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ONTOLOGY REPORT - ANNOTATIONS


Term:CFTR-NHERF-ezrin complex
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Accession:GO:0034662 term browser browse the term
Definition:A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.


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  cellular_component 15532
    protein-containing complex 4875
      membrane protein complex 1125
        plasma membrane protein complex 543
          CFTR-NHERF-ezrin complex 0
Path 2
Term Annotations click to browse term
  cellular_component 15532
    cellular anatomical entity 15411
      membrane 8158
        plasma membrane 4598
          plasma membrane protein complex 543
            CFTR-NHERF-ezrin complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.