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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPI centromere protein I JBrowse link X 75,035,147 75,112,991 RGD:13508589
G CENPO centromere protein O JBrowse link 17 19,132,721 19,154,431 RGD:13508589
G CENPV centromere protein V JBrowse link 5 39,568,115 39,582,900 RGD:9068941
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPP centromere protein P JBrowse link 1 98,801,384 99,019,371 RGD:13508589
G HJURP Holliday junction recognition protein JBrowse link 25 45,215,165 45,230,603 RGD:13508589
G ITGB3BP integrin subunit beta 3 binding protein JBrowse link 5 46,645,858 46,716,170 RGD:13508589
G MIS18A MIS18 kinetochore protein A JBrowse link 31 27,025,657 27,039,001 RGD:13508589
G NASP nuclear autoantigenic sperm protein JBrowse link 15 14,742,008 14,782,186 RGD:13508589
G OIP5 Opa interacting protein 5 JBrowse link 30 8,377,407 8,396,222 RGD:13508589
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPA centromere protein A JBrowse link 17 20,808,320 20,833,747 RGD:13508589
G CENPC centromere protein C JBrowse link 13 58,013,218 58,091,347 RGD:13508589
G CENPE centromere protein E JBrowse link 32 24,447,373 24,530,407 RGD:13508589
G CENPH centromere protein H JBrowse link 2 54,267,782 54,299,083 RGD:13508589
G CENPK centromere protein K JBrowse link 2 51,262,475 51,300,016 RGD:13508589
G CENPN centromere protein N JBrowse link 5 70,798,322 70,820,927 RGD:13508589
G CENPT centromere protein T JBrowse link 5 81,641,261 81,647,047 RGD:13508589
G CENPW centromere protein W JBrowse link 1 65,171,785 65,178,357 RGD:13508589
G LOC102154136 protein MIS12 homolog JBrowse link 5 42,965,045 42,966,881 RGD:13508589
G MIS12 MIS12 kinetochore complex component JBrowse link 5 31,314,067 31,319,392 RGD:13508589
G POGZ pogo transposable element derived with ZNF domain JBrowse link 17 60,464,609 60,511,735 RGD:13508589
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPV centromere protein V JBrowse link 5 39,568,115 39,582,900 RGD:9068941
G DICER1 dicer 1, ribonuclease III JBrowse link 8 63,970,245 64,029,438 RGD:9068941
G H3-3A H3.3 histone A JBrowse link 7 38,797,168 38,805,417 RGD:13508589
G H3-3B H3.3 histone B JBrowse link 9 4,805,655 4,808,076 RGD:13508589
G HELLS helicase, lymphoid specific JBrowse link 28 8,660,866 8,705,570 RGD:13508589
G ZNFX1 zinc finger NFX1-type containing 1 JBrowse link 24 35,932,037 35,954,170 RGD:13508589
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H3-3A H3.3 histone A JBrowse link 7 38,797,168 38,805,417 RGD:13508589
G H3-3B H3.3 histone B JBrowse link 9 4,805,655 4,808,076 RGD:13508589
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF4 ring finger protein 4 JBrowse link 3 61,721,752 61,759,797 RGD:13508589
G SENP6 SUMO specific peptidase 6 JBrowse link 12 37,218,707 37,336,244 RGD:13508589
G TRAPPC12 trafficking protein particle complex 12 JBrowse link 17 1,988,952 2,072,854 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16042
    cellular process 15297
      cellular component organization or biogenesis 5950
        cellular component organization 5787
          organelle organization 3647
            chromosome organization 1083
              centromere complex assembly 28
                CENP-A containing nucleosome assembly + 6
                kinetochore assembly + 14
                pericentric heterochromatin assembly + 6
                regulation of centromere complex assembly + 5
Path 2
Term Annotations click to browse term
  biological_process 16042
    cellular process 15297
      cellular component organization or biogenesis 5950
        cellular component biogenesis 2905
          cellular component assembly 2692
            protein-containing complex assembly 1414
              cellular protein-containing complex assembly 971
                protein-DNA complex assembly 165
                  centromere complex assembly 28
                    CENP-A containing nucleosome assembly + 6
                    kinetochore assembly + 14
                    pericentric heterochromatin assembly + 6
                    regulation of centromere complex assembly + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.