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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPI centromere protein I JBrowse link X 82,776,375 82,826,651 RGD:14298760
G CENPV centromere protein V JBrowse link 12 59,200,041 59,215,941 RGD:9068941
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPP centromere protein P JBrowse link 3 42,053,074 42,309,745 RGD:14298760
G HJURP Holliday junction recognition protein JBrowse link 15 134,106,561 134,123,163 RGD:14298760
G MIS18A MIS18 kinetochore protein A JBrowse link 13 195,912,044 195,928,309 RGD:14298760
G NASP nuclear autoantigenic sperm protein JBrowse link 6 165,773,964 165,804,978 RGD:14298760
G OIP5 Opa interacting protein 5 JBrowse link 1 130,036,478 130,054,058 RGD:14298760
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APITD1 apoptosis-inducing, TAF9-like domain 1 JBrowse link 6 70,700,802 70,711,719 RGD:14298760
G CENPA centromere protein A JBrowse link 3 112,263,912 112,272,638 RGD:14298760
G CENPC centromere protein C JBrowse link 8 65,237,825 65,315,788 RGD:14298760
G CENPE centromere protein E JBrowse link 8 117,888,968 117,965,325 RGD:14298760
G CENPH centromere protein H JBrowse link 16 47,353,319 47,378,746 RGD:14298760
G CENPK centromere protein K JBrowse link 16 44,008,673 44,080,565 RGD:14298760
G CENPN centromere protein N JBrowse link 6 7,227,981 7,254,927 RGD:14298760
G CENPT centromere protein T JBrowse link 6 28,450,568 28,456,620 RGD:14298760
G CENPW centromere protein W JBrowse link 1 36,405,693 36,695,989 RGD:14298760
G CENPX centromere protein X JBrowse link 12 991,618 994,849 RGD:14298760
G MIS12 MIS12 kinetochore complex component JBrowse link 12 51,505,376 51,508,337 RGD:14298760
G POGZ pogo transposable element derived with ZNF domain JBrowse link 4 97,776,579 97,833,287 RGD:14298760
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPV centromere protein V JBrowse link 12 59,200,041 59,215,941 RGD:14298760
G DICER1 dicer 1, ribonuclease III JBrowse link 7 116,361,630 116,436,471 RGD:9068941
G H3-3A H3 histone, family 3A JBrowse link 10 13,939,938 13,947,976 RGD:14298760
G HELLS helicase, lymphoid specific JBrowse link 14 105,923,727 105,967,003 RGD:14298760
G LOC100521680 histone H3.3 JBrowse link 12 5,632,326 5,634,977 RGD:14298760
G ZNFX1 zinc finger NFX1-type containing 1 JBrowse link 17 50,925,789 50,958,722 RGD:14298760
protein localization to kinetochore involved in kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPT centromere protein T JBrowse link 6 28,450,568 28,456,620 RGD:14298760
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H3-3A H3 histone, family 3A JBrowse link 10 13,939,938 13,947,976 RGD:14298760
G LOC100521680 histone H3.3 JBrowse link 12 5,632,326 5,634,977 RGD:14298760
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RNF4 ring finger protein 4 JBrowse link 8 1,353,532 1,380,637 RGD:14298760
G SENP6 SUMO specific peptidase 6 JBrowse link 1 90,166,997 90,299,981 RGD:14298760
G TRAPPC12 trafficking protein particle complex 12 JBrowse link 3 131,307,185 131,357,996 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16412
    cellular process 15624
      cellular component organization or biogenesis 5902
        cellular component organization 5740
          organelle organization 3604
            chromosome organization 1067
              centromere complex assembly 27
                CENP-A containing nucleosome assembly + 5
                kinetochore assembly + 15
                pericentric heterochromatin assembly + 6
                regulation of centromere complex assembly + 5
Path 2
Term Annotations click to browse term
  biological_process 16412
    cellular process 15624
      cellular component organization or biogenesis 5902
        cellular component biogenesis 2884
          cellular component assembly 2674
            protein-containing complex assembly 1396
              cellular protein-containing complex assembly 944
                protein-DNA complex assembly 155
                  centromere complex assembly 27
                    CENP-A containing nucleosome assembly + 5
                    kinetochore assembly + 15
                    pericentric heterochromatin assembly + 6
                    regulation of centromere complex assembly + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.