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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpv centromere protein V JBrowse link NW_004955467 1,657,765 1,669,758 RGD:9068941
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hjurp Holliday junction recognition protein JBrowse link NW_004955453 2,323,018 2,335,090 RGD:9068941
G Mis18a MIS18 kinetochore protein A JBrowse link NW_004955407 31,799,537 31,813,897 RGD:9068941
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpa centromere protein A JBrowse link NW_004955469 8,799,312 8,819,637 RGD:9068941
G Cenpc centromere protein C JBrowse link NW_004955447 5,345,617 5,406,889 RGD:9068941
G Cenpe centromere protein E JBrowse link NW_004955496 5,468,759 5,514,915 RGD:9068941
G Cenpt centromere protein T JBrowse link NW_004955484 8,862,221 8,867,881 RGD:9068941
G Cenpw centromere protein W JBrowse link NW_004955436 7,557,595 7,563,238 RGD:9068941
G Mis12 MIS12 kinetochore complex component JBrowse link NW_004955467 10,837,570 10,842,131 RGD:9068941
G Pogz pogo transposable element derived with ZNF domain JBrowse link NW_004955589 920,729 975,242 RGD:9068941
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpv centromere protein V JBrowse link NW_004955467 1,657,765 1,669,758 RGD:9068941
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004955438 17,374,899 17,431,599 RGD:9068941
G H3f3a H3 histone, family 3A JBrowse link NW_004955489 269,900 278,398 RGD:9068941
G H3f3b H3 histone, family 3B JBrowse link NW_004955506 6,475,336 6,478,781 RGD:9068941
G Hells helicase, lymphoid specific JBrowse link NW_004955507 995,389 1,034,852 RGD:9068941
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H3f3b H3 histone, family 3B JBrowse link NW_004955506 6,475,336 6,478,781 RGD:9068941
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf4 ring finger protein 4 JBrowse link NW_004955514 1,501,943 1,525,689 RGD:9068941
G Senp6 SUMO specific peptidase 6 JBrowse link NW_004955502 4,082,217 4,180,696 RGD:9068941
G Trappc12 trafficking protein particle complex 12 JBrowse link NW_004955487 3,824,872 3,863,859 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11825
    cellular process 11033
      cellular component organization or biogenesis 4817
        cellular component organization 4737
          organelle organization 2919
            chromosome organization 841
              centromere complex assembly 17
                CENP-A containing nucleosome assembly + 2
                kinetochore assembly + 10
                pericentric heterochromatin assembly + 5
                regulation of centromere complex assembly + 4
Path 2
Term Annotations click to browse term
  biological_process 11825
    cellular process 11033
      cellular component organization or biogenesis 4817
        cellular component biogenesis 2280
          cellular component assembly 2166
            protein-containing complex assembly 1032
              cellular protein-containing complex assembly 660
                protein-DNA complex assembly 76
                  centromere complex assembly 17
                    CENP-A containing nucleosome assembly + 2
                    kinetochore assembly + 10
                    pericentric heterochromatin assembly + 5
                    regulation of centromere complex assembly + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.