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ONTOLOGY REPORT - ANNOTATIONS


Term:somatic stem cell population maintenance
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Accession:GO:0035019 term browser browse the term
Definition:Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.


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somatic stem cell population maintenance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO MGI:MGI:104642|MGI:MGI:1856318 (MGI:MGI:50403|PMID:1541640) RGD PMID:1541640 MGI:MGI:50403 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 ISO MGI:MGI:3846671 (MGI:MGI:3846269|PMID:19269367) RGD PMID:19269367 MGI:MGI:3846269 NCBI chr 1:216,154,002...216,156,409
Ensembl chr 1:216,154,002...216,156,409
JBrowse link
G Bcl9 BCL9, transcription coactivator ISO MGI:MGI:1933114 (MGI:MGI:4819869|PMID:20682801) RGD PMID:20682801 MGI:MGI:4819869 NCBI chr 2:199,334,644...199,420,083
Ensembl chr 2:199,334,664...199,354,793
JBrowse link
G Bcl9l BCL9 like ISO MGI:MGI:1924828 (MGI:MGI:4819869|PMID:20682801) RGD PMID:20682801 MGI:MGI:4819869 NCBI chr 8:48,805,684...48,835,794
Ensembl chr 8:48,805,684...48,834,312
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO MGI:MGI:97847 (MGI:MGI:5487489|PMID:23022482) RGD PMID:23022482 MGI:MGI:5487489 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO MGI:MGI:101761 (MGI:MGI:3829847|PMID:18957199) RGD PMID:18957199 MGI:MGI:3829847 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdx2 caudal type homeo box 2 ISO MGI:MGI:1857928 (MGI:MGI:3612803|PMID:16325584), (MGI:MGI:4819480|PMID:20404091) RGD PMID:16325584, PMID:20404091 MGI:MGI:3612803, MGI:MGI:4819480 NCBI chr12:9,464,026...9,470,565
Ensembl chr12:9,464,026...9,470,565
JBrowse link
G Cul4a cullin 4A ISO MGI:MGI:2183544 (MGI:MGI:3839083|PMID:17616641) RGD PMID:17616641 MGI:MGI:3839083 NCBI chr16:81,718,784...81,756,653
Ensembl chr16:81,719,028...81,756,654
JBrowse link
G Elf5 E74 like ETS transcription factor 5 ISO (MGI:MGI:5604337|PMID:24859262) RGD PMID:24859262 MGI:MGI:5604337 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656
JBrowse link
G Fgf10 fibroblast growth factor 10 ISO MGI:MGI:1859647 (MGI:MGI:2159281|PMID:11880361) RGD PMID:11880361 MGI:MGI:2159281 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO MGI:MGI:1931521 (MGI:MGI:4352984|PMID:19407216) RGD PMID:19407216 MGI:MGI:4352984 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Gata2 GATA binding protein 2 ISO (MGI:MGI:3589329|PMID:16082385) RGD PMID:16082385 MGI:MGI:3589329 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO
IEA
MGI:MGI:2149672 (MGI:MGI:1351379|PMID:10615124)
GO_REF:0000107
RGD
Ensembl
PMID:10615124 GO_REF:0000107, MGI:MGI:1351379 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hmga2 high mobility group AT-hook 2 ISO MGI:MGI:104738|MGI:MGI:2386412 (MGI:MGI:3829847|PMID:18957199) RGD PMID:18957199 MGI:MGI:3829847 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Kat6a lysine acetyltransferase 6A ISO MGI:MGI:3626344 (MGI:MGI:3624066|PMID:16651658), (MGI:MGI:3624570|PMID:16702405) RGD PMID:16651658, PMID:16702405 MGI:MGI:3624066, MGI:MGI:3624570 NCBI chr16:73,942,669...74,020,750
Ensembl chr16:73,943,455...74,023,005
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IMP neural stem cells from the ciliary epithelium of the eye RGD PMID:15302600 RGD:2292509 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Klf10 Kruppel-like factor 10 ISO (MGI:MGI:3850801|PMID:19379700) RGD PMID:19379700 MGI:MGI:3850801 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Ldb1 LIM domain binding 1 ISO MGI:MGI:109360 (MGI:MGI:3768693|PMID:17991461) RGD PMID:17991461 MGI:MGI:3768693 NCBI chr 1:265,772,729...265,798,442
Ensembl chr 1:265,785,409...265,798,167
JBrowse link
G Ldb2 LIM domain binding 2 ISO MGI:MGI:894762 (MGI:MGI:3768693|PMID:17991461) RGD PMID:17991461 MGI:MGI:3768693 NCBI chr14:70,780,605...71,112,857
Ensembl chr14:70,780,623...71,112,552
JBrowse link
G Lig4 DNA ligase 4 ISO MGI:MGI:3714783 (MGI:MGI:3715270|PMID:17554302) RGD PMID:17554302 MGI:MGI:3715270 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Lrp5 LDL receptor related protein 5 ISO MGI:MGI:3663738 (MGI:MGI:4358817|PMID:19672307) RGD PMID:19672307 MGI:MGI:4358817 NCBI chr 1:218,816,833...218,920,147
Ensembl chr 1:218,816,841...218,920,094
JBrowse link
G Nanog Nanog homeobox ISO (PMID:18388306) RGD PMID:18388306 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nog noggin ISO
IEA
(PMID:17889703)
GO_REF:0000107
RGD
Ensembl
PMID:17889703 GO_REF:0000107 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 ISO MGI:MGI:2151350|MGI:MGI:2176560|MGI:MGI:3764730|MGI:MGI:3807544 (MGI:MGI:2686847|PMID:14702088), (MGI:MGI:3527227|PMID:12527005), (MGI:MGI:3806374|PMID:18794344) RGD PMID:12527005, PMID:14702088, PMID:18794344 MGI:MGI:2686847, MGI:MGI:3527227, MGI:MGI:3806374 NCBI chr20:47,286,843...47,306,318
Ensembl chr20:47,288,137...47,306,318
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:18388306), (PMID:19409607), (PMID:19736317) RGD PMID:18388306, PMID:19409607, PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Prdm16 PR/SET domain 16 ISO (MGI:MGI:3850801|PMID:19379700) RGD PMID:19379700 MGI:MGI:3850801 NCBI chr 5:171,662,277...171,711,561
Ensembl chr 5:171,662,277...171,710,316
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO MGI:MGI:88190 (MGI:MGI:5487489|PMID:23022482) RGD PMID:23022482 MGI:MGI:5487489 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO MGI:MGI:3583755 (MGI:MGI:5292802|PMID:21402740) RGD PMID:21402740 MGI:MGI:5292802 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Rest RE1-silencing transcription factor ISS
ISO
GO_REF:0000024
(MGI:MGI:5906102|PMID:27819263)
UniProt
RGD
PMID:27819263 GO_REF:0000024, MGI:MGI:5906102 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO
IEA
MGI:MGI:3621116 (MGI:MGI:4356203|PMID:19664990)
GO_REF:0000107
RGD
Ensembl
PMID:19664990 GO_REF:0000107, MGI:MGI:4356203 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Ski SKI proto-oncogene ISO (MGI:MGI:3850801|PMID:19379700) RGD PMID:19379700 MGI:MGI:3850801 NCBI chr 5:172,556,196...172,623,878
Ensembl chr 5:172,559,135...172,623,899
JBrowse link
G Sox2 SRY-box transcription factor 2 ISO (PMID:18388306), (PMID:19409607), (PMID:19736317) RGD PMID:18388306, PMID:19409607, PMID:19736317 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Sox4 SRY-box transcription factor 4 ISO (MGI:MGI:3850801|PMID:19379700) RGD PMID:19379700 MGI:MGI:3850801 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO
ISS
MGI:MGI:2176173|MGI:MGI:2429649 (MGI:MGI:4836759|PMID:20871603)
GO_REF:0000024
RGD
UniProt
PMID:20871603 GO_REF:0000024, MGI:MGI:4836759 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Spi1 Spi-1 proto-oncogene ISO (MGI:MGI:3850801|PMID:19379700) RGD PMID:19379700 MGI:MGI:3850801 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301
JBrowse link
G Tcf7l1 transcription factor 7 like 1 ISO MGI:MGI:1202879 (MGI:MGI:4412144|PMID:19718027) RGD PMID:19718027 MGI:MGI:4412144 NCBI chr 4:100,492,796...100,660,401
Ensembl chr 4:100,491,798...100,660,140
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO MGI:MGI:1202876|MGI:MGI:1926344 (MGI:MGI:1276271|PMID:9697701), (MGI:MGI:1330442|PMID:10027409), (MGI:MGI:3841508|PMID:19251639), (MGI:MGI:4412144|PMID:19718027) RGD PMID:9697701, PMID:10027409, PMID:19251639, PMID:19718027 MGI:MGI:1276271, MGI:MGI:1330442, MGI:MGI:3841508, MGI:MGI:4412144 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tfap2c transcription factor AP-2 gamma ISO MGI:MGI:3040993 (MGI:MGI:4819480|PMID:20404091) RGD PMID:20404091 MGI:MGI:4819480 NCBI chr 3:170,550,314...170,558,197
Ensembl chr 3:170,550,314...170,558,194
JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 ISO (MGI:MGI:3849215|PMID:19497282) RGD PMID:19497282 MGI:MGI:3849215 NCBI chr13:90,379,203...90,405,627
Ensembl chr13:90,380,632...90,405,591
JBrowse link
G Vps72 vacuolar protein sorting 72 homolog ISO (MGI:MGI:3850801|PMID:19379700) RGD PMID:19379700 MGI:MGI:3850801 NCBI chr 2:196,277,961...196,289,549
Ensembl chr 2:196,277,978...196,289,561
JBrowse link
G Wnt7a Wnt family member 7A ISO MGI:MGI:1857704 (MGI:MGI:3849215|PMID:19497282) RGD PMID:19497282 MGI:MGI:3849215 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609
JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO (MGI:MGI:3818355|PMID:17980593) RGD PMID:17980593 MGI:MGI:3818355 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 ISO (MGI:MGI:5500826|PMID:23748442) RGD PMID:23748442 MGI:MGI:5500826 NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
JBrowse link
G Zhx2 zinc fingers and homeoboxes 2 ISO (MGI:MGI:3849211|PMID:19515908) RGD PMID:19515908 MGI:MGI:3849211 NCBI chr 7:97,559,653...97,707,872
Ensembl chr 7:97,559,841...97,695,739
JBrowse link
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sall1 spalt-like transcription factor 1 ISO MGI:MGI:3603818 (MGI:MGI:5563280|PMID:24550112) RGD PMID:24550112 MGI:MGI:5563280 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
mesenchymal stem cell maintenance involved in nephron morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Six2 SIX homeobox 2 ISO (MGI:MGI:3844906|PMID:18682239), (MGI:MGI:4950307|PMID:21350016), (MGI:MGI:5442222|PMID:22902740), (MGI:MGI:5563874|PMID:24598167) RGD PMID:18682239, PMID:21350016, PMID:22902740, PMID:24598167 MGI:MGI:3844906, MGI:MGI:4950307, MGI:MGI:5442222, MGI:MGI:5563874 NCBI chr 6:8,952,572...8,955,893
Ensembl chr 6:8,952,572...8,956,276
JBrowse link
G Wnt9b Wnt family member 9B ISO MGI:MGI:3526437 (MGI:MGI:4950307|PMID:21350016) RGD PMID:21350016 MGI:MGI:4950307 NCBI chr10:91,785,892...91,808,061
Ensembl chr10:91,785,893...91,807,937
JBrowse link
negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1b HNF1 homeobox B ISO MGI:MGI:1857856 (MGI:MGI:4430439|PMID:20040500) RGD PMID:20040500 MGI:MGI:4430439 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902
JBrowse link
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 ISO
ISS
(MGI:MGI:3704067|PMID:17314325)
GO_REF:0000024
RGD
UniProt
PMID:17314325 GO_REF:0000024, MGI:MGI:3704067 NCBI chr 1:264,493,579...264,585,073
Ensembl chr 1:264,504,591...264,583,329
JBrowse link
G Pax8 paired box 8 ISO
ISS
(MGI:MGI:3704067|PMID:17314325)
GO_REF:0000024
RGD
UniProt
PMID:17314325 GO_REF:0000024, MGI:MGI:3704067 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp7 bone morphogenetic protein 7 ISO MGI:MGI:1857654 (MGI:MGI:86404|PMID:9056639) RGD PMID:9056639 MGI:MGI:86404 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
positive regulation of somatic stem cell population maintenance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lbh LBH regulator of WNT signaling pathway ISO (MGI:MGI:5634223|PMID:25655704) RGD PMID:25655704 MGI:MGI:5634223 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Tp63 tumor protein p63 ISO (MGI:MGI:5634223|PMID:25655704) RGD PMID:25655704 MGI:MGI:5634223 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
regulation of somatic stem cell population maintenance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor ISS
ISO
GO_REF:0000024
(MGI:MGI:6323493|PMID:31005419)
UniProt
RGD
PMID:31005419 GO_REF:0000024, MGI:MGI:6323493 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Taf5l TATA-box binding protein associated factor 5 like ISO (MGI:MGI:6323493|PMID:31005419) RGD PMID:31005419 MGI:MGI:6323493 NCBI chr19:56,781,854...56,801,005
Ensembl chr19:56,781,859...56,799,445
JBrowse link
G Taf6l TATA-box binding protein associated factor 6 like ISO (MGI:MGI:6323493|PMID:31005419) RGD PMID:31005419 MGI:MGI:6323493 NCBI chr 1:224,974,238...224,986,819
Ensembl chr 1:224,974,208...224,986,291
JBrowse link

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.