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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPV centromere protein V JBrowse link 17 35,247,664 35,258,656 RGD:9068941
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HJURP Holliday junction recognition protein JBrowse link 2B 121,076,314 121,096,783 RGD:9068941
G MIS18A MIS18 kinetochore protein A JBrowse link 21 18,635,735 18,646,611 RGD:9068941
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPA centromere protein A JBrowse link 2A 26,785,301 26,800,178 RGD:9068941
G CENPC centromere protein C JBrowse link 4 56,503,353 56,615,246 RGD:9068941
G CENPE centromere protein E JBrowse link 4 95,562,005 95,654,397 RGD:9068941
G CENPT centromere protein T JBrowse link 16 48,169,892 48,177,559 RGD:9068941
G CENPW centromere protein W JBrowse link 6 124,125,492 124,272,450 RGD:9068941
G MIS12 MIS12 kinetochore complex component JBrowse link 17 5,534,305 5,538,736 RGD:9068941
G POGZ pogo transposable element derived with ZNF domain JBrowse link 1 126,761,777 126,818,262 RGD:9068941
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPV centromere protein V JBrowse link 17 35,247,664 35,258,656 RGD:9068941
G DICER1 dicer 1, ribonuclease III JBrowse link 14 75,709,029 75,780,779 RGD:9068941
G HELLS helicase, lymphoid specific JBrowse link 10 91,282,330 91,344,156 RGD:9068941
G LOC100970414 histone H3.3A JBrowse link 1 201,523,670 201,533,005 RGD:9068941
G LOC100988671 histone H3.3A JBrowse link 17 69,728,165 69,730,519 RGD:9068941
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100988671 histone H3.3A JBrowse link 17 69,728,165 69,730,519 RGD:9068941
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF4 ring finger protein 4 JBrowse link 4 2,614,918 2,661,785 RGD:9068941
G SENP6 SUMO specific peptidase 6 JBrowse link 6 73,445,608 73,562,018 RGD:9068941
G TRAPPC12 trafficking protein particle complex 12 JBrowse link 2A 3,388,191 3,490,496 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12490
    cellular process 11598
      cellular component organization or biogenesis 4957
        cellular component organization 4877
          organelle organization 3003
            chromosome organization 874
              centromere complex assembly 17
                CENP-A containing nucleosome assembly + 2
                kinetochore assembly + 10
                pericentric heterochromatin assembly + 5
                regulation of centromere complex assembly + 4
Path 2
Term Annotations click to browse term
  biological_process 12490
    cellular process 11598
      cellular component organization or biogenesis 4957
        cellular component biogenesis 2345
          cellular component assembly 2231
            protein-containing complex assembly 1078
              cellular protein-containing complex assembly 694
                protein-DNA complex assembly 85
                  centromere complex assembly 17
                    CENP-A containing nucleosome assembly + 2
                    kinetochore assembly + 10
                    pericentric heterochromatin assembly + 5
                    regulation of centromere complex assembly + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.