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ONTOLOGY REPORT - ANNOTATIONS


Term:very-low-density lipoprotein particle remodeling
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Accession:GO:0034372 term browser browse the term
Definition:The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms:exact_synonym: VLDL remodeling
 related_synonym: IDL formation;   intermediate-density lipoprotein particle formation


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very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 ISO
IBA
IEA
(PMID:2307668)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:2307668, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoa5 apolipoprotein A5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apoe apolipoprotein E ISO
IEA
(MGI:MGI:3850619|PMID:15654758)
UniProtKB:P08226 (PMID:12401887), (PMID:15654758)
GO_REF:0000107
RGD
Ensembl
PMID:12401887, PMID:15654758 GO_REF:0000107, MGI:MGI:3850619 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Lcat lecithin cholesterol acyltransferase ISO (PMID:15654758) RGD PMID:15654758 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lipc lipase C, hepatic type IDA
IEA
ISO
GO_REF:0000107
(PMID:8640403)
Ensembl
RGD
PMID:8640403, PMID:6791934 GO_REF:0000107, RGD:2308780 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lpl lipoprotein lipase ISO (PMID:3973011) RGD PMID:3973011 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
negative regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 ISO (PMID:14967812) RGD PMID:14967812 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 ISO (PMID:14967812) RGD PMID:14967812 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoc3 apolipoprotein C3 ISO
IEA
(PMID:3973011)
GO_REF:0000107
RGD
Ensembl
PMID:3973011 GO_REF:0000107 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO
IEA
(MGI:MGI:6095248|PMID:27471003)
GO_REF:0000107
(PMID:27471003)
RGD
Ensembl
PMID:27471003 GO_REF:0000107, MGI:MGI:6095248 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
positive regulation of very-low-density lipoprotein particle remodeling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa5 apolipoprotein A5 ISO
IEA
(PMID:18635818)
GO_REF:0000107
RGD
Ensembl
PMID:18635818 GO_REF:0000107 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    multicellular organismal process 9046
      plasma lipoprotein particle organization 40
        plasma lipoprotein particle remodeling 27
          triglyceride-rich lipoprotein particle remodeling 10
            very-low-density lipoprotein particle remodeling 10
              negative regulation of very-low-density lipoprotein particle remodeling 4
              positive regulation of very-low-density lipoprotein particle remodeling 1
              regulation of very-low-density lipoprotein particle remodeling + 5
Path 2
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          protein-containing complex subunit organization 1813
            protein-containing complex remodeling 29
              protein-lipid complex remodeling 27
                plasma lipoprotein particle remodeling 27
                  triglyceride-rich lipoprotein particle remodeling 10
                    very-low-density lipoprotein particle remodeling 10
                      negative regulation of very-low-density lipoprotein particle remodeling 4
                      positive regulation of very-low-density lipoprotein particle remodeling 1
                      regulation of very-low-density lipoprotein particle remodeling + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.