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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPI centromere protein I JBrowse link X 101,098,159 101,181,847 RGD:2290271
G CENPV centromere protein V JBrowse link 17 16,342,537 16,353,469 RGD:2290271
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPA centromere protein A JBrowse link 2 26,786,015 26,794,589 RGD:2290271
G CENPC centromere protein C JBrowse link 4 67,468,762 67,545,503 RGD:2290271
G CENPH centromere protein H JBrowse link 5 69,189,583 69,210,357 RGD:2290271
G CENPI centromere protein I JBrowse link X 101,098,159 101,181,847 RGD:2290271
G CENPK centromere protein K JBrowse link 5 65,488,919 65,563,194 RGD:2290271
G CENPL centromere protein L JBrowse link 1 173,799,550 173,824,639 RGD:2290271
G CENPM centromere protein M JBrowse link 22 41,927,747 41,947,164 RGD:2290271
G CENPN centromere protein N JBrowse link 16 81,006,498 81,033,107 RGD:2290271
G CENPO centromere protein O JBrowse link 2 24,793,115 24,822,376 RGD:2290271
G CENPP centromere protein P JBrowse link 9 92,325,457 92,620,529 RGD:2290271
G CENPQ centromere protein Q JBrowse link 6 49,463,327 49,493,107 RGD:2290271
G CENPS centromere protein S JBrowse link 1 10,430,433 10,442,808 RGD:2290271
G CENPS-CORT CENPS-CORT readthrough JBrowse link 1 10,430,433 10,452,153 RGD:2290271
G CENPT centromere protein T JBrowse link 16 67,828,157 67,847,693 RGD:2290271
G CENPU centromere protein U JBrowse link 4 184,694,085 184,734,096 RGD:2290271
G CENPW centromere protein W JBrowse link 6 126,339,696 126,483,320 RGD:2290271
G CENPX centromere protein X JBrowse link 17 82,018,703 82,022,930 RGD:2290271
G H4-16 H4 histone 16 JBrowse link 12 14,770,720 14,771,131 RGD:2290271
G H4C1 H4 clustered histone 1 JBrowse link 6 26,021,649 26,022,050 RGD:2290271
G H4C11 H4 clustered histone 11 JBrowse link 6 27,824,092 27,824,480 RGD:2290271
G H4C12 H4 clustered histone 12 JBrowse link 6 27,831,174 27,831,560 RGD:2290271
G H4C13 H4 clustered histone 13 JBrowse link 6 27,873,148 27,873,534 RGD:2290271
G H4C14 H4 clustered histone 14 JBrowse link 1 149,832,657 149,833,052 RGD:2290271
G H4C15 H4 clustered histone 15 JBrowse link 1 149,853,262 149,861,159 RGD:2290271
G H4C2 H4 clustered histone 2 JBrowse link 6 26,026,896 26,027,283 RGD:2290271
G H4C3 H4 clustered histone 3 JBrowse link 6 26,103,933 26,104,337 RGD:2290271
G H4C4 H4 clustered histone 4 JBrowse link 6 26,188,710 26,189,112 RGD:2290271
G H4C5 H4 clustered histone 5 JBrowse link 6 26,204,610 26,205,021 RGD:2290271
G H4C6 H4 clustered histone 6 JBrowse link 6 26,240,393 26,240,793 RGD:2290271
G H4C8 H4 clustered histone 8 JBrowse link 6 26,285,126 26,285,534 RGD:2290271
G H4C9 H4 clustered histone 9 JBrowse link 6 27,139,282 27,139,678 RGD:2290271
G HJURP Holliday junction recognition protein JBrowse link 2 233,836,701 233,854,566 RGD:2290271
G ITGB3BP integrin subunit beta 3 binding protein JBrowse link 1 63,440,770 63,529,395 RGD:2290271
G KNL1 kinetochore scaffold 1 JBrowse link 15 40,594,012 40,664,342 RGD:2290271
G MIS18A MIS18 kinetochore protein A JBrowse link 21 32,154,682 32,283,954 RGD:2290271
G MIS18BP1 MIS18 binding protein 1 JBrowse link 14 45,203,190 45,257,190 RGD:2290271
G NASP nuclear autoantigenic sperm protein JBrowse link 1 45,583,988 45,618,906 RGD:2290271
G NPM1 nucleophosmin 1 JBrowse link 5 171,387,116 171,410,900 RGD:2290271
G OIP5 Opa interacting protein 5 JBrowse link 15 41,309,268 41,332,621 RGD:2290271
G RBBP4 RB binding protein 4, chromatin remodeling factor JBrowse link 1 32,651,208 32,686,211 RGD:2290271
G RBBP7 RB binding protein 7, chromatin remodeling factor JBrowse link X 16,844,341 16,870,362 RGD:2290271
G RSF1 remodeling and spacing factor 1 JBrowse link 11 77,660,009 77,872,232 RGD:2290271
G RUVBL1 RuvB like AAA ATPase 1 JBrowse link 3 128,064,611 128,153,914 RGD:2290271
G SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 JBrowse link 4 143,513,501 143,557,486 RGD:2290271
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPA centromere protein A JBrowse link 2 26,786,015 26,794,589 RGD:2290271
G CENPC centromere protein C JBrowse link 4 67,468,762 67,545,503 RGD:2290271
G CENPE centromere protein E JBrowse link 4 103,105,811 103,198,408 RGD:2290271
G CENPF centromere protein F JBrowse link 1 214,603,195 214,664,571 RGD:2290271
G CENPH centromere protein H JBrowse link 5 69,189,583 69,210,357 RGD:2290271
G CENPK centromere protein K JBrowse link 5 65,488,919 65,563,194 RGD:2290271
G CENPN centromere protein N JBrowse link 16 81,006,498 81,033,107 RGD:2290271
G CENPS centromere protein S JBrowse link 1 10,430,433 10,442,808 RGD:2290271
G CENPS-CORT CENPS-CORT readthrough JBrowse link 1 10,430,433 10,452,153 RGD:2290271
G CENPT centromere protein T JBrowse link 16 67,828,157 67,847,693 RGD:2290271
G CENPW centromere protein W JBrowse link 6 126,339,696 126,483,320 RGD:2290271
G CENPX centromere protein X JBrowse link 17 82,018,703 82,022,930 RGD:2290271
G MIS12 MIS12 kinetochore complex component JBrowse link 17 5,486,374 5,490,814 RGD:2290271
G POGZ pogo transposable element derived with ZNF domain JBrowse link 1 151,402,724 151,459,494 RGD:2290271
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPV centromere protein V JBrowse link 17 16,342,537 16,353,469 RGD:2290271
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:9068941
G H3-3A H3.3 histone A JBrowse link 1 226,061,831 226,072,019 RGD:2290271
G H3-3B H3.3 histone B JBrowse link 17 75,776,434 75,779,779 RGD:2290271
G HELLS helicase, lymphoid specific JBrowse link 10 94,545,767 94,613,905 RGD:2290271
G ZNFX1 zinc finger NFX1-type containing 1 JBrowse link 20 49,245,900 49,278,057 RGD:2290271
protein localization to kinetochore involved in kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPT centromere protein T JBrowse link 16 67,828,157 67,847,693 RGD:2290271
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H3-3A H3.3 histone A JBrowse link 1 226,061,831 226,072,019 RGD:2290271
G H3-3B H3.3 histone B JBrowse link 17 75,776,434 75,779,779 RGD:2290271
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,303,751 48,481,890 RGD:2290271
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF4 ring finger protein 4 JBrowse link 4 2,469,106 2,515,859 RGD:2290271
G SENP6 SUMO specific peptidase 6 JBrowse link 6 75,601,509 75,718,281 RGD:2290271
G TRAPPC12 trafficking protein particle complex 12 JBrowse link 2 3,379,245 3,479,571 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18536
    cellular process 17546
      cellular component organization or biogenesis 7082
        cellular component organization 6891
          organelle organization 4291
            chromosome organization 1326
              centromere complex assembly 58
                CENP-A containing nucleosome assembly + 44
                kinetochore assembly + 17
                pericentric heterochromatin assembly + 6
                regulation of centromere complex assembly + 6
Path 2
Term Annotations click to browse term
  biological_process 18536
    cellular process 17546
      cellular component organization or biogenesis 7082
        cellular component biogenesis 3460
          cellular component assembly 3209
            protein-containing complex assembly 1780
              cellular protein-containing complex assembly 1173
                protein-DNA complex assembly 263
                  centromere complex assembly 58
                    CENP-A containing nucleosome assembly + 44
                    kinetochore assembly + 17
                    pericentric heterochromatin assembly + 6
                    regulation of centromere complex assembly + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.