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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpi centromere protein I JBrowse link X 134,308,084 134,363,104 RGD:2290270
G Cenpo centromere protein O JBrowse link 12 4,195,398 4,234,255 RGD:2290270
G Cenpv centromere protein V JBrowse link 11 62,524,944 62,539,869 RGD:2290270
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpp centromere protein P JBrowse link 13 49,464,025 49,652,950 RGD:2290270
G Hjurp Holliday junction recognition protein JBrowse link 1 88,258,856 88,277,644 RGD:2290270
G Itgb3bp integrin beta 3 binding protein (beta3-endonexin) JBrowse link 4 99,767,406 99,829,215 RGD:2290270
G Mis18a MIS18 kinetochore protein A JBrowse link 16 90,719,312 90,727,371 RGD:2290270
G Nasp nuclear autoantigenic sperm protein (histone-binding) JBrowse link 4 116,601,052 116,628,676 RGD:2290270
G Oip5 Opa interacting protein 5 JBrowse link 2 119,609,532 119,618,505 RGD:2290270
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpa centromere protein A JBrowse link 5 30,666,877 30,674,837 RGD:2290270
G Cenpc1 centromere protein C1 JBrowse link 5 86,012,018 86,065,962 RGD:2290270
G Cenpe centromere protein E JBrowse link 3 135,212,563 135,273,540 RGD:2290270
G Cenph centromere protein H JBrowse link 13 100,759,674 100,775,903 RGD:2290270
G Cenpk centromere protein K JBrowse link 13 104,228,611 104,249,622 RGD:2290270
G Cenpn centromere protein N JBrowse link 8 116,921,716 116,941,504 RGD:2290270
G Cenps centromere protein S JBrowse link 4 149,128,349 149,137,600 RGD:2290270
G Cenpt centromere protein T JBrowse link 8 105,844,669 105,855,086 RGD:2290270
G Cenpw centromere protein W JBrowse link 10 30,196,009 30,200,603 RGD:2290270
G Cenpx centromere protein X JBrowse link 11 120,710,941 120,713,895 RGD:2290270
G Dlgap5 DLG associated protein 5 JBrowse link 14 47,387,779 47,418,407 RGD:2290270
G Mis12 MIS12 kinetochore complex component JBrowse link 11 71,019,568 71,027,371 RGD:2290270
G Pogz pogo transposable element with ZNF domain JBrowse link 3 94,822,989 94,883,577 RGD:2290270
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpv centromere protein V JBrowse link 11 62,524,944 62,539,869 RGD:2290270
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
G H3f3a H3.3 histone A JBrowse link 1 180,802,560 180,813,605 RGD:2290270
G H3f3b H3.3 histone B JBrowse link 11 116,021,961 116,026,039 RGD:2290270
G Hells helicase, lymphoid specific JBrowse link 19 38,930,262 38,970,470 RGD:2290270
protein localization to kinetochore involved in kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpt centromere protein T JBrowse link 8 105,844,669 105,855,086 RGD:2290270
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H3f3b H3.3 histone B JBrowse link 11 116,021,961 116,026,039 RGD:2290270
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf4 ring finger protein 4 JBrowse link 5 34,336,250 34,353,445 RGD:2290270
G Senp6 SUMO/sentrin specific peptidase 6 JBrowse link 9 80,066,575 80,144,782 RGD:2290270
G Trappc12 trafficking protein particle complex 12 JBrowse link 12 28,690,620 28,750,485 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23311
    cellular process 17299
      cellular component organization or biogenesis 6355
        cellular component organization 6167
          organelle organization 3803
            chromosome organization 1169
              centromere complex assembly 29
                CENP-A containing nucleosome assembly + 6
                kinetochore assembly + 16
                pericentric heterochromatin assembly + 5
                regulation of centromere complex assembly + 4
Path 2
Term Annotations click to browse term
  biological_process 23311
    cellular process 17299
      cellular component organization or biogenesis 6355
        cellular component biogenesis 3001
          cellular component assembly 2759
            protein-containing complex assembly 1438
              cellular protein-containing complex assembly 981
                protein-DNA complex assembly 178
                  centromere complex assembly 29
                    CENP-A containing nucleosome assembly + 6
                    kinetochore assembly + 16
                    pericentric heterochromatin assembly + 5
                    regulation of centromere complex assembly + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.