ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Arp2/3 complex-mediated actin nucleation
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Accession:GO:0034316 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.


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negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coro1b coronin 1B JBrowse link 1 219,397,827 219,403,253 RGD:1624291
RGD:1600115
G Ctnna2 catenin alpha 2 JBrowse link 4 107,880,611 109,042,724 RGD:1624291
G Gmfb glia maturation factor, beta JBrowse link 15 23,597,846 23,611,541 RGD:1600115
RGD:13792537
G Gmfg glia maturation factor, gamma JBrowse link 1 85,312,473 85,322,860 RGD:1624291
RGD:13792537
RGD:1600115
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:1624291
RGD:1600115
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:8554748

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    cellular process 16077
      cellular component organization 6054
        negative regulation of cellular component organization 757
          negative regulation of supramolecular fiber organization 151
            negative regulation of actin nucleation 8
              negative regulation of Arp2/3 complex-mediated actin nucleation 6
Path 2
Term Annotations click to browse term
  biological_process 17926
    biological regulation 12622
      regulation of biological process 11964
        regulation of cellular process 11300
          regulation of cellular component organization 2538
            regulation of organelle organization 1278
              regulation of cytoskeleton organization 547
                regulation of actin cytoskeleton organization 346
                  regulation of actin filament length 180
                    regulation of actin polymerization or depolymerization 178
                      regulation of actin filament polymerization 161
                        positive regulation of actin filament polymerization 95
                          actin nucleation 45
                            Arp2/3 complex-mediated actin nucleation 33
                              regulation of Arp2/3 complex-mediated actin nucleation 16
                                negative regulation of Arp2/3 complex-mediated actin nucleation 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.