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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to heat
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Accession:GO:0034605 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
Synonyms:exact_synonym: cellular response to heat stress


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cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ano1 anoctamin 1 JBrowse link 1 217,754,349 217,902,540 RGD:1624291
RGD:1600115
G Arpp21 cAMP regulated phosphoprotein 21 JBrowse link 8 120,323,895 120,492,790 RGD:1624291
RGD:1600115
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:10047286
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:1624291
RGD:1600115
G Bag3 Bcl2-associated athanogene 3 JBrowse link 1 199,941,258 199,965,191 RGD:1624291
RGD:1600115
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8547793
G Cetn1 centrin 1 JBrowse link 18 785,972 786,674 RGD:1624291
RGD:1600115
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11567213
G Clpb ClpB homolog, mitochondrial AAA ATPase chaperonin JBrowse link 1 166,739,372 166,866,095 RGD:1600115
RGD:1624291
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:2311382
G Daxx death-domain associated protein JBrowse link 20 5,480,103 5,485,962 RGD:1624291
RGD:1600115
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 6 102,048,372 102,073,041 RGD:10395354
RGD:10395357
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:1624291
RGD:1600115
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:2306446
G Hikeshi heat shock protein nuclear import factor JBrowse link 1 154,147,098 154,170,429 RGD:1600115
RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1624291
RGD:1600115
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:10402942
RGD:13792537
RGD:1624291
G Hsf2 heat shock transcription factor 2 JBrowse link 20 38,935,820 38,963,444 RGD:13792537
G Hsf4 heat shock transcription factor 4 JBrowse link 19 37,225,800 37,232,048 RGD:13792537
G Hsf5 heat shock transcription factor 5 JBrowse link 10 74,909,621 74,954,128 RGD:13792537
G Hsfy2 heat shock transcription factor, Y linked 2 JBrowse link 9 63,289,937 63,291,350 RGD:13792537
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:13792537
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:13792537
G Hspa13 heat shock protein family A (Hsp70) member 13 JBrowse link 11 14,146,515 14,160,697 RGD:13792537
G Hspa14 heat shock protein family A (Hsp70) member 14 JBrowse link 17 78,735,630 78,756,412 RGD:13792537
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
RGD:13792537
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
RGD:13792537
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:13792537
G Hspa2 heat shock protein family A (Hsp70) member 2 JBrowse link 6 99,433,575 99,436,288 RGD:13792537
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:13792537
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:10059375
RGD:13792537
G Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:13792537
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:12910540
G Htra2 HtrA serine peptidase 2 JBrowse link 4 113,883,671 113,886,833 RGD:1624291
RGD:1600115
G Ier5 immediate early response 5 JBrowse link 13 72,742,210 72,744,302 RGD:1624291
RGD:1600115
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:1600115
RGD:1624291
G Irak1 interleukin-1 receptor-associated kinase 1 JBrowse link X 156,716,469 156,726,367 RGD:7495799
G LOC103692716 heat shock protein HSP 90-alpha JBrowse link 6 135,044,833 135,050,417 RGD:13792537
G LOC108348108 heat shock 70 kDa protein 1A JBrowse link 20 2,699,707 2,701,856 RGD:13792537
G LOC680121 similar to heat shock protein 8 JBrowse link 11 13,499,168 13,501,271 RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:2303719
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:2317714
G Myof myoferlin JBrowse link 1 256,585,410 256,734,727 RGD:1624291
RGD:1600115
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:5132625
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
RGD:1600115
G Pdcl3 phosducin-like 3 JBrowse link 9 45,672,257 45,680,728 RGD:14695071
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1624291
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
RGD:1600115
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11567213
G Rasa3 RAS p21 protein activator 3 JBrowse link 16 81,320,090 81,434,239 RGD:10047323
G Scara5 scavenger receptor class A, member 5 JBrowse link 15 49,069,142 49,177,159 RGD:1624291
RGD:1600115
G Slc52a3 solute carrier family 52 member 3 JBrowse link 3 147,503,266 147,517,935 RGD:1624291
RGD:1600115
G Slu7 SLU7 homolog, splicing factor JBrowse link 10 29,029,556 29,044,919 RGD:1624291
RGD:1600115
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 JBrowse link 4 177,065,266 177,195,942 RGD:1624291
RGD:1600115
G Stac SH3 and cysteine rich domain JBrowse link 8 119,820,664 119,941,867 RGD:1624291
RGD:1600115
G Stub1 STIP1 homology and U-box containing protein 1 JBrowse link 10 15,197,754 15,200,035 RGD:13507303
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:1624291
RGD:1600115
G Tcim transcriptional and immune response regulator JBrowse link 16 72,401,526 72,403,180 RGD:1624291
G Tfec transcription factor EC JBrowse link 4 44,063,533 44,136,815 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8547793
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1624291
RGD:1600115
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 JBrowse link 5 3,783,247 3,836,485 RGD:10043621
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:11535102
RGD:1624291
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:1624291
RGD:1600115
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1600115
RGD:1624291
G Xylt1 xylosyltransferase 1 JBrowse link 1 186,939,698 187,264,758 RGD:1624291
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon JBrowse link 10 63,884,338 63,921,709 RGD:1624291
RGD:1600115
G Zfand1 zinc finger AN1-type containing 1 JBrowse link 2 93,656,895 93,666,745 RGD:1624291
G Zfp709 zinc finger protein 709 JBrowse link 16 19,632,954 19,643,956 RGD:8553966
cellular heat acclimation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsbp1 heat shock factor binding protein 1 JBrowse link 19 51,985,196 51,989,528 RGD:13792537
G Hsbp1l1 heat shock factor binding protein 1-like 1 JBrowse link 18 76,748,067 76,754,642 RGD:13792537
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Rbbp7 RB binding protein 7, chromatin remodeling factor JBrowse link X 33,648,682 33,665,821 RGD:1624291
RGD:1600115
mRNA export from nucleus in response to heat stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Polr2d RNA polymerase II subunit D JBrowse link 18 24,570,762 24,577,894 RGD:13792537
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1624291
RGD:1600115
negative regulation of cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
RGD:1600115
positive regulation of cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ier5 immediate early response 5 JBrowse link 13 72,742,210 72,744,302 RGD:1624291
RGD:1600115
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:1624291
RGD:13792537
G Hsf2 heat shock transcription factor 2 JBrowse link 20 38,935,820 38,963,444 RGD:13792537
G Hsf4 heat shock transcription factor 4 JBrowse link 19 37,225,800 37,232,048 RGD:13792537
G Hsf5 heat shock transcription factor 5 JBrowse link 10 74,909,621 74,954,128 RGD:13792537
G Hsfy2 heat shock transcription factor, Y linked 2 JBrowse link 9 63,289,937 63,291,350 RGD:13792537
regulation of cellular response to heat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link 8 17,421,552 17,445,513 RGD:1624291
RGD:1600115
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:1624291
RGD:1600115
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    response to stimulus 9859
      response to stress 3731
        response to heat 149
          cellular response to heat 79
            cellular heat acclimation 5
            heat shock-mediated polytene chromosome puffing 0
            mRNA export from nucleus in response to heat stress + 2
            negative regulation of cellular response to heat 1
            positive regulation of cellular response to heat 1
            positive regulation of transcription from RNA polymerase II promoter in response to heat stress 5
            regulation of cellular response to heat + 5
            trehalose metabolism in response to heat stress + 0
Path 2
Term Annotations click to browse term
  biological_process 18008
    response to stimulus 9859
      response to abiotic stimulus 1482
        response to temperature stimulus 240
          response to heat 149
            cellular response to heat 79
              cellular heat acclimation 5
              heat shock-mediated polytene chromosome puffing 0
              mRNA export from nucleus in response to heat stress + 2
              negative regulation of cellular response to heat 1
              positive regulation of cellular response to heat 1
              positive regulation of transcription from RNA polymerase II promoter in response to heat stress 5
              regulation of cellular response to heat + 5
              trehalose metabolism in response to heat stress + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.