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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpi centromere protein I JBrowse link X 105,147,045 105,198,798 RGD:1600115
G Cenpo centromere protein O JBrowse link 6 28,648,804 28,663,527 RGD:1600115
G Cenpv centromere protein V JBrowse link 10 48,846,513 48,861,893 RGD:1624291
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpp centromere protein P JBrowse link 17 15,429,526 15,603,197 RGD:1600115
G Hjurp Holliday junction recognition protein JBrowse link 9 95,347,739 95,362,228 RGD:1624291
G Itgb3bp integrin subunit beta 3 binding protein JBrowse link 5 118,476,410 118,541,928 RGD:1600115
G Mis18a MIS18 kinetochore protein A JBrowse link 11 30,880,231 30,893,262 RGD:1624291
RGD:13792537
G Nasp nuclear autoantigenic sperm protein JBrowse link 5 135,446,485 135,472,113 RGD:13792537
G Oip5 Opa interacting protein 5 JBrowse link 3 111,413,662 111,422,320 RGD:13792537
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07030926.1 RGD:1600115
G Cenpa centromere protein A JBrowse link 6 27,072,259 27,080,863 RGD:1624291
G Cenpc centromere protein C JBrowse link 14 23,611,909 23,670,314 RGD:1624291
RGD:13792537
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Cenph centromere protein H JBrowse link 2 30,766,637 30,780,123 RGD:1600115
G Cenpk centromere protein K JBrowse link 2 34,312,766 34,373,945 RGD:1600115
G Cenpn centromere protein N JBrowse link 19 49,457,461 49,479,989 RGD:1600115
G Cenpt centromere protein T JBrowse link 19 37,813,284 37,819,782 RGD:1624291
RGD:1600115
G Cenpw centromere protein W JBrowse link 1 29,915,443 29,920,598 RGD:1624291
RGD:13792537
RGD:1600115
G Mis12 MIS12 kinetochore complex component JBrowse link 10 57,653,685 57,661,833 RGD:1624291
RGD:1600115
RGD:13792537
G Pogz pogo transposable element derived with ZNF domain JBrowse link 2 195,995,322 196,041,500 RGD:1624291
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpv centromere protein V JBrowse link 10 48,846,513 48,861,893 RGD:1624291
RGD:13792537
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G H3f3a H3 histone family member 3A JBrowse link 13 99,091,246 99,102,828 RGD:1624291
G H3f3b H3 histone family member 3B JBrowse link 10 104,573,666 104,575,890 RGD:1624291
G Hells helicase, lymphoid specific JBrowse link 1 257,901,856 257,953,889 RGD:1624291
RGD:13792537
G LOC100911660 lymphocyte-specific helicase-like JBrowse link 1 257,614,688 257,660,184 RGD:13792537
G Znfx1 zinc finger, NFX1-type containing 1 JBrowse link 3 163,787,101 163,847,671 RGD:13792537
protein localization to kinetochore involved in kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpt centromere protein T JBrowse link 19 37,813,284 37,819,782 RGD:13792537
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H3f3b H3 histone family member 3B JBrowse link 10 104,573,666 104,575,890 RGD:1624291
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf4 ring finger protein 4 JBrowse link 14 81,658,400 81,679,756 RGD:1600115
RGD:1624291
G Senp6 SUMO specific peptidase 6 JBrowse link 8 87,486,050 87,568,088 RGD:1624291
RGD:13792537
G Trappc12 trafficking protein particle complex 12 JBrowse link 6 47,954,822 48,020,280 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    cellular process 18452
      cellular component organization or biogenesis 6666
        cellular component organization 6426
          organelle organization 4013
            chromosome organization 1231
              centromere complex assembly 29
                CENP-A containing nucleosome assembly + 6
                kinetochore assembly + 14
                pericentric heterochromatin assembly + 7
                regulation of centromere complex assembly + 4
Path 2
Term Annotations click to browse term
  biological_process 19678
    cellular process 18452
      cellular component organization or biogenesis 6666
        cellular component biogenesis 3235
          cellular component assembly 2942
            protein-containing complex assembly 1588
              cellular protein-containing complex assembly 1118
                protein-DNA complex assembly 202
                  centromere complex assembly 29
                    CENP-A containing nucleosome assembly + 6
                    kinetochore assembly + 14
                    pericentric heterochromatin assembly + 7
                    regulation of centromere complex assembly + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.