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ONTOLOGY REPORT - ANNOTATIONS


Term:'de novo' NAD biosynthetic process
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Accession:GO:0034627 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


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'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Kmo kynurenine 3-monooxygenase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      biosynthetic process 6222
        cellular biosynthetic process 6056
          cellular nitrogen compound biosynthetic process 5075
            pyridine-containing compound biosynthetic process 24
              pyridine nucleotide biosynthetic process 19
                nicotinamide nucleotide biosynthetic process 19
                  NAD biosynthetic process 15
                    'de novo' NAD biosynthetic process 6
                      'de novo' NAD biosynthetic process from aspartate 0
                      'de novo' NAD biosynthetic process from tryptophan + 6
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular aromatic compound metabolic process 5700
          nucleobase-containing compound metabolic process 5488
            nucleobase-containing small molecule metabolic process 591
              nucleoside phosphate metabolic process 513
                nucleotide metabolic process 506
                  nucleotide biosynthetic process 248
                    pyridine nucleotide biosynthetic process 19
                      nicotinamide nucleotide biosynthetic process 19
                        NAD biosynthetic process 15
                          'de novo' NAD biosynthetic process 6
                            'de novo' NAD biosynthetic process from aspartate 0
                            'de novo' NAD biosynthetic process from tryptophan + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.