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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transcription elongation from RNA polymerase II promoter
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Accession:GO:0034244 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
Synonyms:exact_synonym: negative regulation of RNA elongation from RNA polymerase II promoter
 related_synonym: negative regulation of gene-specific transcription elongation from RNA polymerase II promoter
 alt_id: GO:0090041


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negative regulation of transcription elongation from RNA polymerase II promoter term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 ISO (MGI:MGI:1336856|PMID:10318824), (MGI:MGI:3840033|PMID:19204372) RGD PMID:10318824, PMID:19204372 MGI:MGI:1336856, MGI:MGI:3840033
G Eapp E2F-associated phosphoprotein ISO (PMID:15716352) RGD PMID:15716352 NCBI chr 6:75,561,898...75,589,274
Ensembl chr 6:75,567,511...75,589,257
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO MGI:MGI:2661097 (MGI:MGI:3846264|PMID:19303854) RGD PMID:19303854 MGI:MGI:3846264 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U IEA
ISO
GO_REF:0000107
(PMID:10490622)
Ensembl
RGD
PMID:10490622 GO_REF:0000107 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Nelfa negative elongation factor complex member A ISO
IBA
(MGI:MGI:5014448|PMID:21670248)
PMID:21873635
RGD PMID:21670248, PMID:21873635 MGI:MGI:5014448, RGD:13792537 NCBI chr14:82,093,837...82,117,913
Ensembl chr14:82,093,837...82,117,906
JBrowse link
G Nelfb negative elongation factor complex member B IBA
ISO
PMID:21873635
(MGI:MGI:3845453|PMID:19340312), (MGI:MGI:5576446|PMID:24656816), (MGI:MGI:6270977|PMID:25773599)
RGD PMID:19340312, PMID:24656816, PMID:25773599, PMID:21873635 MGI:MGI:3845453, MGI:MGI:5576446, MGI:MGI:6270977, RGD:13792537 NCBI chr 3:2,414,448...2,431,148
Ensembl chr 3:2,414,451...2,431,148
JBrowse link
G Nelfcd negative elongation factor complex member C/D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:172,510,840...172,527,118
Ensembl chr 3:172,510,874...172,526,740
JBrowse link
G Nelfe negative elongation factor complex member E ISO
IBA
(MGI:MGI:5014448|PMID:21670248)
PMID:21873635
RGD PMID:21670248, PMID:21873635 MGI:MGI:5014448, RGD:13792537 NCBI chr20:4,530,328...4,536,085
Ensembl chr20:4,530,342...4,536,209
JBrowse link
G Recql5 RecQ like helicase 5 ISO
ISS
(PMID:23748380)
GO_REF:0000024
RGD
UniProt
PMID:23748380 GO_REF:0000024 NCBI chr10:104,443,735...104,482,889
Ensembl chr10:104,443,736...104,482,838
JBrowse link
G Rnf168 ring finger protein 168 ISO
IEA
ISS
(PMID:20550933)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20550933 GO_REF:0000024, GO_REF:0000107 NCBI chr11:71,721,242...71,743,421
Ensembl chr11:71,721,250...71,743,421
JBrowse link
G Rnf8 ring finger protein 8 ISO
ISS
(PMID:20550933)
GO_REF:0000024
RGD
UniProt
PMID:20550933 GO_REF:0000024 NCBI chr20:8,285,380...8,309,858
Ensembl chr20:8,285,296...8,309,908
JBrowse link
G Shh sonic hedgehog signaling molecule ISO
IEA
(MGI:MGI:3703195|PMID:17284610)
GO_REF:0000107
RGD
Ensembl
PMID:17284610 GO_REF:0000107, MGI:MGI:3703195 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit ISO (MGI:MGI:5014448|PMID:21670248) RGD PMID:21670248 MGI:MGI:5014448 NCBI chr10:75,032,365...75,038,547
Ensembl chr10:75,032,365...75,038,547
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      negative regulation of metabolic process 3311
        negative regulation of macromolecule metabolic process 3047
          negative regulation of gene expression 2169
            negative regulation of transcription, DNA-templated 1346
              negative regulation of DNA-templated transcription, elongation 15
                negative regulation of transcription elongation from RNA polymerase II promoter 13
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA biosynthetic process 3477
                  nucleic acid-templated transcription 3463
                    transcription, DNA-templated 3418
                      transcription by RNA polymerase II 2508
                        transcription elongation from RNA polymerase II promoter 72
                          regulation of transcription elongation from RNA polymerase II promoter 38
                            negative regulation of transcription elongation from RNA polymerase II promoter 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.