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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpv centromere protein V JBrowse link NW_004936821 267,137 276,969 RGD:9068941
CENP-A containing nucleosome assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hjurp Holliday junction recognition protein JBrowse link NW_004936525 3,528,379 3,544,088 RGD:9068941
G Mis18a MIS18 kinetochore protein A JBrowse link NW_004936500 9,822,366 9,832,732 RGD:9068941
kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpa centromere protein A JBrowse link NW_004936493 5,715,274 5,720,816 RGD:9068941
G Cenpc centromere protein C JBrowse link NW_004936582 920,852 978,167 RGD:9068941
G Cenpe centromere protein E JBrowse link NW_004936520 188,601 265,904 RGD:9068941
G Cenpt centromere protein T JBrowse link NW_004936475 18,198,725 18,204,257 RGD:9068941
G Cenpw centromere protein W JBrowse link NW_004936639 3,173,832 3,184,439 RGD:9068941
G Mis12 MIS12 kinetochore complex component JBrowse link NW_004936677 2,323,540 2,328,689 RGD:9068941
G Pogz pogo transposable element derived with ZNF domain JBrowse link NW_004936580 1,613,425 1,650,849 RGD:9068941
pericentric heterochromatin assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpv centromere protein V JBrowse link NW_004936821 267,137 276,969 RGD:9068941
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004936846 528,768 584,599 RGD:9068941
G Hells helicase, lymphoid specific JBrowse link NW_004936601 626,354 662,477 RGD:9068941
G LOC101963041 histone H3.3 JBrowse link NW_004936526 2,835,002 2,842,328 RGD:9068941
G LOC101963257 histone H3.3 JBrowse link NW_004936594 959,493 961,703 RGD:9068941
regulation of centromere complex assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC101963257 histone H3.3 JBrowse link NW_004936594 959,493 961,703 RGD:9068941
regulation of kinetochore assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf4 ring finger protein 4 JBrowse link NW_004936477 21,025,040 21,055,821 RGD:9068941
G Senp6 SUMO specific peptidase 6 JBrowse link NW_004936788 995,260 1,104,561 RGD:9068941
G Trappc12 trafficking protein particle complex 12 JBrowse link NW_004936532 1,613,181 1,674,556 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11931
    cellular process 11113
      cellular component organization or biogenesis 4869
        cellular component organization 4791
          organelle organization 2956
            chromosome organization 861
              centromere complex assembly 17
                CENP-A containing nucleosome assembly + 2
                kinetochore assembly + 10
                pericentric heterochromatin assembly + 5
                regulation of centromere complex assembly + 4
Path 2
Term Annotations click to browse term
  biological_process 11931
    cellular process 11113
      cellular component organization or biogenesis 4869
        cellular component biogenesis 2309
          cellular component assembly 2196
            protein-containing complex assembly 1052
              cellular protein-containing complex assembly 678
                protein-DNA complex assembly 82
                  centromere complex assembly 17
                    CENP-A containing nucleosome assembly + 2
                    kinetochore assembly + 10
                    pericentric heterochromatin assembly + 5
                    regulation of centromere complex assembly + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.