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ONTOLOGY REPORT - ANNOTATIONS


Term:exon-exon junction complex
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Accession:GO:0035145 term browser browse the term
Definition:A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
Synonyms:exact_synonym: EJC;   exon junction complex


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exon-exon junction complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07055356.1 RGD:13792537
G AABR07055413.1 RGD:13792537
G AABR07062266.1 RGD:13792537
G Acin1 apoptotic chromatin condensation inducer 1 JBrowse link 15 33,288,369 33,333,256 RGD:1624291
G Alyref Aly/REF export factor JBrowse link 10 109,768,593 109,774,639 RGD:1624291
G Casc3 CASC3 exon junction complex subunit JBrowse link 10 86,724,534 86,744,485 RGD:1600115
RGD:13792537
RGD:1624291
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:1624291
G Magoh mago homolog, exon junction complex subunit JBrowse link 5 127,480,465 127,487,617 RGD:1624291
RGD:13792537
G Magohb mago homolog B, exon junction complex subunit JBrowse link 4 165,514,584 165,522,366 RGD:1624291
RGD:13792537
G Pnn pinin, desmosome associated protein JBrowse link 6 80,159,364 80,167,677 RGD:1624291
G Pym1 PYM homolog 1, exon junction complex associated factor JBrowse link 7 3,172,798 3,193,994 RGD:1624291
RGD:13792537
G R3hcc1l R3H domain and coiled-coil containing 1-like JBrowse link 1 261,753,295 261,833,437 RGD:1624291
RGD:1600115
G Rbm8a RNA binding motif protein 8A JBrowse link 2 198,755,261 198,758,028 RGD:1624291
RGD:13792537
G Sap18 Sin3A associated protein 18 JBrowse link 15 38,069,320 38,073,625 RGD:1624291
G Smg6 SMG6 nonsense mediated mRNA decay factor JBrowse link 10
10
61,526,024
61,771,912
61,542,583
62,007,030
RGD:1624291
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:1624291
G Tdrd3 tudor domain containing 3 JBrowse link 15 70,732,164 70,864,855 RGD:1600115
RGD:1624291
G Thrap3 thyroid hormone receptor associated protein 3 JBrowse link 5 144,178,248 144,221,318 RGD:1624291
RGD:1600115
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
G Upf2 UPF2, regulator of nonsense mediated mRNA decay JBrowse link 17 76,176,379 76,287,246 RGD:1624291
RGD:13792537
G Upf3a UPF3A, regulator of nonsense mediated mRNA decay JBrowse link 16 81,521,084 81,532,512 RGD:1624291
G Upf3b UPF3B, regulator of nonsense mediated mRNA decay JBrowse link X 123,713,327 123,731,431 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19809
    protein-containing complex 5770
      exon-exon junction complex 22
        exon-exon junction subcomplex mago-y14 0
Path 2
Term Annotations click to browse term
  cellular_component 19809
    cellular anatomical entity 19424
      organelle 12542
        membrane-bounded organelle 10872
          intracellular membrane-bounded organelle 9969
            nucleus 6778
              exon-exon junction complex 22
                exon-exon junction subcomplex mago-y14 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.