:18957693) RGD PMID:18957693 MGI:MGI:6142486 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp ISO
IBA
(PMID:18957693)
PMID:21873635
(MGI:MGI:6142486|PMID:18957693)
RGD PMID:18957693, PMID:21873635 MGI:MGI:6142486, RGD:13792537 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      syncytium formation 66
        syncytium formation by plasma membrane fusion 64
          macrophage fusion 8
            negative regulation of macrophage fusion 1
            positive regulation of macrophage fusion 5
            regulation of macrophage fusion + 6
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        anatomical structure morphogenesis 2877
          anatomical structure formation involved in morphogenesis 1213
            syncytium formation 66
              syncytium formation by plasma membrane fusion 64
                macrophage fusion 8
                  negative regulation of macrophage fusion 1
                  positive regulation of macrophage fusion 5
                  regulation of macrophage fusion + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.