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ONTOLOGY REPORT - ANNOTATIONS


Term:response to type I interferon
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Accession:GO:0034340 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms:exact_synonym: response to type I IFN


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response to type I interferon term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon IEA Ensembl GO_REF:0000107 NCBI chr 1:206,470,243...206,496,890
Ensembl chr 1:206,470,476...206,496,889
JBrowse link
G ISG15 ISG15 ubiquitin like modifier IDA (PMID:22859821) UniProtKB PMID:22859821 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
JBrowse link
G MX1 MX dynamin like GTPase 1 TAS (PMID:21859714) UniProtKB PMID:21859714 NCBI chr21:41,420,329...41,459,214
Ensembl chr21:41,420,304...41,459,214
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase IDA (PMID:28753426) UniProtKB PMID:28753426 NCBI chr 3:47,016,431...47,164,113
Ensembl chr 3:47,016,429...47,164,113
Ensembl chr 3:47,016,429...47,164,113
JBrowse link
G SHFL shiftless antiviral inhibitor of ribosomal frameshifting IDA (PMID:26735137) UniProtKB PMID:26735137 NCBI chr19:10,086,119...10,093,249
Ensembl chr19:10,086,122...10,093,252
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 IDA
IBA
(PMID:24075985)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24075985 NCBI chr12:57,229,685...57,234,935
Ensembl chr12:57,229,573...57,234,935
JBrowse link
G SP100 SP100 nuclear antigen IMP
IDA
(PMID:8810287)
(PMID:15247905), (PMID:16873258), (PMID:9230084)
BHF-UCL PMID:8810287, PMID:9230084, PMID:15247905, PMID:16873258 NCBI chr 2:230,416,201...230,545,606
Ensembl chr 2:230,415,942...230,545,606
JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO (MGI:MGI:5645191|PMID:24882218) UniProtKB PMID:24882218 MGI:MGI:5645191 NCBI chr 2:190,968,989...191,014,197
Ensembl chr 2:190,908,460...191,020,960
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G TRIM56 tripartite motif containing 56 ISS UniProtKB GO_REF:0000024 NCBI chr 7:101,085,424...101,097,967
Ensembl chr 7:101,085,481...101,097,967
JBrowse link
cellular response to type I interferon term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A7 cytochrome P450 family 3 subfamily A member 7 ISO (PMID:24525126) AgBase PMID:24525126 NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 IDA (PMID:19008854) BHF-UCL PMID:19008854 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487
JBrowse link
G MX1 MX dynamin like GTPase 1 ISO (PMID:24500530) AgBase PMID:24500530 NCBI chr21:41,420,329...41,459,214
Ensembl chr21:41,420,304...41,459,214
JBrowse link
G TREX1 three prime repair exonuclease 1 ISO (MGI:MGI:6103025|PMID:28835460) MGI PMID:28835460 MGI:MGI:6103025 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645
JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific IEA Ensembl GO_REF:0000107 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,582,057...154,628,013
JBrowse link
G CACTIN cactin, spliceosome C complex subunit IMP (PMID:20829348) UniProtKB PMID:20829348 NCBI chr19:3,610,645...3,626,810
Ensembl chr19:3,610,645...3,626,815
JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 IMP (PMID:23386060) UniProtKB PMID:23386060 NCBI chr 8:17,221,981...17,246,857
Ensembl chr 8:17,224,966...17,246,878
JBrowse link
G DCST1 DC-STAMP domain containing 1 IMP (PMID:27782195) UniProtKB PMID:27782195 NCBI chr 1:155,033,806...155,050,930
Ensembl chr 1:155,033,824...155,050,930
JBrowse link
G METTL3 methyltransferase like 3 IMP (PMID:30559377) UniProt PMID:30559377 NCBI chr14:21,498,138...21,511,340
Ensembl chr14:21,498,133...21,511,342
JBrowse link
G MMP12 matrix metallopeptidase 12 IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 IMP (PMID:23399697) UniProtKB PMID:23399697 NCBI chr 1:20,499,448...20,508,483
Ensembl chr 1:20,499,448...20,508,151
JBrowse link
G NLRC5 NLR family CARD domain containing 5 IDA
IBA
(PMID:20434986)
(PMID:21873635)
UniProtKB
GO_Central
PMID:20434986, PMID:21873635 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 IMP (PMID:11909529) UniProtKB PMID:11909529 NCBI chr18:12,785,478...12,884,351
Ensembl chr18:12,785,478...12,929,643
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 IDA (PMID:29670289) UniProtKB PMID:29670289 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,889,773...36,951,901
Ensembl chr20:36,889,773...36,951,901
JBrowse link
G TREX1 three prime repair exonuclease 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645
JBrowse link
G TTLL12 tubulin tyrosine ligase like 12 IMP (PMID:28011935) UniProt PMID:28011935 NCBI chr22:43,166,622...43,187,134
Ensembl chr22:43,166,622...43,187,134
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 IMP (PMID:30559377) UniProt PMID:30559377 NCBI chr 1:28,736,624...28,769,775
Ensembl chr 1:28,736,621...28,769,775
JBrowse link
G YTHDF3 YTH N6-methyladenosine RNA binding protein 3 IEA
ISS
Ensembl
UniProt
GO_REF:0000024, GO_REF:0000107 NCBI chr 8:63,168,553...63,212,788
Ensembl chr 8:63,168,553...63,212,786
JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain IMP (PMID:21109225) UniProtKB PMID:21109225 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,163...70,207,390
Ensembl chr11:70,203,163...70,207,390
JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon IEA Ensembl GO_REF:0000107 NCBI chr 1:206,470,243...206,496,890
Ensembl chr 1:206,470,476...206,496,889
JBrowse link
G IRF3 interferon regulatory factor 3 IEA Ensembl GO_REF:0000107 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF7 interferon regulatory factor 7 IEA Ensembl GO_REF:0000107 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor IEA Ensembl GO_REF:0000107 NCBI chr19:34,172,499...34,229,288
Ensembl chr19:34,172,504...34,229,515
JBrowse link
G MAVS mitochondrial antiviral signaling protein IDA (PMID:16127453), (PMID:20451243) BHF-UCL PMID:16127453, PMID:20451243 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
JBrowse link
G MMP12 matrix metallopeptidase 12 IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G NLRC5 NLR family CARD domain containing 5 IDA (PMID:20061403) UniProtKB PMID:20061403 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531
JBrowse link
G TBK1 TANK binding kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr12:64,452,105...64,502,114
Ensembl chr12:64,452,092...64,502,114
JBrowse link
G TRIM6 tripartite motif containing 6 IMP (PMID:24882218) UniProtKB PMID:24882218 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958
JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K IMP (PMID:24882218) UniProtKB PMID:24882218 NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792
JBrowse link
G WNT5A Wnt family member 5A IDA (PMID:19399181) BHF-UCL PMID:19399181 NCBI chr 3:55,465,715...55,505,261
Ensembl chr 3:55,465,715...55,490,539
JBrowse link
G ZBP1 Z-DNA binding protein 1 IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr20:57,603,852...57,620,480
Ensembl chr20:57,603,846...57,620,576
JBrowse link
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCE1 ATP binding cassette subfamily E member 1 TAS Reactome Reactome:R-HSA-5223305 NCBI chr 4:145,098,311...145,129,524
Ensembl chr 4:145,098,288...145,129,524
JBrowse link
G CDC37 cell division cycle 37, HSP90 cochaperone IMP (PMID:16280321) MGI PMID:16280321 NCBI chr19:10,391,128...10,403,568
Ensembl chr19:10,391,133...10,420,121
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 IMP (PMID:16280321) MGI PMID:16280321 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G IFNAR2 interferon alpha and beta receptor subunit 2 TAS Reactome Reactome:R-HSA-912694 NCBI chr21:33,229,938...33,265,664
Ensembl chr21:33,229,901...33,297,160
Ensembl chr21:33,229,901...33,297,160
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 TAS Reactome Reactome:R-HSA-912694 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 TAS Reactome Reactome:R-HSA-912694 NCBI chr12:112,418,915...112,509,918
Ensembl chr12:112,418,351...112,509,913
Ensembl chr12:112,418,351...112,509,913
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 TAS Reactome Reactome:R-HSA-912694 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316
JBrowse link
G RNASEL ribonuclease L TAS Reactome Reactome:R-HSA-5223305 NCBI chr 1:182,573,634...182,589,285
Ensembl chr 1:182,573,634...182,589,256
JBrowse link
G USP18 ubiquitin specific peptidase 18 TAS Reactome Reactome:R-HSA-912694 NCBI chr22:18,149,855...18,177,397
Ensembl chr22:18,150,170...18,177,397
JBrowse link
type I interferon signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific TAS Reactome Reactome:R-HSA-909733 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,582,057...154,628,013
JBrowse link
G BST2 bone marrow stromal cell antigen 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630
JBrowse link
G EGR1 early growth response 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G GBP2 guanylate binding protein 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456
JBrowse link
G HLA-A major histocompatibility complex, class I, A TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,945,884
JBrowse link
G HLA-B major histocompatibility complex, class I, B TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,269,491...31,357,188
JBrowse link
G HLA-C major histocompatibility complex, class I, C TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130
JBrowse link
G HLA-E major histocompatibility complex, class I, E TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:30,489,508...30,494,194
Ensembl chr 6:30,489,509...30,494,194
JBrowse link
G HLA-F major histocompatibility complex, class I, F TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:29,723,434...29,740,355
Ensembl chr 6:29,722,775...29,738,528
JBrowse link
G HLA-G major histocompatibility complex, class I, G TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:29,826,474...29,831,130
Ensembl chr 6:29,826,967...29,831,125
JBrowse link
G HLA-H major histocompatibility complex, class I, H (pseudogene) TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:29,887,573...29,891,079
Ensembl chr 6:29,887,752...29,890,482
JBrowse link
G IFI27 interferon alpha inducible protein 27 TAS
IMP
(PMID:27777077) Reactome
UniProt
PMID:27777077 Reactome:R-HSA-909733 NCBI chr14:94,110,736...94,116,690
Ensembl chr14:94,104,836...94,116,698
JBrowse link
G IFI35 interferon induced protein 35 TAS Reactome Reactome:R-HSA-909733 NCBI chr17:43,006,784...43,014,459
Ensembl chr17:43,006,725...43,014,456
Ensembl chr17:43,006,725...43,014,456
JBrowse link
G IFI6 interferon alpha inducible protein 6 TAS Reactome Reactome:R-HSA-909733 NCBI chr 1:27,666,061...27,672,229
Ensembl chr 1:27,666,064...27,672,198
JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487
JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 TAS Reactome Reactome:R-HSA-909733 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,997...89,340,971
JBrowse link
G IFITM1 interferon induced transmembrane protein 1 TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-909733 NCBI chr11:314,040...315,272
Ensembl chr11:313,506...315,272
JBrowse link
G IFITM2 interferon induced transmembrane protein 2 TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-909733 NCBI chr11:308,107...309,410
Ensembl chr11:307,631...315,272
JBrowse link
G IFITM3 interferon induced transmembrane protein 3 TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-909733 NCBI chr11:319,676...320,860
Ensembl chr11:319,676...327,537
JBrowse link
G IFNA1 interferon alpha 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316
JBrowse link
G IFNA10 interferon alpha 10 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,206,181...21,207,143
Ensembl chr 9:21,206,181...21,207,143
JBrowse link
G IFNA13 interferon alpha 13 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,367,372...21,368,057
Ensembl chr 9:21,367,424...21,368,962
JBrowse link
G IFNA14 interferon alpha 14 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,239,002...21,240,005
Ensembl chr 9:21,239,002...21,240,005
JBrowse link
G IFNA16 interferon alpha 16 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,216,373...21,217,311
Ensembl chr 9:21,216,373...21,217,311
JBrowse link
G IFNA17 interferon alpha 17 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,227,243...21,228,222
Ensembl chr 9:21,227,243...21,228,222
JBrowse link
G IFNA2 interferon alpha 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IFNA21 interferon alpha 21 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,165,637...21,166,660
Ensembl chr 9:21,165,637...21,166,660
JBrowse link
G IFNA4 interferon alpha 4 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,186,618...21,187,682
Ensembl chr 9:21,186,694...21,187,671
JBrowse link
G IFNA5 interferon alpha 5 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,304,326...21,305,313
Ensembl chr 9:21,304,326...21,305,312
JBrowse link
G IFNA6 interferon alpha 6 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,350,318...21,350,887
Ensembl chr 9:21,349,835...21,351,378
JBrowse link
G IFNA7 interferon alpha 7 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,201,469...21,202,205
Ensembl chr 9:21,201,469...21,202,205
JBrowse link
G IFNA8 interferon alpha 8 TAS Reactome Reactome:R-HSA-909733 NCBI chr 9:21,409,117...21,410,185
Ensembl chr 9:21,409,117...21,410,185
JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 TAS
IDA
(PMID:7665574) Reactome
UniProtKB
PMID:7665574 Reactome:R-HSA-909733 NCBI chr21:33,324,395...33,359,864
Ensembl chr21:33,324,429...33,359,864
JBrowse link
G IFNAR2 interferon alpha and beta receptor subunit 2 TAS
IBA
IDA
IMP
(PMID:21873635)
(PMID:7665574)
(PMID:26424569)
Reactome
GO_Central
UniProtKB
PMID:7665574, PMID:21873635, PMID:26424569 Reactome:R-HSA-909733 NCBI chr21:33,229,938...33,265,664
Ensembl chr21:33,229,901...33,297,160
Ensembl chr21:33,229,901...33,297,160
JBrowse link
G IFNB1 interferon beta 1 IDA
TAS
(PMID:18035482) BHF-UCL
Reactome
PMID:18035482 Reactome:R-HSA-909733 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
JBrowse link
G IP6K2 inositol hexakisphosphate kinase 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr 3:48,688,003...48,717,258
Ensembl chr 3:48,688,003...48,740,353
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 IMP (PMID:23633945) BHF-UCL PMID:23633945 NCBI chr  X:154,010,507...154,019,984
Ensembl chr  X:154,010,506...154,019,902
JBrowse link
G IRF1 interferon regulatory factor 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr 5:132,481,609...132,490,789
Ensembl chr 5:132,481,609...132,490,777
JBrowse link
G IRF2 interferon regulatory factor 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr 4:184,382,741...184,474,580
Ensembl chr 4:184,387,729...184,474,550
JBrowse link
G IRF3 interferon regulatory factor 3 TAS Reactome Reactome:R-HSA-909733 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF4 interferon regulatory factor 4 TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,752...411,443
JBrowse link
G IRF5 interferon regulatory factor 5 TAS Reactome Reactome:R-HSA-909733 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
JBrowse link
G IRF6 interferon regulatory factor 6 TAS Reactome Reactome:R-HSA-909733 NCBI chr 1:209,785,617...209,806,142
Ensembl chr 1:209,785,617...209,806,175
JBrowse link
G IRF7 interferon regulatory factor 7 TAS Reactome Reactome:R-HSA-909733 NCBI chr11:612,555...615,999
Ensembl chr11:612,553...615,983
JBrowse link
G IRF8 interferon regulatory factor 8 TAS Reactome Reactome:R-HSA-909733 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,162...85,922,606
JBrowse link
G IRF9 interferon regulatory factor 9 TAS Reactome Reactome:R-HSA-909733 NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,265...24,166,565
JBrowse link
G ISG15 ISG15 ubiquitin like modifier TAS Reactome Reactome:R-HSA-909733 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
JBrowse link
G ISG20 interferon stimulated exonuclease gene 20 TAS Reactome Reactome:R-HSA-909733 NCBI chr15:88,635,614...88,656,483
Ensembl chr15:88,636,153...88,656,483
JBrowse link
G JAK1 Janus kinase 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,229...65,067,754
JBrowse link
G MX1 MX dynamin like GTPase 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr21:41,420,329...41,459,214
Ensembl chr21:41,420,304...41,459,214
JBrowse link
G MX2 MX dynamin like GTPase 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr21:41,361,944...41,409,393
Ensembl chr21:41,361,999...41,409,393
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IMP (PMID:23633945) BHF-UCL PMID:23633945 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,478...38,143,022
JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr12:112,906,956...112,933,219
Ensembl chr12:112,906,783...112,933,222
JBrowse link
G OAS2 2'-5'-oligoadenylate synthetase 2 TAS
ISS
Reactome
UniProtKB
GO_REF:0000024, Reactome:R-HSA-909733 NCBI chr12:112,978,466...113,011,723
Ensembl chr12:112,978,395...113,011,723
JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 TAS Reactome Reactome:R-HSA-909733 NCBI chr12:112,938,463...112,973,251
Ensembl chr12:112,938,444...112,973,251
JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like TAS Reactome Reactome:R-HSA-909733 NCBI chr12:121,018,882...121,039,242
Ensembl chr12:121,019,111...121,039,242
JBrowse link
G PSMB8 proteasome 20S subunit beta 8 TAS Reactome Reactome:R-HSA-909733 NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
JBrowse link
G RNASEL ribonuclease L TAS Reactome Reactome:R-HSA-909733 NCBI chr 1:182,573,634...182,589,285
Ensembl chr 1:182,573,634...182,589,256
JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr 2:6,865,733...6,898,239
Ensembl chr 2:6,865,806...6,898,239
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,889,773...36,951,901
Ensembl chr20:36,889,773...36,951,901
JBrowse link
G SP100 SP100 nuclear antigen IC (PMID:8810287) BHF-UCL PMID:8810287 NCBI chr 2:230,416,201...230,545,606
Ensembl chr 2:230,415,942...230,545,606
JBrowse link
G STAT1 signal transducer and activator of transcription 1 TAS
IBA
ISS
IDA
(PMID:21873635)
(PMID:23386060)
Reactome
GO_Central
UniProtKB
PMID:21873635, PMID:23386060 GO_REF:0000024, Reactome:R-HSA-909733 NCBI chr 2:190,968,989...191,014,197
Ensembl chr 2:190,908,460...191,020,960
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G STAT2 signal transducer and activator of transcription 2 TAS
IBA
IMP
(PMID:21873635)
(PMID:23391734)
Reactome
GO_Central
UniProtKB
PMID:21873635, PMID:23391734 Reactome:R-HSA-909733 NCBI chr12:56,341,597...56,360,161
Ensembl chr12:56,341,597...56,360,167
JBrowse link
G TREX1 three prime repair exonuclease 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645
JBrowse link
G TYK2 tyrosine kinase 2 TAS Reactome Reactome:R-HSA-909733 NCBI chr19:10,350,528...10,380,572
Ensembl chr19:10,350,529...10,380,572
JBrowse link
G XAF1 XIAP associated factor 1 TAS Reactome Reactome:R-HSA-909733 NCBI chr17:6,755,408...6,775,647
Ensembl chr17:6,755,447...6,775,647
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    immune system process 3584
      immune response 2465
        innate immune response 1078
          response to type I interferon 99
            cellular response to type I interferon + 95
Path 2
Term Annotations click to browse term
  biological_process 18670
    response to stimulus 10152
      response to biotic stimulus 1952
        response to external biotic stimulus 1915
          response to other organism 1912
            defense response to other organism 1317
              innate immune response 1078
                response to type I interferon 99
                  cellular response to type I interferon + 95
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.