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ONTOLOGY REPORT - ANNOTATIONS


Term:response to endoplasmic reticulum stress
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Accession:GO:0034976 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
Synonyms:exact_synonym: ER stress response;   cellular response to endoplasmic reticulum stress;   response to ER stress


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response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07007642.1 RGD:1600115
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:8693588
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:1624291
RGD:1600115
G Anks4b ankyrin repeat and sterile alpha motif domain containing 4B JBrowse link 1 189,940,305 189,942,113 RGD:1624291
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:1600115
RGD:1624291
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 JBrowse link 1 197,855,912 197,875,038 RGD:1624291
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:10047286
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:1624291
RGD:1600115
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:2311465
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Cert1 ceramide transporter 1 JBrowse link 2 27,365,145 27,469,797 RGD:1624291
RGD:1600115
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:1600115
RGD:1624291
G Creb3 cAMP responsive element binding protein 3 JBrowse link 5 59,063,532 59,068,196 RGD:1624291
G Creb3l2 cAMP responsive element binding protein 3-like 2 JBrowse link 4 64,869,285 64,981,519 RGD:1624291
RGD:13515083
RGD:1600115
G Crebrf CREB3 regulatory factor JBrowse link 10 16,693,846 16,753,162 RGD:1624291
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1600115
RGD:1624291
G Ddrgk1 DDRGK domain containing 1 JBrowse link 3 123,195,580 123,206,828 RGD:1624291
RGD:1600115
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:1600115
RGD:1624291
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 JBrowse link 3 67,538,289 67,578,308 RGD:1624291
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 JBrowse link 15 104,186,918 104,226,236 RGD:1624291
G Eef2 eukaryotic translation elongation factor 2 JBrowse link 7 11,401,501 11,406,771 RGD:10401228
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
RGD:1600115
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 JBrowse link 3 110,159,624 110,245,382 RGD:1624291
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 11 84,080,273 84,090,259 RGD:1624291
RGD:1600115
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 6 102,048,372 102,073,041 RGD:1624291
RGD:1600115
G Elavl4 ELAV like RNA binding protein 4 JBrowse link 5 130,001,387 130,144,557 RGD:9685332
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:1624291
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha JBrowse link 15 19,619,947 19,655,381 RGD:1624291
RGD:1600115
G Erp27 endoplasmic reticulum protein 27 JBrowse link 4 170,893,946 170,912,629 RGD:13792537
G Erp29 endoplasmic reticulum protein 29 JBrowse link 12 40,619,377 40,625,884 RGD:10047223
G Erp44 endoplasmic reticulum protein 44 JBrowse link 5 63,937,866 64,030,827 RGD:1624291
RGD:1600115
G Ficd FIC domain containing JBrowse link 12 48,658,283 48,663,175 RGD:1600115
RGD:1624291
G Flot1 flotillin 1 JBrowse link 20 3,427,890 3,438,418 RGD:1624291
RGD:1600115
G Gorasp2 golgi reassembly stacking protein 2 JBrowse link 3 56,966,654 56,995,369 RGD:1600115
RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1304327
RGD:1624291
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:8554667
RGD:11354954
G Hyou1 hypoxia up-regulated 1 JBrowse link 8 48,699,796 48,711,912 RGD:1624291
RGD:1600115
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:1624291
RGD:2298760
G Nfe2l1 nuclear factor, erythroid 2-like 1 JBrowse link 10 84,686,762 84,699,313 RGD:1600115
RGD:1624291
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
G Nhlrc1 NHL repeat containing E3 ubiquitin protein ligase 1 JBrowse link 17 18,059,382 18,060,572 RGD:1600115
RGD:1624291
G Niban1 niban apoptosis regulator 1 JBrowse link 13 68,949,665 69,101,600 RGD:1624291
RGD:1600115
G Nrbf2 nuclear receptor binding factor 2 JBrowse link 20 22,728,145 22,746,477 RGD:1600115
RGD:1624291
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:1624291
G P4hb prolyl 4-hydroxylase subunit beta JBrowse link 10 109,736,459 109,748,070 RGD:1624291
RGD:13792537
G Pdia3 protein disulfide isomerase family A, member 3 JBrowse link 3 113,376,983 113,400,707 RGD:13792537
G Pdia4 protein disulfide isomerase family A, member 4 JBrowse link 4 77,470,636 77,489,535 RGD:13792537
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1600115
RGD:1624291
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 16 20,415,109 20,424,982 RGD:1600115
RGD:1624291
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6482749
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1624291
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
RGD:13792537
RGD:9999412
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B JBrowse link 13 49,933,155 49,940,961 RGD:1624291
RGD:13792537
G Ppp2cb protein phosphatase 2 catalytic subunit beta JBrowse link 16 62,273,276 62,294,767 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
RGD:10413862
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1600115
RGD:1624291
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 JBrowse link 2 21,460,041 21,698,937 RGD:1624291
G Rnf183 ring finger protein 183 JBrowse link 5 78,283,722 78,292,729 RGD:1600115
RGD:1624291
G Scamp5 secretory carrier membrane protein 5 JBrowse link 8 62,221,820 62,266,269 RGD:1600115
RGD:1624291
G Sdf2l1 stromal cell-derived factor 2-like 1 JBrowse link 11 88,122,271 88,124,513 RGD:8554667
G Sec16a SEC16 homolog A, endoplasmic reticulum export factor JBrowse link 3 3,856,218 3,890,785 RGD:1624291
RGD:1600115
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase JBrowse link 6 115,572,683 115,616,904 RGD:1624291
G Srpx sushi-repeat-containing protein, X-linked JBrowse link X 14,146,618 14,220,756 RGD:1624291
RGD:1600115
G Stc2 stanniocalcin 2 JBrowse link 10 16,542,909 16,552,675 RGD:1624291
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:5687138
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
G Thbs4 thrombospondin 4 JBrowse link 2 22,343,727 22,385,855 RGD:1600115
RGD:13792537
RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
G Tmem259 transmembrane protein 259 JBrowse link 7 12,771,239 12,777,901 RGD:1624291
RGD:13792537
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 JBrowse link 7 40,171,957 40,217,056 RGD:1624291
RGD:1600115
G Tmx1 thioredoxin-related transmembrane protein 1 JBrowse link 6 92,864,123 92,875,141 RGD:1624291
RGD:1600115
G Trib3 tribbles pseudokinase 3 JBrowse link 3 147,814,056 147,819,650 RGD:1624291
RGD:1600115
G Uba5 ubiquitin-like modifier activating enzyme 5 JBrowse link 8 112,578,607 112,594,192 RGD:1624291
RGD:1600115
G Ube4b ubiquitination factor E4B JBrowse link 5 166,156,033 166,259,069 RGD:1624291
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1624291
G Ufc1 ubiquitin-fold modifier conjugating enzyme 1 JBrowse link 13 89,661,763 89,668,513 RGD:1624291
RGD:1600115
G Ufl1 Ufm1-specific ligase 1 JBrowse link 5 39,616,479 39,650,894 RGD:1624291
RGD:13792537
G Ufm1 ubiquitin-fold modifier 1 JBrowse link 2 143,096,268 143,104,412 RGD:1624291
RGD:1600115
G Usp19 ubiquitin specific peptidase 19 JBrowse link 8 117,280,690 117,291,729 RGD:1624291
RGD:1600115
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
eiF2alpha phosphorylation in response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
RGD:1600115
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 JBrowse link 3 110,159,624 110,245,382 RGD:1624291
RGD:1600115
endoplasmic reticulum stress-induced pre-emptive quality control term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
RGD:1600115
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291
RGD:1600115
endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amfr autocrine motility factor receptor JBrowse link 19 11,473,538 11,509,500 RGD:1624291
RGD:13792537
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:1624291
RGD:1600115
G Atf6 activating transcription factor 6 JBrowse link 13 89,053,457 89,242,531 RGD:1600115
G Atf6b activating transcription factor 6 beta JBrowse link 20 4,414,283 4,422,283 RGD:1600115
G Bhlha15 basic helix-loop-helix family, member a15 JBrowse link 12 12,403,385 12,409,103 RGD:1624291
RGD:1600115
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:13792537
G Calr3 calreticulin 3 JBrowse link 16 19,097,391 19,124,062 RGD:13792537
G Calr4 calreticulin 4 JBrowse link 5 128,865,339 128,900,135 RGD:13792537
G Canx calnexin JBrowse link 10 35,800,942 35,833,939 RGD:13792537
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 JBrowse link 10 84,780,644 84,789,800 RGD:1600115
RGD:1624291
G Clgn calmegin JBrowse link 19 24,545,257 24,578,527 RGD:13792537
G Creb3 cAMP responsive element binding protein 3 JBrowse link 5 59,063,532 59,068,196 RGD:1600115
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:1624291
RGD:1600115
G Creb3l2 cAMP responsive element binding protein 3-like 2 JBrowse link 4 64,869,285 64,981,519 RGD:1600115
G Creb3l3 cAMP responsive element binding protein 3-like 3 JBrowse link 7 11,490,852 11,499,287 RGD:1600115
G Creb3l4 cAMP responsive element binding protein 3-like 4 JBrowse link 2 189,596,657 189,602,243 RGD:1600115
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1624291
RGD:1600115
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:1624291
RGD:13792537
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
RGD:13792537
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
RGD:13792537
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 JBrowse link 6 1,428,845 1,466,193 RGD:1624291
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1600115
RGD:1624291
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 JBrowse link 3 110,159,624 110,245,382 RGD:1624291
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
RGD:13792537
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:13792537
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha JBrowse link 15 19,619,947 19,655,381 RGD:1624291
RGD:1600115
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:10401883
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1304324
RGD:13792537
RGD:1624291
G Herpud2 HERPUD family member 2 JBrowse link 8 26,266,571 26,311,528 RGD:13792537
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1624291
RGD:13792537
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
RGD:1600115
G LOC103694875 derlin-3 RGD:13792537
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
G Parp16 poly (ADP-ribose) polymerase family, member 16 JBrowse link 8 70,712,393 70,731,212 RGD:1624291
RGD:13792537
G Parp6 poly (ADP-ribose) polymerase family, member 6 JBrowse link 8 64,439,933 64,472,443 RGD:13792537
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
RGD:9999413
RGD:9999171
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
RGD:1600115
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1600115
RGD:13792537
RGD:1624291
G Serp1 stress-associated endoplasmic reticulum protein 1 JBrowse link 2 148,718,279 148,722,263 RGD:1624291
RGD:13792537
G Serp2 stress-associated endoplasmic reticulum protein family member 2 JBrowse link 15 58,687,784 58,712,023 RGD:13792537
G Stc2 stanniocalcin 2 JBrowse link 10 16,542,909 16,552,675 RGD:1624291
RGD:1600115
G Stub1 STIP1 homology and U-box containing protein 1 JBrowse link 10 15,197,754 15,200,035 RGD:1624291
RGD:1600115
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:13792537
G Tbl2 transducin (beta)-like 2 JBrowse link 12 24,565,843 24,578,855 RGD:1624291
RGD:1600115
G Vapb VAMP associated protein B and C JBrowse link 3 171,832,558 171,871,042 RGD:1624291
RGD:1600115
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
RGD:1600115
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1304536
RGD:1624291
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1624291
RGD:13792537
RGD:1600115
ER overload response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg10 autophagy related 10 JBrowse link 2 19,853,546 20,152,918 RGD:1624291
RGD:1600115
G Ccdc47 coiled-coil domain containing 47 JBrowse link 10 94,388,425 94,406,949 RGD:1624291
RGD:1600115
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:70575
RGD:13792537
RGD:1600115
RGD:1624291
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1600115
RGD:1624291
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:1624291
RGD:1600115
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1624291
RGD:1600115
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
RGD:1600115
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B JBrowse link 13 49,933,155 49,940,961 RGD:1624291
RGD:1600115
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1600115
RGD:1624291
G Tmco1 transmembrane and coiled-coil domains 1 JBrowse link 13 85,465,015 85,559,113 RGD:1624291
RGD:1600115
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
RGD:1600115
ER-associated misfolded protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:1600115
RGD:1624291
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:1624291
RGD:1600115
G Pomt2 protein-O-mannosyltransferase 2 JBrowse link 6 111,137,329 111,176,991 RGD:13792537
G Rnf185 ring finger protein 185 JBrowse link 14 83,648,400 83,685,273 RGD:13792537
G Rnf5 ring finger protein 5 JBrowse link 20 4,366,244 4,368,690 RGD:1624291
RGD:13792537
G Sdf2l1 stromal cell-derived factor 2-like 1 JBrowse link 11 88,122,271 88,124,513 RGD:8554667
G Tor1a torsin family 1, member A JBrowse link 3 9,800,322 9,807,318 RGD:1624291
RGD:1600115
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 11 86,304,836 86,328,478 RGD:1624291
RGD:1600115
G Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 JBrowse link 9 42,692,156 42,805,680 RGD:13792537
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291
RGD:13792537
ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brsk2 BR serine/threonine kinase 2 JBrowse link 1 214,918,757 214,940,883 RGD:1624291
RGD:1600115
G Ccdc47 coiled-coil domain containing 47 JBrowse link 10 94,388,425 94,406,949 RGD:1600115
RGD:1624291
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:1624291
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 JBrowse link 20 29,445,510 29,463,739 RGD:1624291
G Rcn3 reticulocalbin 3 JBrowse link 1 101,076,971 101,086,198 RGD:1600115
RGD:1624291
G Rhbdd1 rhomboid domain containing 1 JBrowse link 9 88,110,731 88,229,462 RGD:1624291
RGD:1600115
G Rnf139 ring finger protein 139 JBrowse link 7 98,770,840 98,782,025 RGD:1624291
RGD:13792537
G Rnf185 ring finger protein 185 JBrowse link 14 83,648,400 83,685,273 RGD:1624291
G Rnf5 ring finger protein 5 JBrowse link 20 4,366,244 4,368,690 RGD:1624291
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase JBrowse link 6 115,572,683 115,616,904 RGD:1624291
RGD:1600115
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:1624291
G Ubxn6 UBX domain protein 6 JBrowse link 9 10,995,516 11,000,643 RGD:1624291
RGD:1600115
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1600115
RGD:1624291
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:1624291
RGD:1600115
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
RGD:1600115
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:1624291
RGD:1600115
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 JBrowse link 1 197,855,912 197,875,038 RGD:1624291
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 JBrowse link 10 59,528,849 59,560,440 RGD:1624291
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
RGD:1600115
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
RGD:1600115
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:1624291
RGD:13792537
RGD:1600115
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Brsk2 BR serine/threonine kinase 2 JBrowse link 1 214,918,757 214,940,883 RGD:1624291
RGD:1600115
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:10047306
RGD:1600115
RGD:1624291
G Casp4 caspase 4 JBrowse link 8 2,616,391 2,651,682 RGD:1624291
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 JBrowse link 3 111,160,205 111,163,425 RGD:1624291
RGD:1600115
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1624291
RGD:1600115
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1600115
RGD:13792537
RGD:1624291
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 JBrowse link 3 67,538,289 67,578,308 RGD:1624291
RGD:1600115
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
RGD:13792537
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:1624291
RGD:13792537
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha JBrowse link 15 19,619,947 19,655,381 RGD:1624291
RGD:1600115
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:1624291
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
RGD:1600115
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 JBrowse link 4 140,247,297 140,580,749 RGD:1600115
RGD:1624291
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:1624291
RGD:1600115
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
RGD:1600115
G Rnf186 ring finger protein 186 JBrowse link 5 157,416,897 157,418,121 RGD:1624291
RGD:13792537
G Selenok selenoprotein K JBrowse link 16 6,035,926 6,044,240 RGD:1600115
RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
G Tmem117 transmembrane protein 117 JBrowse link 7 135,880,294 136,403,012 RGD:1624291
RGD:13792537
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
RGD:1600115
G Trib3 tribbles pseudokinase 3 JBrowse link 3 147,814,056 147,819,650 RGD:1624291
RGD:1600115
G Ube2k ubiquitin-conjugating enzyme E2K JBrowse link 14 44,289,247 44,348,691 RGD:8554156
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
RGD:13792537
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:13792537
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1624291
G Parp16 poly (ADP-ribose) polymerase family, member 16 JBrowse link 8 70,712,393 70,731,212 RGD:1600115
RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
RGD:1600115
G Vapb VAMP associated protein B and C JBrowse link 3 171,832,558 171,871,042 RGD:1600115
RGD:1624291
maintenance of unfolded protein involved in ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
RGD:1600115
G Get4 guided entry of tail-anchored proteins factor 4 JBrowse link 12 17,469,112 17,486,709 RGD:1624291
RGD:1600115
G Usp13 ubiquitin specific peptidase 13 JBrowse link 2 119,197,153 119,317,507 RGD:1624291
RGD:1600115
mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
RGD:1600115
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1624291
RGD:1600115
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 JBrowse link 13 69,135,095 69,197,708 RGD:1624291
RGD:1600115
G Man1b1 mannosidase, alpha, class 1B, member 1 JBrowse link 3 2,547,259 2,569,051 RGD:1624291
RGD:1600115
membrane protein proteolysis involved in retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hm13 histocompatibility minor 13 JBrowse link 3 148,150,695 148,189,623 RGD:1624291
RGD:1600115
G Rhbdd1 rhomboid domain containing 1 JBrowse link 9 88,110,731 88,229,462 RGD:1624291
RGD:1600115
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf6b activating transcription factor 6 beta JBrowse link 20 4,414,283 4,422,283 RGD:1600115
RGD:1624291
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
RGD:10047363
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 JBrowse link 15 104,186,918 104,226,236 RGD:1624291
RGD:1600115
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
RGD:1600115
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
RGD:1600115
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B JBrowse link 13 49,933,155 49,940,961 RGD:1624291
RGD:1600115
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1600115
RGD:1624291
G Creb3 cAMP responsive element binding protein 3 JBrowse link 5 59,063,532 59,068,196 RGD:1624291
RGD:1600115
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:1558627
RGD:1624291
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 JBrowse link 7 117,304,742 117,307,916 RGD:1624291
RGD:1600115
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1304324
RGD:13792537
RGD:1624291
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:10047230
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
RGD:1600115
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
RGD:1600115
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1624291
RGD:1600115
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:1624291
RGD:1600115
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
RGD:1600115
G Txndc12 thioredoxin domain containing 12 JBrowse link 5 128,450,830 128,475,858 RGD:1624291
RGD:1600115
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
RGD:1600115
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:10047191
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hyou1 hypoxia up-regulated 1 JBrowse link 8 48,699,796 48,711,912 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crebrf CREB3 regulatory factor JBrowse link 10 16,693,846 16,753,162 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
RGD:1600115
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:10047192
RGD:1624291
G Usp14 ubiquitin specific peptidase 14 JBrowse link 18 1,178,785 1,216,573 RGD:1624291
RGD:1600115
negative regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp11 aquaporin 11 JBrowse link 1 162,703,394 162,713,560 RGD:1600115
G Ubxn1 UBX domain protein 1 JBrowse link 1 225,067,953 225,071,944 RGD:1624291
RGD:1600115
G Usp25 ubiquitin specific peptidase 25 JBrowse link 11 15,436,080 15,558,646 RGD:1624291
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bfar bifunctional apoptosis regulator JBrowse link 10
10
1,464,658
1,464,783
1,471,152
1,497,653
RGD:1624291
RGD:13792537
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:1600115
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1600115
G Pdia6 protein disulfide isomerase family A, member 6 JBrowse link 6 42,568,269 42,585,654 RGD:1624291
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
RGD:1600115
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
RGD:1600115
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
RGD:1600115
negative regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp11 aquaporin 11 JBrowse link 1 162,703,394 162,713,560 RGD:1600115
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
negative regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
RGD:1600115
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:1624291
RGD:1600115
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:1624291
RGD:1600115
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:1624291
RGD:1600115
G Ubac2 UBA domain containing 2 JBrowse link 15 108,286,407 108,433,531 RGD:1624291
RGD:1600115
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 20 11,700,089 11,721,823 RGD:1624291
RGD:1600115
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 JBrowse link 5 48,274,387 48,292,699 RGD:1624291
RGD:1600115
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1600115
RGD:1624291
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:1624291
RGD:1600115
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
RGD:1600115
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
RGD:1600115
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
negative regulation of translation in response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:1624291
RGD:1600115
PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:1624291
RGD:1600115
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
RGD:1600115
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf6 activating transcription factor 6 JBrowse link 13 89,053,457 89,242,531 RGD:1600115
RGD:1624291
positive regulation of autophagy in response to ER overload term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:13782257
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:13782257
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:13782257
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1600115
RGD:1624291
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
RGD:1600115
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Rnf183 ring finger protein 183 JBrowse link 5 78,283,722 78,292,729 RGD:1600115
RGD:1624291
G Serinc3 serine incorporator 3 JBrowse link 3 160,018,643 160,038,078 RGD:1624291
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Spop speckle type BTB/POZ protein JBrowse link 10 83,231,187 83,311,987 RGD:1624291
RGD:1600115
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
RGD:1600115
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1624291
RGD:1600115
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:1600115
RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:13792537
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:10047316
RGD:1624291
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
RGD:1600115
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1600115
RGD:1624291
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
RGD:1600115
positive regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:1624291
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
RGD:1600115
G Rnf185 ring finger protein 185 JBrowse link 14 83,648,400 83,685,273 RGD:1600115
RGD:1624291
G Rnft1 ring finger protein, transmembrane 1 JBrowse link 10 73,807,455 73,821,178 RGD:1600115
RGD:1624291
G Tmem259 transmembrane protein 259 JBrowse link 7 12,771,239 12,777,901 RGD:1624291
RGD:13792537
G Tmem67 transmembrane protein 67 JBrowse link 5 25,666,138 25,721,056 RGD:8554391
G Usp13 ubiquitin specific peptidase 13 JBrowse link 2 119,197,153 119,317,507 RGD:1624291
RGD:1600115
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
RGD:1600115
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
RGD:1600115
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291
positive regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:12910988
RGD:1624291
positive regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
RGD:1600115
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
RGD:1600115
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1624291
RGD:1600115
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:1624291
RGD:1600115
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:1624291
RGD:13792537
G Atf6 activating transcription factor 6 JBrowse link 13 89,053,457 89,242,531 RGD:1624291
RGD:1600115
G Atf6b activating transcription factor 6 beta JBrowse link 20 4,414,283 4,422,283 RGD:1624291
RGD:1600115
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:1558627
RGD:1624291
G Creb3l3 cAMP responsive element binding protein 3-like 3 JBrowse link 7 11,490,852 11,499,287 RGD:1624291
RGD:1600115
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1599740
RGD:13792537
RGD:1624291
RGD:1600115
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Mbtps2 membrane-bound transcription factor peptidase, site 2 JBrowse link X 40,258,933 40,309,047 RGD:1624291
RGD:13792537
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
RGD:1600115
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Creb3 cAMP responsive element binding protein 3 JBrowse link 5 59,063,532 59,068,196 RGD:1624291
RGD:1600115
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:13792537
RGD:1600115
positive regulation of translation in response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
RGD:1600115
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
RGD:1600115
positive regulation of translation initiation in response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 JBrowse link 15 104,186,918 104,226,236 RGD:1624291
RGD:1600115
protein localization to cytosolic proteasome complex involved in ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:1624291
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
RGD:1600115
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
RGD:1600115
G Erp29 endoplasmic reticulum protein 29 JBrowse link 12 40,619,377 40,625,884 RGD:1624291
RGD:1600115
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1624291
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1624291
RGD:13792537
regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Usp19 ubiquitin specific peptidase 19 JBrowse link 8 117,280,690 117,291,729 RGD:1624291
RGD:1600115
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cops5 COP9 signalosome subunit 5 JBrowse link 5 8,876,090 8,894,345 RGD:1624291
RGD:1600115
G Ficd FIC domain containing JBrowse link 12 48,658,283 48,663,175 RGD:1600115
RGD:1624291
regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Manf mesencephalic astrocyte-derived neurotrophic factor JBrowse link 8 115,623,175 115,626,408 RGD:1624291
G Nfe2l1 nuclear factor, erythroid 2-like 1 JBrowse link 10 84,686,762 84,699,313 RGD:1600115
RGD:1624291
G Nupr1 nuclear protein 1, transcriptional regulator JBrowse link 1 194,767,484 194,769,519 RGD:1600115
RGD:1624291
RGD:14390049
response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:10047151
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:10047151
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 6 102,048,372 102,073,041 RGD:10047151
retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor JBrowse link 4 113,887,030 113,890,103 RGD:1624291
RGD:1600115
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:1624291
RGD:1600115
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
RGD:1600115
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:13792537
G Faf2 Fas associated factor family member 2 JBrowse link 17 10,485,650 10,527,886 RGD:1624291
RGD:1600115
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1624291
RGD:1600115
G Hsp90b1 heat shock protein 90 beta family member 1 JBrowse link 7 27,226,570 27,240,533 RGD:1624291
RGD:1600115
G Nploc4 NPL4 homolog, ubiquitin recognition factor JBrowse link 10 109,553,518 109,610,087 RGD:1624291
RGD:1600115
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:13792537
G Sec61b Sec61 translocon beta subunit JBrowse link 5 63,192,322 63,200,532 RGD:1624291
RGD:1600115
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase JBrowse link 6 115,572,683 115,616,904 RGD:1624291
RGD:1600115
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1600115
RGD:13792537
RGD:1624291
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:1624291
RGD:13792537
G Tmem129 transmembrane protein 129 JBrowse link 14 82,350,734 82,356,084 RGD:1624291
RGD:1600115
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 11 86,304,836 86,328,478 RGD:1624291
RGD:1600115
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291
RGD:13792537
ubiquitin-dependent ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07002848.1 RGD:13792537
G Amfr autocrine motility factor receptor JBrowse link 19 11,473,538 11,509,500 RGD:1624291
RGD:1600115
G Ankzf1 ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1 JBrowse link 9 82,393,619 82,400,537 RGD:13792537
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor JBrowse link 4 113,887,030 113,890,103 RGD:13792537
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:1600115
RGD:13792537
RGD:1624291
G Ccdc47 coiled-coil domain containing 47 JBrowse link 10 94,388,425 94,406,949 RGD:1624291
RGD:1600115
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:1624291
RGD:13792537
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
RGD:13792537
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
RGD:13792537
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 JBrowse link 20 29,445,510 29,463,739 RGD:13792537
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 JBrowse link 2 243,108,443 243,151,933 RGD:13792537
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 9 82,436,453 82,444,669 RGD:1624291
RGD:13792537
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:1624291
RGD:1600115
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 JBrowse link 3 67,538,289 67,578,308 RGD:1624291
RGD:1600115
G Dnajc18 DnaJ heat shock protein family (Hsp40) member C18 JBrowse link 18 28,466,892 28,501,013 RGD:13792537
G Ecpas Ecm29 proteasome adaptor and scaffold JBrowse link 5 75,928,510 76,040,771 RGD:1624291
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:1624291
RGD:13792537
G Erlin1 ER lipid raft associated 1 JBrowse link 1 263,810,439 263,845,762 RGD:1624291
RGD:1600115
G Erlin2 ER lipid raft associated 2 JBrowse link 16 69,179,005 69,195,452 RGD:1624291
RGD:1600115
G Faf2 Fas associated factor family member 2 JBrowse link 17 10,485,650 10,527,886 RGD:1600115
RGD:1624291
G Fbxo17 F-box protein 17 JBrowse link 1 86,903,762 86,919,238 RGD:13792537
G Fbxo2 F-box protein 2 JBrowse link 5 164,972,483 164,977,912 RGD:1624291
RGD:13792537
G Fbxo44 F-box protein 44 JBrowse link 5 164,962,921 164,972,273 RGD:13792537
G Fbxo6 F-box protein 6 JBrowse link 5 164,956,285 164,962,075 RGD:1624291
RGD:13792537
RGD:1600115
G Foxred2 FAD-dependent oxidoreductase domain containing 2 JBrowse link 7 119,172,189 119,186,670 RGD:1624291
RGD:13792537
G Hsp90b1 heat shock protein 90 beta family member 1 JBrowse link 7 27,226,570 27,240,533 RGD:1600115
RGD:13792537
RGD:1624291
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:13792537
G Jkamp JNK1/MAPK8-associated membrane protein JBrowse link 6 94,835,845 94,849,784 RGD:1624291
G LOC103694875 derlin-3 RGD:13792537
G Man1b1 mannosidase, alpha, class 1B, member 1 JBrowse link 3 2,547,259 2,569,051 RGD:1624291
RGD:13792537
G Marchf6 membrane associated ring-CH-type finger 6 JBrowse link 2 84,533,546 84,608,743 RGD:13792537
G Nccrp1 NCCRP1, F-box associated domain containing JBrowse link 1
1
85,558,420
85,213,578
85,559,652
85,218,030
RGD:13792537
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:1600115
RGD:13792537
RGD:1624291
G Psmc6 proteasome 26S subunit, ATPase 6 JBrowse link 15 19,667,453 19,688,916 RGD:13792537
G Rnf103 ring finger protein 103 JBrowse link 4 99,398,479 99,415,193 RGD:1600115
RGD:1624291
G Rnf121 ring finger protein 121 JBrowse link 1 167,095,916 167,165,257 RGD:13792537
G Rnf185 ring finger protein 185 JBrowse link 14 83,648,400 83,685,273 RGD:1624291
RGD:1600115
G Rnf5 ring finger protein 5 JBrowse link 20 4,366,244 4,368,690 RGD:1600115
RGD:1624291
G Sec61b Sec61 translocon beta subunit JBrowse link 5 63,192,322 63,200,532 RGD:1624291
RGD:1600115
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase JBrowse link 6 115,572,683 115,616,904 RGD:13792537
G Sel1l2 SEL1L2 adaptor subunit of ERAD E3 ligase JBrowse link 3 134,281,809 134,406,560 RGD:13792537
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1600115
RGD:13792537
RGD:1624291
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
RGD:13792537
RGD:1600115
G Sgtb small glutamine rich tetratricopeptide repeat containing beta JBrowse link 2 34,185,938 34,222,428 RGD:13792537
G Stt3b STT3 oligosaccharyltransferase complex catalytic subunit B JBrowse link 8 123,303,910 123,370,729 RGD:1624291
RGD:1600115
G Stub1 STIP1 homology and U-box containing protein 1 JBrowse link 10 15,197,754 15,200,035 RGD:1600115
RGD:1624291
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:1624291
RGD:13792537
G Tmem129 transmembrane protein 129 JBrowse link 14 82,350,734 82,356,084 RGD:1624291
RGD:1600115
G Tmem67 transmembrane protein 67 JBrowse link 5 25,666,138 25,721,056 RGD:1600115
RGD:1624291
G Tmub1 transmembrane and ubiquitin-like domain containing 1 JBrowse link 4 7,257,752 7,260,318 RGD:1624291
RGD:1600115
G Tmub2 transmembrane and ubiquitin-like domain containing 2 JBrowse link 10 90,230,428 90,234,874 RGD:1600115
G Trim13 tripartite motif-containing 13 JBrowse link 15 41,897,191 41,936,545 RGD:1624291
RGD:1600115
G Trim25 tripartite motif-containing 25 JBrowse link 10 76,343,847 76,362,159 RGD:1600115
RGD:1624291
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 20 11,700,089 11,721,823 RGD:1624291
RGD:13792537
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 JBrowse link 5 48,274,387 48,292,699 RGD:1624291
RGD:1600115
G Ube2j2 ubiquitin-conjugating enzyme E2, J2 JBrowse link 5 173,372,659 173,387,084 RGD:1624291
RGD:13792537
G Ube4a ubiquitination factor E4A JBrowse link 8 49,229,713 49,271,894 RGD:13792537
G Ube4b ubiquitination factor E4B JBrowse link 5 166,156,033 166,259,069 RGD:13792537
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1600115
RGD:13792537
RGD:1624291
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
RGD:13792537
G Ubxn4 UBX domain protein 4 JBrowse link 13 44,956,963 44,989,653 RGD:1624291
RGD:1600115
G Ubxn8 UBX domain protein 8 JBrowse link 16 62,251,243 62,272,838 RGD:1624291
RGD:1600115
G Usp19 ubiquitin specific peptidase 19 JBrowse link 8 117,280,690 117,291,729 RGD:1600115
RGD:13792537
RGD:1624291
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1600115
RGD:13792537
RGD:1624291
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
RGD:1600115
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1624291
RGD:13792537
RGD:1600115
ubiquitin-dependent glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1624291

Term paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.