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Term:SMN-Sm protein complex
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Accession:GO:0034719 term browser browse the term
Definition:A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.
Comment:Note that this complex is sometimes referred to as the 'SMN complex', but it should not be confused with GO:0032797.
Synonyms:broad_synonym: SMN-containing protein complex

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SMN-Sm protein complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07042226.1 RGD:13792537
G Ddx20 DEAD-box helicase 20 JBrowse link 2 208,144,142 208,154,764 RGD:1624291
G Gemin2 gem (nuclear organelle) associated protein 2 JBrowse link 6 80,108,751 80,122,382 RGD:1624291
G Gemin4 gem (nuclear organelle) associated protein 4 JBrowse link 10 64,364,808 64,375,885 RGD:1624291
G Gemin5 gem (nuclear organelle) associated protein 5 JBrowse link 10 43,552,260 43,599,241 RGD:1624291
G Gemin6 gem (nuclear organelle) associated protein 6 JBrowse link 6 2,907,040 2,911,577 RGD:1624291
G Gemin7 gem (nuclear organelle) associated protein 7 JBrowse link 1 80,473,966 80,487,976 RGD:1624291
G Gemin7l1 gem (nuclear organelle) associated protein 7-like 1 JBrowse link 4 78,954,274 78,955,038 RGD:13792537
G Gemin8 gem (nuclear organelle) associated protein 8 JBrowse link X 29,806,605 29,825,439 RGD:1624291
G LOC687679 similar to small nuclear ribonucleoprotein polypeptide G JBrowse link 1 91,588,215 91,588,629 RGD:13792537
G Smn1 survival of motor neuron 1, telomeric JBrowse link 2 30,360,101 30,371,147 RGD:1624291
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 JBrowse link 3 122,696,125 122,703,734 RGD:1624291
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide JBrowse link 18 1,866,066 1,876,613 RGD:1624291
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide JBrowse link 1 80,057,140 80,059,990 RGD:1624291
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide JBrowse link 20 14,080,562 14,095,644 RGD:1624291
G Snrpe small nuclear ribonucleoprotein polypeptide E JBrowse link 13 50,252,707 50,258,951 RGD:1624291
G Snrpf small nuclear ribonucleoprotein polypeptide F JBrowse link 7 34,478,331 34,485,034 RGD:1624291
G Snrpg small nuclear ribonucleoprotein polypeptide G JBrowse link 4 118,167,267 118,174,846 RGD:1624291
G Strap serine/threonine kinase receptor associated protein JBrowse link 4 171,730,629 171,744,877 RGD:1624291

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  cellular_component 20118
    intracellular 14086
      cytoplasm 10966
        SMN-Sm protein complex 19
          Lsm-containing SMN-Sm protein complex 0
          SmD-containing SMN-Sm protein complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.